- Understanding COPD Slideshow
- COPD (Chronic Obstructive Pulmonary Disease) Quiz
- Energy Foods for COPD Slideshow Pictures
What is Bronchitol, and how does it work?
- Bronchitol is a prescription medicine that is used along with other therapies to improve lung function in people 18 years of age and older with cystic fibrosis (CF).
- Bronchitol is only for adults who have passed the Bronchitol Tolerance Test (BTT). Your first dose of Bronchitol is given during the BTT by your healthcare provider and tests if Bronchitol is right for you. Your healthcare provider will use equipment to monitor you and have medicine ready if you have bronchospasms during the test. If you have bronchospasms during your BTT, then you should not be prescribed Bronchitol.
Bronchitol should not be used in children and adolescents. It is not known if Bronchitol is safe and effective in children under 18 years of age.
What are the side effects of Bronchitol?
Bronchitol may cause serious side effects, including:
- sudden breathing problems immediately after inhaling your medicine. Use your short-acting bronchodilator or rescue medicine if you have sudden breathing problems. Get emergency medical care right away if your bronchodilator or rescue medicine does not relieve the symptoms.
- coughing up of blood (hemoptysis). This is a serious but common side effect. Coughing up blood in your mucus can happen while you are using Bronchitol. Call your healthcare provider or get emergency medical care right away if you cough up a large amount of blood.
The most common side effects of Bronchitol include:
- coughing up of blood
- pain or irritation in the back of your mouth and throat and discomfort when swallowing
- joint pain
- bacteria in your sputum
Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of Bronchitol. You can ask your healthcare provider or pharmacist for more information.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to Chiesi USA, Inc. at 1-888-661-9260.
What is the dosage for Bronchitol?
Required Testing And Evaluation Prior To Prescribing Bronchitol (Bronchitol Tolerance Test)
Prior to prescribing Bronchitol for treatment of cystic fibrosis, the Bronchitol Tolerance Test (BTT) must be administered and performed under the supervision of a healthcare practitioner who is able to manage acute bronchospasm, to identify patients who are suitable candidates for Bronchitol maintenance therapy.
- Perform BTT to identify patients who experience bronchospasm, a decrease in FEV1, or a decrease in oxygen saturation with administration of Bronchitol. If a patient experiences any of these events during the BTT, the patient has failed the BTT. Do not prescribe Bronchitol. If a patient does not experience any of these events during BTT, the patient has passed the BTT and is a candidate for Bronchitol therapy.
- Ensure that rescue medication and resuscitation equipment are available for immediate use during the BTT.
- Do not perform the BTT if the patient is considered clinically unstable.
See the prescribing information for complete instructions and to avoid medication errors associated with BTT dosing and procedures.
Do not use Bronchitol add-on maintenance therapy in patients who fail the BTT.
Recommended Dosage For Treatment Of Cystic Fibrosis
- For patients who have passed the BTT, the recommended dosage of Bronchitol is 400 mg twice a day by oral inhalation (the contents of 10 capsules administered individually) via the inhaler [see Required Testing And Evaluation Prior To Prescribing Bronchitol (Bronchitol Tolerance Test)].
- A short-acting bronchodilator should be administered by oral inhalation, 5-15 minutes before every dose of Bronchitol.
- Bronchitol should be taken once in the morning and once in the evening, with the later dose taken at least 2-3 hours before bedtime.
Use And Maintenance Of Inhaler
- Instruct patients on safe hygiene practices (clean and dry hands thoroughly) and correct inhaler use, including loading of capsules and proper inhalation technique per the Patient Instructions for Use.
- The Bronchitol inhaler should be discarded and replaced after 7 days of use.
- If the inhaler does need to be washed, the patient should allow the inhaler to thoroughly air dry before next use.
What drugs interact with Bronchitol?
- No formal drug interaction studies have been conducted with mannitol, the active ingredient in Bronchitol.
Is Bronchitol safe to use while pregnant or breastfeeding?
