- What is oral bromocriptine?
- What are the uses for oral bromocriptine?
- What are the side effects of oral bromocriptine?
- What is the dosage for oral bromocriptine?
- Which drugs or supplements interact with oral bromocriptine?
- Is oral bromocriptine safe to take if I'm pregnant or breastfeeding?
- What else should I know about oral bromocriptine?
What is oral bromocriptine?
Bromocriptine belongs to a class of medication called anticholinergics that work by blocking a certain natural substance (acetylcholine). This helps decrease muscle stiffness, sweating, and the production of saliva, and helps improve walking ability in people with Parkinson's disease. Anticholinergics such as bromocriptine can stop severe muscle spasms of the back, neck, and eyes that are sometimes caused by psychiatric drugs. It can also decrease other side effects such as muscle stiffness/rigidity (extrapyramidal signs-EPS).
What brand names are available for oral bromocriptine?
Is oral bromocriptine available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for oral bromocriptine?
What are the uses for oral bromocriptine?
Bromocriptine is used to treat hyperprolactinemia, acromegaly, and signs and symptoms of Parkinson's disease. Bromocriptine is used to treat symptoms of Parkinson's disease or involuntary movements due to the side effects of certain psychiatric drugs (antipsychotics such as chlorpromazine/haloperidol).
What are the side effects of oral bromocriptine?
- Low blood pressure (hypotension) has been reported in some patients taking bromocriptine. The risk of experiencing hypotension is particularly of concern when treatment is first started or after increases in dose. Patients who are just starting treatment are advised to stand up slowly when getting up from a sitting or lying down position to avoid injury from falls due to dizziness or lightheadedness (orthostatic hypotension).
- Some patients with pre-existing mental disorders may experience worsening psychotic symptoms or bromocriptine may reduce the effectiveness of some medications used to treat psychotic disorders.
- Bromocriptine may cause sleepiness or drowsiness. Patients should not drive or operate machinery until they know how they will respond to the medication.
- Certain medications used to treat schizophrenia and other mental disorders may interact with the way bromocriptine works.
What is the dosage for oral bromocriptine?
Bromocriptine should be taken with meals.
- The dose for treating hyperprolactinemia is 2.5 to 15 mg daily. The initial dose for treating acromegaly is 1.25 to 2.5 mg at night. The dose may be increased by 1.25 to 2.5 mg every 3 to 7 days up to a maximum dose of 100 mg daily.
- Parkinson's treatment is started at 1.25 mg every 12 hours. The dose may be increased by 2.5 mg a day every 2 to 4 weeks up to a maximum dose of 100 mg daily.
Which drugs or supplements interact with oral bromocriptine?
- Certain medications used to treat schizophrenia and other mental disorders may interact with the way bromocriptine works. Patients receiving treatment for mental disorders should check with their doctor or pharmacist before beginning a regimen that contains bromocriptine.
- Bromocriptine may decrease the effectiveness of ergot related drugs that are used to treat migraine headaches. This combination should be avoided.
- Bromocriptine is extensively metabolized or broken down by a group of liver enzymes known as the CYP3A4 enzymes. Drugs that increase or decrease the activity of these enzymes should not be combined with bromocriptine.
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Is oral bromocriptine safe to take if I'm pregnant or breastfeeding?
There are no adequate and well-controlled studies of bromocriptine use in pregnant women. Bromocriptine should be used during pregnancy only if the potential benefit justifies the potential risk to the unborn baby.
What else should I know about oral bromocriptine?
What preparations of oral bromocriptine are available?
Tablets: 2.5 mg; Capsules: 5 mg
How should I keep oral bromocriptine stored?
Bromocriptine tablets and capsules should be stored at room temperature, between 15 C and 30 C (59 F and 86 F).
Bromocriptine (Parlodel) is prescription drug used to treat hyperprolactinemia, acromegaly, and signs and symptoms of Parkinson's disease. Review side effects, drug interactions, dosing, storage, and pregnancy and breastfeeding safety information prior to taking this medication.
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Parkinson's disease is a slowly progressive neurological disease characterized by a fixed inexpressive face, a tremor at rest, slowing of voluntary movements, a gait with short accelerating steps, peculiar posture and muscle weakness, caused by degeneration of an area of the brain called the basal ganglia, and by low production of the neurotransmitter dopamine. Most patients are over 50, but at least 10 percent are under 40.
Migraine headache is a type of headache associated with a sensitivity to light, smells, or sounds, eye pain, severe pounding on one side of the head, and sometimes nausea and vomiting. The exact cause of migraine headaches is not known. Triggers for migraine headaches include certain foods, stress, hormonal changes, strong stimuli (loud noises), and oversleeping. Treatment guidelines for migraines include medicine, pain management, diet changes, avoiding foods that trigger migraines, staying hydrated, getting adequate sleep, and exercising regularly. Prevention of migraine triggers include getting regular exercise, drinking water daily, reducing stress, and avoiding trigger foods.
Amenorrhea (including hypothalmic amenorrhea) is a condition in which there is an absence of menstrual periods in a woman. There are two types of amenorrhea: primary and secondary. Treatment of amenorrhea depends on the type. In primary, surgery may be an option and in secondary amenorrhea medication or lifestyle changes may be treatment options. We go over the definition of amenorrhea, causes, and treatment options for amenorrhea.
Prolactinoma (Pituitary Tumor)
Prolactinoma is an adenoma (benign tumor) of the pituitary gland. Causes of many prolactinomas are unknown. Symptoms in women include: changes in menstruation and infertility, decreased libido, or painful intercourse due to vaginal dryness. The most common symptom in men is impotence (erectile dysfunction). Treatments for prolactinomas include medication and surgery.
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