What is brimonidine, and how does it work (mechanism of action)?
Brimonidine is is an ophthalmic solution used for the treatment of one type of glaucoma, open-angle glaucoma. In this type of glaucoma, too much fluid (aqueous humor) is made within the eye and causes high pressures within the eye. The pressure damages the nerves in the eye responsible for vision, and this ultimately causes blindness. Brimonidine reduces the body's production of aqueous humor and increases the flow of aqueous humor out of the eye, resulting in a decrease in pressure. It accomplishes this by stimulating alpha type 2 receptors selectively in the eye with less effect on alpha type 2 receptors elsewhere in the body. It is the first drug of its class to be used for glaucoma. Brimonidine was approved by the FDA in 1996.
What brand names are available for brimonidine?
Is brimonidine available as a generic drug?
Do I need a prescription for brimonidine?
What are the side effects of brimonidine?
Common side effects include:
- dry eyes,
- red eyes,
- irritation of the eyes,
- blurred vision,
- a sensation of a foreign body in the eye, and
Other important side effects of brimonidine include:
What is the dosage for brimonidine?
The usual dose is one drop into each affected eye three times daily with each application approximately 8 hours apart.
Is brimonidine safe to take if I'm pregnant or breastfeeding?
It is not known if brimonidine is secreted in breast milk.
What else should I know about brimonidine?
What preparations of brimonidine are available?
Ophthalmic solution: 0.1%, 0.15%, and 0.2%.
How should I keep brimonidine stored?
Brimonidine should be kept at room temperature, 15 C to 30 C (59 F to 86 F) and protected for direct light.
Brimonidine (Alphagan) is a drug prescribed for the treatment of open-angle glaucoma. Side effects, drug interactions, and pregnancy safety information should be reviewed prior to taking this medication.
Related Disease Conditions
Treatment & Diagnosis
- Drugs: The Most Common Medication Errors
- Medication Disposal
- Dangers of Mixing Medications
- How To Reduce Your Medication Costs
- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Drugs: Buying Prescription Drugs Online Safely
- Generic Drugs, Are They as Good as Brand-Names?
Medications & Supplements
Prevention & Wellness
Latest Health News
- Healthy Living Boosts Life Span, Even for Former Smokers
- AHA News: For This Race Car Driver, Curing a Racing Heart Was Key to Crossing the Finish Line
- Money, Good Info Can't Undo Resistance to COVID Vaccine: Study
- U.S. Suicide Rates Rose in 2021, Reversing 2 Years of Decline
- After Ian's Destruction: How to Safely Enter, Clean Flood-Damaged Homes
- More Health News »
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
FDA Prescribing Information