- There are no adequate and well-controlled studies of Bronchitol in pregnant women.
- The available data on Bronchitol use in pregnant women are not sufficient to inform any drug-associated risks for major birth defects and miscarriage.
- There are risks to the mother associated with cystic fibrosis in pregnancy.
- Bronchitol should be used during pregnancy only if the potential benefit justifies the potential risk to the mother and fetus.
- It is not known whether Bronchitol is excreted in human breast milk.
- The developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for Bronchitol and any potential adverse effects on the breastfed child from Bronchitol or from the underlying maternal condition.
Latest Lungs News
Daily Health News
Bronchitol is a prescription medicine that is used along with other therapies to improve lung function in people 18 years of age and older with cystic fibrosis (CF) who have passed the Bronchitol Tolerance Test (BTT). Serious side effects of Bronchitol include sudden breathing problems and coughing up of blood (hemoptysis).
Multimedia: Slideshows, Images & Quizzes
COPD (Chronic Obstructive Pulmonary Disease) Quiz
COPD is a combination of three conditions? Take this quiz to learn the three conditions that make up the pulmonary disease called...
Lung Cancer Quiz: Signs and Symptoms
Lung cancer is the number one cause of cancer deaths in both men and women in the U.S. and worldwide. Get the facts about lung...
Picture of Lung Cancer
Cancer of the lung, like all cancers, results from an abnormality in the body's basic unit of life, the cell. See a picture of...
COPD Foods to Boost Your Health - COPD Diet Tips
Boost your energy and combat COPD with these diet tips. Which foods can help patients with COPD? Which foods to avoid for COPD?...
Lung Cancer: Early Signs, Symptoms, Stages
Learn about lung cancer early warning signs, symptoms and treatments. What causes stage IV lung cancer? Get more information on...
COPD Lung Symptoms, Diagnosis, Treatment
COPD is a pulmonary disorder caused by obstructions in the airways of the lungs leading to breathing problems. Learn about COPD...
Lung Cancer Risks: Myths and Facts
Learn about lung cancer myths and facts. Explore how cigar smoke, menthol, and pollution can increase your risk of lung cancer...
10 Smart Exercises for People With COPD: Pictures
The more you exercise, the better you'll feel with COPD. Breathe easier with these 10 exercises from WebMD.
Respiratory Illnesses: 13 Types of Lung Infections
Is your cough caused by a cold, flu, pneumonia or something else? Learn causes of respiratory infection like bronchitis,...
Lung and Respiratory Health: Reasons You're Short of Breath
Have you ever found yourself gasping for air after just a short flight of stairs? You may just need to do a bit more exercise, or...
Lung and Respiratory Health: Surprising Causes of Lung Damage
Carpets, fireworks, and hot tubs are some of the unexpected things that can hurt your lungs. Find out what you can do to prevent...
Related Disease Conditions
Cystic fibrosis is a disease of the mucus and sweat glands. Cystic fibrosis is an inherited disease. The outcome of the disease leaves the body malnourished, with bulky and fouls smelling stools, vitamin insufficiency, gas, painful or swollen abdomen, infertility, susceptible to heat emergencies, and respiratory failure. There is no cure for cystic fibrosis, treatment of symptoms is used to manage the disease.
COPD (Chronic Obstructive Pulmonary Disease)
COPD or chronic obstructive pulmonary disease is a lung condition caused by smoking tobacco, exposure to secondhand smoke, and/or air pollutants. Conditions that accompany COPD include chronic bronchitis, chronic cough, and emphysema. Symptoms of COPD include shortness of breath, wheezing, and chronic cough. Treatment of COPD includes GOLD guidelines, smoking cessation, medications, and surgery. The life expectancy of a person with COPD depends on the stage of the disease.
