- Birth Control Pills vs. Patch: What's the difference?
- What are Birth Control Pills? What is the Patch?
- What are the side effects of birth control pills and the patch?
- What is the dosage for birth control pills vs. the patch?
- What drugs interact with birth control pills and the patch?
- Are birth control pills and the patch safe to use while pregnant or breastfeeding?
Birth Control Pills vs. Patch: What's the difference?
- Birth control pills (oral contraceptives) and norelgestromin/ethinyl estradiol transdermal patches (Ortho Evra) are methods of birth control used to prevent pregnancy.
- Side effects of birth control pills and the patch that are similar include nausea, headache, breast tenderness/enlargement, missed/irregular bleeding, and breakthrough bleeding (spotting).
- Side effects of birth control pills that are different from the patch include weight gain, scanty menstrual periods, and mood changes.
- Side effects of that the patch are different from birth control pills include vomiting, redness/irritation at the application site, dizziness, vaginal discomfort/irritation, increased vaginal discharge, acne, or stomach cramping/bloating may occur.
What are Birth Control Pills? What is the Patch?
Birth control pills (oral contraceptives) are a method of birth control used to prevent pregnancy. Birth control pills are hormonal preparations that may contain combinations of the hormones estrogen and progestin or progestin alone. Combinations of estrogen and progestin prevent pregnancy by inhibiting the release of the hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland in the brain. LH and FSH play key roles in the development of the egg and preparation of the lining of the uterus for implantation of the embryo. Progestin also makes the uterine mucus that surrounds the egg more difficult for sperm to penetrate and, therefore, for fertilization to take place. In some women, progestin inhibits ovulation (release of the egg).
Norelgestromin/ethinyl estradiol transdermal patch is a combination of 2 hormones (an estrogen and a progestin) and is used to prevent pregnancy. It works mainly by preventing the release of an egg (ovulation) during your menstrual cycle. It also can work by making vaginal fluid thicker to help prevent sperm from reaching an egg (fertilization) and by changing the lining of the uterus (womb) to prevent attachment of a fertilized egg. If a fertilized egg does not attach to the uterus, it passes out of the body. The total amount of estrogen received when using the patch is higher than the amount from most birth control pills, which may increase the risk for blood clots or other side effects from the birth control patch compared to the pill. If you weigh more than 198 pounds (90 kilograms), this patch may not work as well for you.

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Sex-Drive Killers: The Causes of Low Libido See SlideshowWhat are the side effects of birth control pills and the patch?
Birth control pills
The most common side effects of the birth control pills include nausea, headache, breast tenderness, weight gain, irregular bleeding, and mood changes. These side effects often subside after a few months' use. Scanty menstrual periods or breakthrough bleeding may occur but are often temporary, and neither side effect is serious. Women with a history of migraines may notice an increase in migraine frequency. On the other hand, women whose migraines are triggered by fluctuations in their own hormone levels may notice improvement in migraines with oral contraceptive use because of the more uniform hormone levels during oral contraceptive use.
Uncommonly, oral contraceptives may contribute to increased blood pressure, blood clots, heart attack, and stroke. Women who smoke, especially those over 35, and women with certain medical conditions, such as a history of blood clots or breast or endometrial cancer, may be advised against taking oral contraceptives, as these conditions can increase the adverse risks of oral contraceptives.
Ortho Evra
WARNING
Ortho Evra is intended to prevent pregnancy. It does not protect against HIV (AIDS) or other sexually transmitted diseases such as chlamydia, genital herpes, genital warts, gonorrhea, hepatitis B, and syphilis.
The most common side effects of Ortho Evra include:
• nausea and vomiting,
• breast symptoms,
• headache,
• menstrual cramps, and
• abdominal pain.
In addition, change in appetite, nervousness, depression, dizziness, loss of scalp hair, rash, and vaginal infections may occur.
Skin Irritation
Skin irritation, redness or rash may occur at the site of application. If this occurs, the patch may be removed and a new patch may be applied to a new location until the next Change Day. Single replacement patches are available from pharmacies.
Irregular vaginal bleeding or spotting may occur while you are using Ortho Evra. Irregular bleeding may vary from slight staining between menstrual periods to breakthrough bleeding which is a flow much like a regular period. Irregular bleeding may occur during the first few months of contraceptive patch use but may also occur after you have been using the contraceptive patch for some time. Such bleeding may be temporary and usually does not indicate any serious problems. It is important to continue using your contraceptive patches on schedule. If the bleeding occurs in more than a few cycles or lasts for more than a few days, talk to your health care professional.
Problems Wearing Contact Lenses
If you wear contact lenses and notice a change in vision or an inability to wear your lenses, contact your health care professional.
Fluid Retention or Raised Blood Pressure
Hormonal contraceptives, including the contraceptive patch, may cause edema (fluid retention) with swelling of the fingers or ankles and may raise your blood pressure. If you experience fluid retention, contact your health care professional.
