Breast cancer clinical trials are research programs designed to evaluate new medical treatments, drugs, or devices for the treatment of breast cancer. Clinical trials are designed to test the safety and efficacy of new treatments as well as assess potential side effects. Clinical trials also compare new treatment to existing treatments to determine if it's any better. There are many important questions to ask your doctor before taking part in a breast cancer clinical trial. Read more: Breast Cancer Clinical Trials Article
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Related Disease Conditions
Cancer is a disease caused by an abnormal growth of cells, also called malignancy. It is a group of 100 different diseases, and is not contagious. Cancer can be treated through chemotherapy, a treatment of drugs that destroy cancer cells.
Breast Cancer in Men
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The breast, or mammary gland is made up of lobules, milk producing glands, and a system of ducts to transport milk. Both males and females have breasts. Abnormal enlargement of breasts in men is referred to as gynecomastia. In women, during pregnancy the breasts grow larger and produce milk. Common medical conditions that affect the breasts include breast cancer, breast lumps, fibrocystic changes and cysts, mastitis, and benign tumors (fibroadenomas).
Women's health is an important topic area to guide a woman through the stages of her life, as well as knowing the conditions and diseases that may occur. Educating yourself so that the transitions into different phases of life is key to a healthy, happy, and productive life.
Triple-Negative Breast Cancer
Triple-negative breast cancer is more common in Hispanic and African-American women. Signs and symptoms include a lump in the armpit or breast, nipple discharge and inversion, and changes in the breast's skin. Treatment may incorporate surgery, chemotherapy, and radiation therapy.
Male Breast Cancer
Male breast cancer accounts for 1% of all breast cancers, and most cases are found in men between the ages of 60 and 70. A man's risk of developing breast cancer is one in 1,000. Signs and symptoms include a firm mass located below the nipple and skin changes around the nipple, including puckering, redness or scaling, retraction and ulceration of the nipple. Treatment depends upon staging and the health of the patient.
What Is Usually the First Sign of Breast Cancer?
A lump in the breast or in the armpits is often the first sign of breast cancer. This may be felt while in the shower. There may or may not be changes in the structure of the breast. Other early signs include changes in breast skin, breast pain and others.
Inflammatory Breast Cancer
Inflammatory breast cancer is an accelerated form of breast cancer that is not usually detected by mammogram or ultrasound. Symptoms of inflammatory breast cancer include pain in the breast, skin change in the breast area, bruise on the breast,sudden swelling of the breast, nipple retraction or discharge, and swelling of the lymph nodes.
Breast cancer is an invasive tumor that develops in the mammary gland. Breast cancer is detected via mammograms, breast self-examination (BSE), biopsy, and specialized testing on breast cancer tissue. Treatment of breast cancer may involve surgery, radiation, hormone therapy, chemotherapy, and targeted therapy. Breast cancer risk may be lowered by managing controllable risk factors. What you should know about breast cancer Breast cancer is the most common cancer among American women.One in every eight women in the United States develops breast cancer.There are many types of breast cancer that differ in their capability of spreading (metastasize) to other body tissues.The causes of breast cancer are unknown, although medical professionals have identified a number of risk factors.There are many different types of breast cancer.Breast cancer symptoms and signs includea lump in the breast or armpit,bloody nipple discharge,inverted nipple,orange-peel texture or dimpling of the breast's skin (peau d'orange),breast pain or sore nipple,swollen lymph nodes in the neck or armpit, anda change in the size or shape of the breast or nipple.Breast cancer can also be symptom free, which makes following national screening recommendations an important practice.Breast cancer is diagnosed during a physical exam, by a self-exam of the breasts, mammography, ultrasound testing, and biopsy.Treatment of breast cancer depends on the type of cancer and its stage (0-IV) and may involve surgery, radiation, or chemotherapy.
What Is the Difference Between a Radical Mastectomy and Modified Radical Mastectomy?
