- Crohn's Disease Slideshow
- Crohn's Disease Quiz: Test Your Medical IQ
- Inflammatory Bowel Disease Slideshow
- What is budesonide (Entocort EC, Uceris)?
- What brand names are available for budesonide?
- Is budesonide (Entocort EC, Uceris) available as a generic drug?
- Do I need a prescription for budesonide (Entocort EC, Uceris)?
- Why is budesonide (Entocort EC, Uceris) prescribed to patients?
- What are the side effects of budesonide (Entocort EC, Uceris)?
- What is the dosage for budesonide (Entocort EC, Uceris)?
- Which drugs or supplements interact with budesonide (Entocort EC, Uceris)?
- Is budesonide (Entocort EC, Uceris) safe to use during pregnancy or while breastfeeding?
- What else should I know about budesonide (Entocort EC, Uceris)?
What is budesonide (Entocort EC, Uceris)?
Why is budesonide (Entocort EC, Uceris) prescribed to patients?
- Budesonide is used for the treatment of mild-to-moderately-active Crohn's disease involving the ileum (the second half of the small intestine) and/or ascending colon (the beginning of the large intestine). It is approved for maintaining remissions for up to three months.
- Budesonide also is used for the induction of remission in patients with active, mild to moderate ulcerative colitis.
- Budesonide rectal foam is used for the induction of remission in patients with active mild to moderate distal ulcerative colitis extending up to 40 cm from the anus.
What are the side effects of budesonide (Entocort EC, Uceris)?
The most common side effects of budesonide are:
- Upper respiratory tract infection
- Abdominal pain
- Back pain
- Flatulence (intestinal gas, farting)
- Abdominal distension
- Urinary tract infections (UTIs)
- Viral infections
- Low potassium
Excessive corticosteroid use causes:
Serious side effects of budesonide include:
What is the dosage for budesonide (Entocort EC, Uceris)?
- The recommended dose for active Crohn's disease is 9 mg once daily in the morning for up to 8 weeks.
- The 8 week course may be repeated for recurring episodes.
- The dose for maintenance of remission is 6 mg once daily for 3 months.
- The recommended dosage for the induction of remission in adult patients with active, mild to moderate ulcerative colitis is one 9 mg extended release tablet to be taken once daily in the morning for up to 8 weeks.
- The recommended dose for the spray is 1 spray administered twice daily for 2 weeks followed by 1 spray once daily for 4 weeks.
Which drugs or supplements interact with budesonide (Entocort EC, Uceris)?
Medicines which block the liver enzymes that break down budesonide may lead to higher blood concentrations and more side effects of budesonide. Such medications include
- ketoconazole (Nizoral),
- fluconazole (Diflucan),
- itraconazole (Sporanox),
- clarithromycin (Biaxin),
- verapamil (for example, Calan; Isoptin; Covera HS),
- diltiazem (for example, Cardizem; Dilacor),
- ritonavir (Norvir; Kaletra),
- indinavir (Crixivan), and
- saquinavir (Invirase, Fortovase).
Grapefruit juice has a similar effect and should not be consumed by patients taking budesonide.
Is budesonide (Entocort EC, Uceris) safe to use during pregnancy or while breastfeeding?
- There are no adequate studies in pregnant women. Budesonide should only be used in pregnant women if the benefits outweigh the unknown risk. Use of budesonide during pregnancy may suppress the adrenal glands of the infant.
- Budesonide is secreted in human breast milk. Because of the potential for adverse reactions in nursing infants from any corticosteroid, a decision should be made whether to discontinue nursing or discontinue the budesonide.
What else should I know about budesonide (Entocort EC, Uceris)?
What preparations of budesonide (Entocort EC, Uceris) are available?
- Capsules: 3 mg
- Tablets (Extended Release): 9 mg
- Rectal foam: 2 mg per spray
How should I keep budesonide (Entocort EC, Uceris) stored?
- Capsules should be stored between 15 C and 30 C (59 F and 86 F)
How does budesonide (Entocort EC, Uceris) work?