A spotty darkening of the skin is possible, particularly of the face. This may persist after use of hormonal contraceptives is discontinued.
What is the dosage for birth control pills vs. the patch?
Birth control pills
Many of the birth control pills come in easy-to-use dispensers in which the day of the week or a consecutive number (1, 2, 3, etc.) is written on the dispenser with a corresponding tablet for each day or number.
For example, some Ortho-Novum dispensers are labeled "Sunday" next to the first tablet. Thus, the first tablet is to be taken on the first Sunday after menstruation begins (the first Sunday following the first day of a woman's period). If her period begins on Sunday, the first tablet should be taken on that day.
For birth control pills that use consecutive numbers, the first tablet (#1) is taken on the first day of the menstrual period (the first day of bleeding). Tablet #2 is taken on the second day and so on.
Still other packages instruct women to begin on day five of the cycle. For such products, women count from day one of their menstrual cycle (day one is the first day of bleeding). On the fifth day, the first tablet is taken. Tablets then are taken daily.
Most birth control pills are packaged as 21-day or 28-day units. For 21-day packages, tablets are taken daily for 21 days. This is followed by a seven-day period during which no birth control pills are taken. Then the cycle repeats.
For the 28-day units, tablets containing medication are taken for 21 consecutive days, followed by a seven-day period during which placebo tablets (containing no medication) are taken.
Newer formulations with 24 days of hormone pills and only four days of placebo pills are now available, as are continuous or extended-cycle oral contraceptive regimens, in which only active hormone pills are taken. Extended-cycle preparations include seven-day intervals of placebo pills to be taken approximately every three months.
Women just starting to take birth control pills should use additional contraception for the first seven days of use because pregnancy may occur during this period.
If women forget to take tablets, pregnancy may result. If a single tablet is forgotten, it should be taken as soon as it is realized that it is forgotten. If more than one tablet is forgotten, the instructions that come with the packaging should be consulted, or a physician or pharmacist should be called.
Ortho Evra
Ortho Evra keeps you from becoming pregnant by transferring hormones to your body through your skin. The patch must stick securely to your skin in order for it to work properly. This method uses a 28 day (four week) cycle. You should apply a new patch each week for three weeks (21 total days).
You should not apply a patch during the fourth week. Your menstrual period should start during this patch-free week. Every new patch should be applied on the same day of the week. This day will be your ‘Patch Change Day.’
For example, if you apply your first patch on a Monday, all of your patches should be applied on a Monday.
You should wear only one patch at a time. On the day after week four ends, you should begin a new four week cycle by applying a new patch.
What drugs interact with birth control pills and the patch?
Birth control pills
Estrogens can inhibit the metabolism (elimination) of cyclosporine, resulting in increased cyclosporine blood levels. Such increased blood levels can result in kidney and/or liver damage. If this combination cannot be avoided, cyclosporine concentrations can be monitored, and the dose of cyclosporine can be adjusted to assure that its blood levels do not become elevated.
Estrogens appear to increase the risk of liver disease in patients receiving dantrolene (Dantrium) through an unknown mechanism. Women over 35 years of age and those with a history of liver disease are especially at risk.
Estrogens increase the liver's ability to manufacture clotting factors. Because of this, patients receiving warfarin (Coumadin) need to be monitored for loss of anticoagulant (blood thinning) effect if an estrogen is begun.
A number of medications, including some antibiotics and antiseizure medications, can decrease the blood levels of oral contraceptive hormones, but an actual decrease in the effectiveness of the oral contraceptive has not been convincingly proven. Nonetheless, because of this theoretical possibility, some physicians recommend backup contraceptive methods during antibiotic use. Examples of medications that increase the elimination of estrogens include
• carbamazepine (Tegretol),
• phenobarbital,
• phenytoin (Dilantin),
• primidone (Mysoline),
• rifampin (Rifadin),
• rifabutin (Mycobutin), and
• ritonavir (Norvir).
Birth control pills with higher concentrations of estrogen or alternative forms of contraception may be necessary in women using those medications.
Ortho Evra
Certain drugs may interact with hormonal contraceptives, including Ortho Evra, to make them less effective in preventing pregnancy or cause an increase in breakthrough bleeding. Such drugs include rifampin, drugs used for epilepsy such as barbiturates (for example, phenobarbital), anticonvulsants such as topiramate (TOPAMAX), carbamazepine (Tegretol is one brand of this drug), phenytoin (Dilantin is one brand of this drug), phenylbutazone (Butazolidin is one brand), certain drugs used in the treatment of HIV or AIDS, and possibly certain antibiotics. Tetracycline has been shown not to interact with Ortho Evra. Pregnancies and breakthrough bleeding have been reported by users of combined hormonal contraceptives who also used some form of St. John’s Wort. As with all prescription products, you should notify your health care professional of any other medications you are taking. You may need to use a barrier contraceptive when you take drugs that can make Ortho Evra less effective.
