- Side Effects
- Drug Interactions
- Pregnancy & Breastfeeding
- What Else to Know
Generic Name: bitolterol mesylate
Brand Name: Tornalate (discontinued)
Drug Class: beta-2-adrenergic receptor agonists
What is bitolterol mesylate, and what is it used for?
Asthma is a disorder of breathing in which there is narrowing of the airways that carry air to the lungs including the bronchi. This narrowing is caused by muscle spasm and inflammation within the airways. Bitolterol relaxes the smooth muscles surrounding these airways, increasing the diameter and thus easing the flow of air through the airways.
Bitolterol probably does not affect inflammation in the lung either with asthma or other inflammatory lung disorders such as bronchitis. Nevertheless, if spasm of the airways occurs because of bronchitis, bitolterol may be useful therapy for the asthmatic component of the illness. Bitolterol is unique in that it is a "prodrug." It must first be converted by the body into its active form. Bitolterol has a rapid onset of action (2-5 minutes), and its effects may last up to 6-8 hours.
The FDA approved bitolterol in December 1984.
- Do not administer bitolterol mesylate to children, as its safety for use in children under the age of 12 has not been established.
What are the side effects of bitolterol mesylate?
Side effects of bitolterol include:
- fast heart rate,
- elevated blood pressure,
- heartburn, and
Rare side effects of bitolterol include:
Worsening of diabetes and lowering of potassium have also been reported. In rare patients, inhaled bitolterol can paradoxically precipitate life-threatening bronchospasm.
What is the dosage for bitolterol mesylate?
- The recommended adult dose for treating asthma is 2 inhalations every 8 hours.
- Maximum dose is 2 inhalations every 4 hours or 3 inhalations every 6 hours.
- This drug was not approved for use in children under 12 years old.
Which drugs interact with bitolterol mesylate?
- Tricyclic antidepressants (for example, amitriptyline [Elavil, Endep]), monoamine oxidase inhibitors (for example, tranylcypromine) should not be combined with bitolterol because of their additive effects on the vascular system (increased blood pressure, heart rate, etc.). A period of two weeks should elapse between treatment with bitolterol and tricyclic antidepressants or monoamine oxidase inhibitors.
- Use of bitolterol with other stimulant medications is discouraged because of their combined effects on heart rate, blood pressure, and the potential for causing chest pain in patients with underlying coronary heart disease.
- Beta-blockers, for example, propranolol (Inderal, Inderal LA), block the effect of bitolterol and may induce bronchospasm in asthmatics. Bitolterol may cause hypokalemia (low potassium). Therefore, combining bitolterol with loop diuretics, for example, furosemide (Lasix), which lowers potassium levels in the blood, may increase the likelihood of hypokalemia.
Pregnancy and breastfeeding
What else should I know about bitolterol mesylate?
Do I need a prescription for bitolterol mesylate?
What preparations of bitolterol mesylate are available?
- Inhaler: 0.37 mg/Inhalation; Solution for Inhalation: 0.2%
How should I keep bitolterol mesylate stored?
- Bitolterol should be stored at room temperature, 15 C to 30 C (59 F to 86 F).
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Bitolterol mesylate is a drug prescribed for the treatment of bronchospasms due to asthma and other respiratory illnesses. Side effects of bitolterol include nervousness, tremor, headache, palpitations, fast heart rate, elevated blood pressure, nausea, dizziness, heartburn, and nosebleeds. Bitolterol mesylate is not for use in children under the age of 12. Consult your doctor if pregnant or breastfeeding.
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Related Disease Conditions
An allergy refers to a misguided reaction by our immune system in response to bodily contact with certain foreign substances. When these allergens come in contact with the body, it causes the immune system to develop an allergic reaction in people who are allergic to it. It is estimated that 50 million North Americans are affected by allergic conditions. The parts of the body that are prone to react to allergies include the eyes, nose, lungs, skin, and stomach. Common allergic disorders include hay fever, asthma, allergic eyes, allergic eczema, hives, and allergic shock.
COPD vs. Asthma (Differences and Similarities)
COPD (chronic obstructive pulmonary disease) and asthma both have common symptoms like coughing, wheezing, shortness of breath, and a tight feeling in the chest. COPD is caused by tobacco smoking, while asthma is caused by your inherited genetic makeup and their interactions with the environment. Risk factors for asthma are obesity, exposure to cigarette smoke (even secondhand smoke), and personal history of hay fever. There is no cure for either disease, but symptoms can be managed with medication. A person with asthma has a better prognosis and life expectancy than someone with COPD.
Fragrances and preservatives in cosmetics may cause allergic reactions in some people. Symptoms include redness, itching, and swelling after the product comes in contact with the person's skin. Treatment typically involves the use of over-the-counter cortisone creams.
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Milk allergy reactions may cause immediate or delayed symptoms. Learn to spot the signs and what foods to avoid if you have a dairy allergy.
Why Won’t My Allergy Symptoms Go Away?
Allergies happen when your body's immune system reacts to certain substances as though they are harmful. Allergy symptoms may not go away unless you avoid your triggers, stick to your medications, find the right combination of medications, and consider surgery.
