Bridelia

What other names is Bridelia known by?

Asas, Assas, Bridelia cathartica, Bridelia ferruginea, Bridelia grandis, Bridelia micrantha, Bridelia monoica, Bridelia retusa, Bridelia stipularis, Mist Bredina.

What is Bridelia?

Bridelia is the name for a plant genus. The leaf, stem bark, and root are used to make medicine.

People take Bridelia leaf, stem bark, or root by mouth to prevent pregnancy, to cause labor, for malaria, AIDS/HIV, anemia, asthma, cancer, colic, cough, diabetes, diarrhea, enlarged spleen, gonorrhea, hernia, joint pain, menstruation that is abnormal or painful, stomachaches and other stomach problems, syphilis, thrush, to kill parasites, urinary tract infections, yellow fever, yellow skin discoloration (jaundice), as an insecticide, and as a strong laxative.

People apply Bridelia to the skin for wounds, to the scalp for headaches, and to the eyes for sore eyes.

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Insufficient Evidence to Rate Effectiveness for...

More evidence is needed to rate the effectiveness of Bridelia for these uses.

How does Bridelia work?

Bridelia might reduce swelling, lessen pain, and lower fevers. Bridelia might also prevent the growth of organisms that cause infections. Bridelia might have similar effects as the female hormone estrogen. It might also have antioxidant effects.

Are there safety concerns?

It isn't known if Bridelia is safe. There is concern that Bridelia might lower blood pressure and heart rate.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Bridelia is LIKELY UNSAFE when used during pregnancy. There is concern that Bridelia might stimulate the uterus and cause labor. Avoid using.

Not enough is known about the use of Bridelia during breast-feeding. Stay on the safe side and avoid use.

Bleeding disorders: Bridelia might slow blood clotting. This might increase the risk of bleeding or bruising in people with bleeding disorders.

Hormone-sensitive conditions such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Bridelia might have the same effects as the female hormone estrogen. If you have any condition that might be made worse by exposure to estrogen, don't use Bridelia.

Low blood pressure: Bridelia might decrease blood pressure. Don't take Bridelia if you already have low blood pressure.

Surgery: Bridelia might slow blood clotting. In theory, Bridelia might cause extra bleeding or affect blood pressure control during and after surgery. Stop using it at least 2 weeks before a scheduled surgery.

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Are there any interactions with medications?


EstrogensInteraction Rating: Moderate Be cautious with this combination.Talk with your health provider.

Bridelia might have some of the same effects as estrogen. However, Bridelia is not as strong as estrogen pills. Taking Bridelia along with estrogen pills might decrease the effects of estrogen pills.

Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others.


Medications for high blood pressure (Antihypertensive drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.

Bridelia might lower blood pressure. Taking Bridelia along with medications for high blood pressure might cause your blood pressure to go too low.

Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.


Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.

Bridelia might slow blood clotting. Taking Bridelia along with medications that also slow clotting might increase the chances of bruising and bleeding.

Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.

Dosing considerations for Bridelia.

The appropriate dose of Bridelia depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for Bridelia. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

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Reviewed on 9/17/2019
References

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Akinpelu DA, Olorunmola FO. Antimicrobial activity of Bridelia ferruginea fruit. Fitoterapia 2000;71(1):75-6. View abstract.

Cimanga K, De Bruyne T, Apers S, et al. Complement-Inhibiting constituents of Bridelia ferruginea stem bark. Planta Med 1999;65(3):213-7. View abstract.

Cimanga K, Ying L, De Bruyne T, et al. Radical scavenging and xanthine oxidase inhibitory activity of phenolic compounds from Bridelia ferruginea stem bark. J Pharm Pharmacol 2001;53(5):757-61. View abstract.

Corallo A, Foungbe S, Davy M, Cohen Y. Cardiovascular pharmacology of aqueous extract of the leaves of Bridelia atroviridis Muell. Arg. (Euphorbiaceae) in the rat. J Ethnopharmacol 1997;57(3):189-96. View abstract.

Corallo A, Savineau JP, Tricoche R, Foungbe S. The uterotonic action of the aqueous extract of Bridelia atroviridis in the rat. Fundam Clin Pharmacol 1991;5(4):319-29. View abstract.

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Jayasinghe L, Kumarihamy BM, Jayarathna KH, et al. Antifungal constituents of the stem bark of Bridelia retusa. Phytochemistry 2003;62(4):637-41. View abstract.

Jurg A, Tomas T, Pividal J. Antimalarial activity of some plant remedies in use in Marracuene, southern Mozambique. J Ethnopharmacol 1991;33(1-2):79-83. View abstract.

Lin J, Puckree T, Mvelase TP. Anti-diarrhoeal evaluation of some medicinal plants used by Zulu traditional healers. J Ethnopharmacol 2002;79(1):53-6. View abstract.

Malkani NP. "Plants of Dehli: scientific names and their meaning." Plant Taxonomy: past, present, and future. Ed. Gupta R. New Delhi: The Energy and Resource Institute (TERI), 2011.

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Njamen D, Magne Nde CB, Tanee Fomum Z, Vollmer G. Effects of the extracts of some tropical medicinal plants on estrogen inducible yeast and Ishikawa screens, and on ovariectomized Wistar rats. Pharmazie 2008;63(2):164-8. View abstract.

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Ramesh N, Viswanathan MB, Saraswathy A, et al. Antibacterial activity of luteoforol from Bridelia crenulata. Fitoterapia 2001;72(4):409-11. View abstract.

Sueyoshi E, Liu H, Matsunami K, et al. Bridelionosides A-F: Megastigmane glucosides from Bridelia glauca f. balansae. Phytochemistry 2006;67(22):2483-93. View abstract.

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Theophile D, Laure NE, Benoit NT, et al. Antinociceptive and anti-inflammatory effects of the ethyl acetate stem bark extract of Bridelia scleroneura (Euphorbiaceae). Inflammopharmacology 2006;14(1-2):42-7. View abstract.