Emphysema is a COPD (chronic obstructive pulmonary disease) that often occurs with other obstructive pulmonary problems and chronic bronchitis. Causes of emphysema include chronic cigarette smoking, exposure to secondhand smoke, air pollution, and in the underdeveloped parts of the world. Symptoms of emphysema include chronic cough, chest discomfort, breathlessness, and wheezing. Treatments include medication and lifestyle changes.
Interstitial Lung Disease (Interstitial Pneumonia)
Interstitial lung disease refers to a variety of diseased that thicken the tissue between the lungs' air sacks. Viruses, bacteria, tobacco smoke, environmental factors, cancer, and heart or kidney failure can all cause interstitial lung disease. Shortness of breath, cough, and vascular problems are symptoms caused by interstitial lung disease, and their treatment depends on the underlying cause of the tissue thickening.
COPD vs. Asthma (Differences and Similarities)
COPD (chronic obstructive pulmonary disease) and asthma both have common symptoms like coughing, wheezing, shortness of breath, and a tight feeling in the chest. COPD is caused by tobacco smoking, while asthma is caused by your inherited genetic makeup and their interactions with the environment. Risk factors for asthma are obesity, exposure to cigarette smoke (even secondhand smoke), and personal history of hay fever. There is no cure for either disease, but symptoms can be managed with medication. A person with asthma has a better prognosis and life expectancy than someone with COPD.
COPD vs. Emphysema
COPD (chronic obstructive pulmonary disease) is the term doctors and other healthcare professionals use to describe a group of serious, progressive (worsens over time), chronic lung diseases that include emphysema, chronic bronchitis, and sometimes asthma. The number one cause of COPD or emphysema, is smoking, and smoking is the third leading cause of death in the US.
What are the Four Stages of COPD?
COPD (chronic obstructive pulmonary disease) is a group of diseases that cause an inflammatory reaction and irreversible damage in the lungs. The result is obstruction of normal airflow and breathing difficulties. COPD is a lifelong condition with periods of flare ups, and is not curable in any stage of the disease. Emphysema and chronic bronchitis are the most common diseases that make up COPD.
Can People With COPD Get Better?
Chronic obstructive pulmonary disease (COPD) is not curable in any stage of the disease. With early diagnosis and treatment, disease progression and flare-ups can be controlled.
End-Stage COPD: Signs, Symptoms, and Prognosis
Chronic obstructive pulmonary disease (COPD) is a group of diseases causing an inflammatory reaction and irreversible damage to the lungs. They cause obstruction of airflow and difficulty breathing.
How Long Can You Live With Cystic Fibrosis?
The life expectancy of patients with cystic fibrosis has improved over the last 50 years. The improved chances of survival are due to advances in early diagnosis, supportive care, nutritional care, and infection control.
Can You Get Cystic Fibrosis at Any Age?
Cystic fibrosis is classically a disease of childhood that progresses into adulthood. If you have a genetic defect related to cystic fibrosis (CF), you are more likely to be born with cystic fibrosis. The symptoms might appear later, and hence, the age at diagnosis varies widely.
How Is a Person's Life Affected By Cystic Fibrosis?
How long can you live with cystic fibrosis? Learn the signs of cystic fibrosis and what to do if someone you know has cystic fibrosis.
Cystic Fibrosis Life Span
Cystic fibrosis (CF) is a progressive disease that needs daily care. Though a patient needs to take medications lifelong, most people with cystic fibrosis are usually able to attend school and work. The improvement in screening and treatments mean that people with CF now may live into their mid- to late 30s or 40s, and some are living into their 50s.
Treatment & Diagnosis
- COPD (Chronic Obstructive Pulmonary Disease) FAQs
- Lung Cancer FAQs
- Pulmonary Embolism -Lung Blood Clot Risk Factors In Women
- What Is the Treatment For Polymyositis in the Lungs (Pulmonary)?
- Is it Common to Have Pneumothorax with COPD?
- What Lung Diseases Cause the Most Hospitalizations?
- What Are Calcified Lung Nodules?
- What Is Stage IV COPD?
Medications & Supplements
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.