- The naturally-occurring hormone whose actions budesonide mimics, is cortisol or hydrocortisone which is produced by the adrenal glands. Glucocorticoid steroids have potent anti-inflammatory actions. Crohn's disease is a chronic inflammatory bowel disease of unknown cause that results in diarrhea, crampy abdominal pain, fever and bleeding from the rectum. The active ingredient in Budesonide, is released from granules in the ileum of the small intestine and the right (proximal) colon, where the inflammation of Crohn's disease occurs. Budesonide acts directly by contact with the ileum and colon. Budesonide that is absorbed into the body travels first to the liver where it is broken-down and eliminated from the body. This prevents the majority of the absorbed drug from being distributed to the rest of the body. As a result, budesonide causes fewer severe side effects throughout the body than other corticosteroids.
When was budesonide (Entocort EC, Uceris) approved by the FDA?
- The FDA approved budesonide in October of 2001.
Budesonide (Entocort EC, Uceris) is a medication prescribed for the treatment of mild-to-moderately active Crohn's disease. Side effects include:
Multimedia: Slideshows, Images & Quizzes
Ulcerative Colitis Quiz: Diet, Symptoms & Treatment
What is ulcerative colitis and what risks are associated with suffering over the long term? Take this Ulcerative Colitis Quiz to...
Crohn's Disease Quiz
What causes Crohn's disease? What are the symptoms of Crohn's disease? How is Crohn's treated? Take this quiz to get the facts...
Inflammatory Bowel Disease (IBD) Causes, Symptoms, Treatment
What is inflammatory bowel disease? IBD can include Crohn's disease and ulcerative colitis. Learn more about testing, treatments,...
Ulcerative Colitis Symptoms, Causes, and Treatment
Ulcerative Colitis is a form of inflammatory bowel disease and is slightly different than Crohn's disease. Your diet can impact...
Crohn's Disease Causes, Symptoms, Diet
What is Crohn's disease? Get more information on this digestive disorder and how Crohn's can affect your diet. Learn more about...
Related Disease Conditions
Asthma is a condition in which hyperreactive airways constrict and result in symptoms like wheezing, coughing, and shortness of...
Crohn's Disease (Symptoms, Causes, Diet, Treatment, Life Expectancy)
Crohn's disease is a chronic inflammatory disease, primarily involving the small and large intestine, but which can affect...
Hay Fever (Allergic Rhinitis)
Hay fever (allergic rhinitis) is an irritation of the nose caused by pollen and is associated with the following allergic...
Ulcerative colitis is a chronic inflammation of the colon. Symptoms include abdominal pain, diarrhea, and rectal bleeding....
Microscopic Colitis (Lymphocytic Colitis and Collagenous Colitis)
Microscopic colitis (lymphocytic colitis and collagenous colitis) is a disease of inflammation of the colon. Microscopic colitis...
COPD (Chronic Obstructive Pulmonary Disease) Symptoms, Causes, Stages, Life Expectancy
COPD or chronic obstructive pulmonary disease is a lung condition caused by smoking tobacco, exposure to secondhand smoke, and/or...
Chronic Rhinitis and Post-Nasal Drip (Symptoms, Treatment)
Chronic rhinitis and post-nasal drip symptoms include an itchy, runny nose, sneezing, itchy ears, eyes, and throat. Seasonal...
Inflammatory Bowel Disease (Intestinal Problems of IBD)
The inflammatory bowel diseases (IBD) are Crohn's disease (CD) and ulcerative colitis (UC). The intestinal complications of...
Primary Biliary Cirrhosis Treatment (PBC)
Primary biliary sclerosis (PBC) is thought to be an autoimmune disorder that involves the deterioration of the liver's small bile...
Colitis (Symptoms, Types, and Treatments)
Colitis refers to inflammation of the inner lining of the colon. Symptoms of the inflammation of the colon lining include...
Ulcerative Colitis Diet
An ulcerative colitis diet plan can help a person with the disease avoid foods and drinks that trigger flares. There also are...
Is Colitis Contagious?
Colitis is a term that us used to describe inflammation of the colon. The terms enteritis, proctitis, and inflammatory bowel...
Crohn's Disease vs. Ulcerative Colitis (UC)
Crohn's disease and ulcerative colitis are diseases that cause inflammation of part of or the entire digestive tract (GI)....
Treatment & Diagnosis
- Ulcerative Colitis FAQs
- Crohn's Disease FAQs
- Medication Disposal
- How To Reduce Your Medication Costs
- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Drugs: Buying Prescription Drugs Online Safely
- Drugs: The Most Common Medication Errors
- Dangers of Mixing Medications
- Generic Drugs, Are They as Good as Brand-Names?
Medications & Supplements
Prevention & Wellness
Crohn's Disease Resources
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.