Asthma is a condition in which hyperreactive airways constrict and result in symptoms like wheezing, coughing, and shortness of breath. Causes of asthma include genetics, environmental factors, personal history of allergies, and other factors. Asthma is diagnosed by a physician based on a patient's family history and results from lung function tests and other exams. Inhaled corticosteroids (ICS) and long-acting bronchodilators (LABAs) are used in the treatment of asthma. Generally, the prognosis for a patient with asthma is good. Exposure to allergens found on farms may protect against asthma symptoms.
Eye allergy (or allergic eye disease) are typically associated with hay fever and atopic dermatitis. Medications and cosmetics may cause eye allergies. Allergic eye conditions include allergic conjunctivitis, conjunctivitis with atopic dermatitis, vernal keratoconjunctivitis, and giant papillary conjunctivitis. Dry eye, tear-duct obstruction, and conjunctivitis due to infection are frequently confused with eye allergies. Eye allergies may be treated with topical antihistamines, decongestants, topical mast-cell stabilizers, topical anti-inflammatory drugs, systemic medications, and allergy shots.
Asthma: Over the Counter Treatment
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Can Asthma Damage Your Lungs?
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Cold, Flu, Allergy Treatments
Before treating a cold, the flu, or allergies with over-the-counter (OTC) medications, it's important to know what's causing the symptoms, which symptoms one wishes to relieve, and the active ingredients in the OTC product. Taking products that only contain the medications needed for relieving your symptoms prevents ingestion of unnecessary medications and reduces the chances of side effects.
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What Is the Treatment for Asthmatic Bronchitis?
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There are two types of asthma medications: long-term control with anti-inflammatory drugs and quick relief from bronchodilators. Asthma medicines may be inhaled using a metered-dose inhaler or nebulizer or they may be taken orally. People with high blood pressure, diabetes, thyroid disease, or heart disease shouldn't take OTC asthma drugs like Primatene Mist and Bronkaid.
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Drug Allergy (Medication Allergy)
Drug or medication allergies are caused when the immune system mistakenly creates an immune response to a medication. Symptoms of a drug allergic reaction include hives, rash, itchy skin or eyes, dizziness, nausea, diarrhea, fainting, and anxiety. The most common drugs that people are allergic to include penicillins and penicillin type drugs, sulfa drugs, insulin, and iodine. Treatment may involve antihistamines or corticosteroids. An EpiPen may be used for life-threatening anaphylactic symptoms.
Can You Eat Avocado if You Have a Nut Allergy?
Since avocado is classified as a fruit and not a tree nut, you should be able to eat avocados even if you have a nut allergy. However, some studies have shown that avocados have similar proteins as chestnuts. So if you’re allergic to chestnuts, you may have to avoid avocados.
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Avoiding allergy triggers at home is one of the best ways to prevent allergy symptoms. Controlling temperature, humidity, and ventilation are a few ways to allergy-proof the home. Cleaning, vacuuming, and using HEPA air filters also helps control allergies.
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How Long Does Asthmatic Bronchitis Last?
The duration of the disease usually depends on the patient’s overall health and age. In patients with acute bronchitis symptoms may last less than 10 days. In patients with severe asthmatic bronchitis, the symptoms are recurrent and usually last between 30 days to even 2 years with flares and remissions.
What Are the Four Types of Asthma?
Asthma is a chronic inflammatory disease of the airways (bronchi). Bronchi generally allow for the passage of air in and out of the lungs. In asthma, these airways develop hypersensitivity, inflammation, and narrowing. This causes difficulty in breathing. The four types are mild intermittent, mild persistent, moderate persistent and severe persistent.
Asthma in Children
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Are Food Allergies Passed Down Genetically?
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Though there is some overlap in allergy and COVID-19 signs and symptoms there are also significant differences. Symptoms that they have in common include headache, fatigue, tiredness, shortness of breath, wheezing, and sore throat. Fever does not occur with allergies but is one of the defining symptoms of COVID-19 infections.
What Are Typical Allergy Symptoms?
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Exercise-induced asthma is asthma triggered by vigorous exercise. Symptoms include coughing, shortness of breath, chest tightness, wheezing, and fatigue while exercising. Preventing exercise-induced asthma attacks involves using inhaled medicines before exercising, performing warm-up exercises and cooling down afterward, avoiding exercising outdoors when pollen counts are high, restricting exercise when you have a viral infection, and wearing a mask over your nose and mouth when exercising in cold weather.
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Do Allergy Desensitization Shots Work?
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Can You Exercise With Exercise-Induced Asthma?
You can continue exercise and normal physical activity even after being diagnosed with exercise-induced asthma (EIA).
What Is the Best Treatment for Asthma?
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Typical seasonal allergy symptoms include a stuffy or runny nose, sneezing, coughing, watery eyes, congestion, and a sore throat.
What Are the Symptoms of E-Asthma?
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How Do You Get Tested for Food Allergies?
If you develop symptoms of a food allergy, your doctor will have you undergo a skin test or blood test to determine which foods you are allergic to.
What Foods Cause Oral Allergy Syndrome?
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Is Food Intolerance the Same as Food Allergy?
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What Class Is Severe Asthma?
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What Is Severe Asthma?
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