Brussels Sprout

Reviewed on 6/11/2021
Other Name(s):

Bao Zi Gan Lan, Brassica oleracea, Brassica oleracea var. gemmifera, Brüsseler Kohl, Brysselkål, Cavola a Germoglio, Cavola di Bruxelles, Chou À Mille Pommes, Chou de Bruxelles, Col de Bruselas, Coles de Bruselas, Couve de Bruxelas, Kapusta Warzywna Brukselka, Kohlsprossen, Me Kanran, Me Kyabetsu, Repollo de Bruselas, Rooskapsas, Rosen-Wirsing, Rosenkål, Rosenkohl, Ruusukaali, Spruit, Ya Gan Lan.


Brussels sprout is a leafy green vegetable that is commonly eaten as a food source or as a medicine.

Brussels sprout is taken by mouth as an antioxidant; for constipation, scurvy, and wound healing; and to prevent prostate problems, bladder cancer, breast cancer, heart disease, diabetes, stroke, lung cancer, birth defects due to low folic acid levels, non-Hodgkin lymphoma, osteoporosis, pancreatic cancer, and prostate cancer.

How does it work?

Brussels sprout contains chemicals that are thought to help prevent cancer. For breast cancer in particular, eating Brussels sprout might change the way estrogen is used in the body, which might reduce the risk of breast cancer. Brussels sprout also has antioxidant activity.


Next to red peppers, you can get the most vitamin C from ________________. See Answer

Uses & Effectiveness

Insufficient Evidence to Rate Effectiveness for...

  • Benign prostatic hyperplasia (BPH): Some early research suggests that eating large amounts of Brussels sprout is not linked with a sizable reduction in the risk of BPH.
  • Bladder cancer: There is some evidence that people who eat large amounts of Brussels sprout and related vegetables have a lower risk of developing bladder cancer.
  • Breast cancer: Some early research suggests that eating Brussels sprout and related vegetables is linked with a slight increase in the risk of breast cancer in premenopausal women. However, other early research suggests that eating Brussels sprout and related vegetables is not associated with a higher or lower risk of breast cancer in postmenopausal women or women in general.
  • Diabetes: Early research suggests that women who eat Brussels sprout and related vegetables do not have a lower risk of developing type 2 diabetes.
  • Stroke that is caused by a clot (ischemic stroke): Early research suggests that eating larger amounts of Brussels sprout and related vegetables is linked with a lower risk of ischemic stroke.
  • Lung cancer: Some research shows that eating larger amounts of Brussels sprout and broccoli is linked with a lower risk of developing lung cancer.
  • Non-Hodgkin lymphoma: Early research suggests that women who eat larger amounts of Brussels sprout and related vegetables have a lower risk of developing non-Hodgkin lymphoma. However, eating Brussels sprout and related vegetables does not seem to be linked with a lower risk of non-Hodgkin lymphoma in men.
  • Pancreatic cancer: Early research suggests that people who eat larger amounts of Brussels sprout do not have a lower risk of developing pancreatic cancer.
  • Prostate cancer: Some early research shows that people who eat larger amounts of Brussels sprout and related vegetables have a lower risk of developing prostate cancer.
  • Constipation.
  • Scurvy.
  • Wound healing.
  • Heart disease.
  • Birth defects due to low folic acid levels (neural tube defects).
  • Osteoporosis.
  • Other conditions.
More evidence is needed to rate the effectiveness of Brussels sprout for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

Side Effects

Brussels sprout is LIKELY SAFE when consumed in food amounts. However, eating Brussels sprout might cause gas.

It isn't known if Brussels sprout is safe or what the possible side effects might be when taken in medicinal amounts.


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Special Precautions & Warnings

Pregnancy and breast-feeding: There isn't enough information about the safety of eating Brussels sprout in medicinal amounts during pregnancy or breast-feeding. Stay on the safe side and stick to usual food amounts.

Irritable bowel syndrome (IBS): Eating Brussels sprout might cause gas. This could make symptoms of IBS worse.


Acetaminophen (Tylenol, others)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.

The body breaks down acetaminophen (Tylenol, others) to a get rid of it. Brussels sprout might increase the breakdown of acetaminophen (Tylenol, others). Taking Brussels sprout along with acetaminophen (Tylenol, others) might decrease the effectiveness of acetaminophen (Tylenol, others).

Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.

Some medications are changed and broken down by the liver.

Brussels sprout might increase how quickly the liver breaks down some medications. Taking Brussels sprout along with some medications that are changed by the liver can decrease the effectiveness of some medications. Before taking Brussels sprout talk to your healthcare provider if you take any medications that are changed by the liver.

Some of these medications that are changed by the liver include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), theophylline, zileuton (Zyflo), zolmitriptan (Zomig), and others.

Medications changed by the liver (Glucuronidated Drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.

The liver helps the body break down and change some medications. The body breaks down some medications to get rid of them. Brussels sprout might increase how quickly the body breaks down some medications changed by the liver. Taking Brussels sprout along with these medications changed by the liver might decrease the effectiveness of some medications changed by the liver.

Some of these medications changed by the liver include acetaminophen, atorvastatin (Lipitor), diazepam (Valium), digoxin, entacapone (Comtan), estrogen, irinotecan (Camptosar), lamotrigine (Lamictal), lorazepam (Ativan), lovastatin (Mevacor), meprobamate, morphine, oxazepam (Serax), and others.

Oxazepam (Serax)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.

The body breaks down oxazepam (Serax) to get rid of it. Brussels sprout can increase how quickly the body gets rid of oxazepam (Serax). Taking Brussels sprout along with oxazepam (Serax) might decrease the effectiveness of oxazepam (Serax).

Warfarin (Coumadin)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.

Brussels sprout contains large amounts of vitamin K. Vitamin K is used by the body to help blood clot. Warfarin (Coumadin) is used to slow blood clotting. By helping the blood clot, Brussels sprout might decrease the effectiveness of warfarin (Coumadin). Be sure to have your blood checked regularly. The dose of your warfarin (Coumadin) might need to be changed.


The appropriate dose of Brussels sprout depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for Brussels sprout. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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