In a radical mastectomy, the entire breast tissue along with the nipple, covering skin, lymph nodes (filter organs for harmful substances) in the armpit and chest wall muscle under the breast is removed. It is known as a standard treatment for breast cancer. In a modified radical mastectomy (MRM), the entire breast is removed, including the skin, areola (surrounding the nipple), nipple and most armpit lymph nodes. The underlying chest wall muscles (the pecs) will be left intact. Additionally, the skin covering the chest wall may or may not be removed.
Can Fibroadenomas Turn Into Breast Cancer?
A fibroadenoma is the most common type of benign, non-cancerous lump of the breast. Although it is rare, complex fibroadenomas and phyllodes tumors have a chance to develop into malignant breast cancer.
Breast Cancer Prevention
Lifestyle changes, a healthy antioxidant-rich diet, exercise, and weight reduction can help reduce a woman's risk of developing breast cancer. It's important to be aware of how risk factors such as family history, lifestyle factors, breast conditions, radiation therapy, and hormonal factors may influence your chances of developing breast cancer. Mammography and breast self-examinations are crucial steps in breast cancer prevention.
Paget Disease of the Breast (Paget's Disease of the Nipple)
Paget's disease is a rare form of cancer that forms in or around the nipple and frequently coexists with breast cancer. The exact cause of Paget's disease is unknown. Symptoms and signs include redness, scaling, and flaking of the nipple skin. A biopsy and imaging studies are needed to diagnose the disease. Treatment may include surgery, radiation, and adjuvant therapy.
What Are The Five Warning Signs Of Breast Cancer?
The majority of breast cancer patients first seek diagnosis because of a lump on the breast. This is one of the five warning signs of breast cancer. Others include changes in the nipple, changes in the breast skin and other symptoms.
Breast Cancer Facts
Breast cancer is the most common non-skin cancer of American women, but it can also occur in men. Every year in the U.S., there are over 266,000 new diagnoses of breast cancer. A woman has a risk of one in eight for developing breast cancer at some point during her lifetime.
Breast Cancer and Lymphedema
Lymphedema is a common chronic, debilitating condition in which excess fluid called lymph collects in tissues and causes swelling in them. It is common after a mastectomy, lumpectomy or breast cancer surgery and radiation therapy.
Breast Cancer Recurrence
Breast cancer most often recurs within the first three to five years after the initial treatment. Changes in the look, feel, or appearance of the breast may indicate breast cancer recurrence. Factors related to recurrence include tumor size, tumor grade, hormone receptor status, lymph node involvement, and oncogene expression. Treatment for recurrent breast cancer depends on the initial treatment.
What Are the Four Types of Breast Cancer?
The four most common types of breast cancer are ductal carcinoma in situ, lobular carcinoma in situ, invasive ductal carcinoma, invasive lobular carcinoma. The designations are based on the locations of the tumors, whether they have spread and where they have spread to.
What Are the Three Top Cancer Killers?
Cancer is a group of diseases that occur when abnormal cells spread uncontrollably throughout the body. The top three cancer killers are lung cancer, colorectal cancer, and breast cancer.
What Are the Risk Factors for Developing Breast Cancer?
Breast cancer refers to the uncontrolled growth of cells within the breast. The risk factors for developing breast cancer include age, genetics, family history, personal history, menstrual history, breast density, previous radiation therapy, ethnicity, body weight, physical activity level, reproductive history, alcohol consumption and hormone pill use.
Breast Cancer Treatment by Stage
Treatment of breast cancer depends upon the stage of the cancer at the time of diagnosis. Some of the various treatments include: hormone therapy, radiation therapy, surgery, chemotherapy, HER2-targeted therapy, neoadjuvant therapy, and adjuvant therapy.
What Questions Should I Ask My Doctor About Breast Cancer?
A diagnosis of breast cancer can be overwhelming, so it's important to write down all your questions before meeting with your doctor.
Breast Cancer During Pregnancy
Breast cancer occurs in about 1 in every 1,000 pregnant women. Treatment of breast cancer during pregnancy involves surgery, but it is very difficult to protect the baby from the dangerous effects of radiation and chemotherapy. It can be an agonizing to decide whether or not to undergo breast cancer treatment while one is pregnant.
