- What other names is Black Mulberry known by?
- What is Black Mulberry?
- How does Black Mulberry work?
- Are there safety concerns?
- Are there any interactions with medications?
- Dosing considerations for Black Mulberry.
Morera Negra, Morus nigra, Mulberry, Mûrier Noir, Purple Mulberry.
Black mulberry is a plant. The ripe berry and root bark are used to make medicine.
Insufficient Evidence to Rate Effectiveness for...
- Rhinitis (runny nose).
- Other conditions.
Black mulberry fruit contains pectin, which might act as a laxative to help stool pass through the bowels.
There isn't enough information to know whether or not black mulberry is safe.
Special Precautions & Warnings:Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking black mulberry if you are pregnant or breast-feeding. Stay on the safe side and avoid use.
Surgery: Black mulberry seems to lower blood sugar levels. It might interfere with blood sugar control during and after surgery. Stop using black mulberry at least 2 weeks before a scheduled surgery.
Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Some medications are changed and broken down by the liver. Black mulberry might slow down how quickly the liver breaks down some medications. Taking black mulberry along with some medications that are broken down by the liver might increase the effects and side effects of these medications. Before taking black mulberry, talk to your healthcare provider if you are taking any medications that are changed by the liver.
Medications for diabetes (Antidiabetes drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Black mulberry leaves might lower blood sugar. Diabetes medications are also used to lower blood sugar. Taking black mulberry leaves along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.
Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
The appropriate dose of black mulberry for use as treatment depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for black mulberry. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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Rabijns, A., Barre, A., Van Damme, E. J., Peumans, W. J., De Ranter, C. J., and Rouge, P. Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose. FEBS J 2005;272(14):3725-3732. View abstract.
Rouge, P., Peumans, W. J., Barre, A., and Van Damme, E. J. A structural basis for the difference in specificity between the two jacalin-related lectins from mulberry (Morus nigra) bark. Biochem Biophys.Res Commun. 4-25-2003;304(1):91-97. View abstract.
Singh, T., Wu, J. H., Peumans, W. J., Rouge, P., Van Damme, E. J., and Wu, A. M. Recognition profile of Morus nigra agglutinin (Morniga G) expressed by monomeric ligands, simple clusters and mammalian polyvalent glycotopes. Mol Immunol. 3-30-2006. View abstract.
Wu, A. M., Wu, J. H., Singh, T., Chu, K. C., Peumans, W. J., Rouge, P., and Van Damme, E. J. A novel lectin (Morniga M) from mulberry (Morus nigra) bark recognizes oligomannosyl residues in N-glycans. J Biomed.Sci 2004;11(6):874-885. View abstract.