Breast Cancer in Young Women
About 5% of cases of breast cancer occur in women under the age of 40 years old. Some risk factors for breast cancer in young women include a personal history of breast cancer or breast disease, family history of breast cancer, prior radiation therapy, and the presence of BRCA1/BRCA2 gene mutations. Breast self-exams, clinical breast exams, and screening mammograms may help detect breast cancer. Treatment may include surgery, chemotherapy, radiation, and hormone therapy.
Breast Cancer and Coping With Stress
Being diagnosed with breast cancer is stressful. Learning relaxation techniques, exercising, eating well, getting adequate sleep, receiving psychotherapy, and maintaining a positive attitude can help you cope. Creating documents, such as an advance directive, living will, and durable power of attorney will outline your wishes in the event that you are no longer able to make decisions regarding your care.
How Can You Detect Breast Cancer Early?
Breast cancer develops from the cells of the breasts and can spread to other parts of the body (metastasis). It is one of the most common cancers diagnosed in women in the United States. A lump in the breast or armpit is often the first sign. Treatment success depends largely on early detection.
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Treatment & Diagnosis
Medications & Supplements
- Monoclonal Antibodies
- cyclophosphamide (Cytoxan)
- Side Effects of Femara (letrozole)
- Herceptin (trastuzumab)
- Side Effects of Cytoxan (cyclophosphamide)
- Side Effects of Taxotere (docetaxel)
- Side Effects of Megace (megestrol)
- Side Effects of Ibrance (palbociclib)
- Vijoice (alpelisib)
- Side Effects of Arimidex (anastrozole)
- Zoladex (goserelin acetate)
- Faslodex (fulvestrant) Injection
- Side Effects of Soltamox (tamoxifen)
- Side Effects of Xeloda (capecitabine)
- Side Effects of Herceptin (trastuzumab)
- Nerlynx (neratinib)
- Side Effects of Perjeta (pertuzumab)
- Abraxane (paclitaxel protein-bound particles)
- Side Effects of Tykerb (lapatinib)
- Lynparza (olaparib)
- Verzenio (abemaciclib)
- eribulin mesylate (Halaven)
- pertuzumab (Perjeta)
- Side Effects of Proleukin (aldesleukin)
- Side Effects of Halaven (eribulin mesylate)
- Ibrance (palbociclib)
- Kisqali (ribociclib)
- Lapatinib (Tykerb)
- Enhertu (fam-trastuzumab deruxtecan-nxki)
- Margenza (margetuximab-cmkb)
- Kadcyla (ado-trastuzumab emtansine)
Prevention & Wellness
- How Did the Pandemic Affect Cancer Clinical Trials?
- Who's Most Likely to Join a Clinical Trial?
- Can Women With Early Breast Cancer Skip Post-Op Radiation?
- FDA Approves Trodelvy for Metastatic Triple-Negative Breast Cancer
- It's Tough for Clinical Trial Participants to Learn Results
- Too Few Patients Enrolling in Cancer Trials
- Despite Rise in New Cases, Breast Cancer Deaths Continue to Fall
- AHA News: Scientists Find Biological Link Between High Blood Pressure and Breast Cancer
- U.S. Task Force Updates Breast Cancer Gene Testing Recommendations
- Early Risers May Be a Little Less Likely to Get Breast Cancer
- Experimental Drug Helps Women With Deadly Type of Breast Cancer
- Clinical Trials Balance Out Urban, Rural Cancer Survival Rates
- Breast Cancer Drug Promising in Phase 3 Trial
- Breakthrough Therapy Seems to Rid Woman of Advanced Breast Cancer
- Experimental Drug Shows 'Modest' Benefit in Slowing Advanced Breast Cancer
- Gene Test May Allow Many With Early Breast Cancer to Avoid Chemo
- Breast Cancer Patients May Shorten Herceptin Regimen: Study
- Breast Cancer Screening Guidelines May Miss Minorities
- 'Freezing' Technique May Work for Some Women With Early Breast Cancer
- Still Too Few Minority Participants in U.S. Clinical Trials, Study Finds
- New Treatments Target Advanced Breast Cancer