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Are birth control pills and the patch safe to use while pregnant or breastfeeding?
Birth control pills
Use of birth control pills during lactation has been associated with decreased milk production, decreased infant weight gain, and decreased nitrogen and protein content of milk. The amount of estrogen consumed by an infant whose mother takes a standard dose of birth control pills is considered to be the same as from a lactating woman who is not taking birth control pills, and side effects have not been reported. Using a progestin-only product is most often recommended during lactation if birth control pills are to be used during this period. The American College of Obstetrics and Gynecology (ACOG) recommends delaying taking combined estrogen-progestin contraceptives until at least six weeks postpartum, while the World Health Organization (WHO) recommends delaying the initiation of combined contraceptives until six months.
Ortho Evra
There is no conclusive evidence that hormonal contraceptive use causes birth defects when taken accidentally during early pregnancy. Previously, a few studies had reported that oral contraceptives might be associated with birth defects, but these findings have not been seen in more recent studies. Nevertheless, hormonal contraceptives, including Ortho Evra, should not be used during pregnancy.
If you are breast-feeding, consult your health care professional before starting Ortho Evra. Hormonal contraceptives are passed on to the child in the milk. A few adverse effects on the child have been reported, including yellowing of the skin (jaundice) and breast enlargement. In addition, combination hormonal contraceptives 52 may decrease the amount and quality of your milk. If possible, do not use combination hormonal contraceptives such as Ortho Evra.
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Summary
Birth control pills (oral contraceptives) and norelgestromin/ethinyl estradiol transdermal patches (Ortho Evra) are methods of birth control used to prevent pregnancy. Side effects of birth control pills and the patch that are similar include nausea, headache, breast tenderness/enlargement, missed/irregular bleeding, and breakthrough bleeding (spotting).
Multimedia: Slideshows, Images & Quizzes
-
Choosing Your Birth Control Method
Which birth control option is right for you? Discover birth control methods such as birth control pills, birth control shot,...
-
Birth Control Quiz: Test Your Medical IQ
What is the best form of birth control? Take this quiz to find out about hormonal, surgical, barrier, and natural methods!
Related Disease Conditions
-
Birth Control Options
Birth control is available in a variety of methods and types. The method of birth control varies from person to person, and their preferences to either become pregnant or not. Examples of barrier methods include barrier methods (sponge, spermicides, condoms), hormonal methods (pill, patch), surgical sterilization (tubal ligation, vasectomy), natural methods, and the morning-after pill. Side effects and risks of each birth control option should be reviewed before using any birth control method.
-
Does the Pill Stop Your Period?
Oral contraceptive pills (OCPs) or birth control pills or the pill is a hormonal pill that is used to prevent pregnancy. Because the pills alter your hormone levels, it is possible to temporarily stop or prevent your period with continuous use of any birth control pill.
-
Birth Control Pill vs. Depo-Provera Shot
Birth control pills (oral contraceptives) and the Depo-Provera shot are two hormonal methods of birth control. Both methods work by changing the hormone levels in your body, which prevents pregnancy, or conception. Differences between "the pill" and "the shot." Birth control pills are available as combination pills, which contain the hormones estrogen and progestin, or mini-pills that only contain progestin. In comparison to the Depo-Provera injection, which prevents pregnancy for three consecutive months. Both methods of birth control are very effective in preventing pregnancy. Both the combination pill (if you take them as directed) and shot are up to 99% effective in preventing pregnancy. While the mini-pill is only about 95% effective in preventing pregnancy. Both methods cause weight gain, and have other similar side effects like breast pain, soreness or tenderness, headaches, and mood changes. They may lead to decreased interest in sex in some women. There are differences between the other side effects of these methods (depending upon the method) that include breakthrough bleeding or spotting, acne, depression, fatigue, and weakness. Both oral contraceptives and the Depo-Provera shot have health risks associated with them, such as, heart attack, stroke, blood clots, and cervical cancer. Birth control pills appear to increase the risk of cervical cancer. Talk with your OB/GYN or other doctor or health care professional about which birth control method is right for you.
-
Can You Lose Weight While on the Birth Control Pill?
It is possible to lose weight while on the birth control pill, but every woman's body is different and reacts differently to hormones. Eating a sensible diet and adopting a regular workout regimen will help you maintain a healthy weight.
-
DVT and Birth Control Pills (Oral Contraceptives)
Deep vein thrombosis (DVT) is a blood clot that has traveled deep into the veins of the arm, pelvis, or lower extremities. Oral contraceptives or birth control pills can slightly increase a woman's risk for developing blood clots, including DVT. DVT symptoms and signs in the leg include leg or calf pain, redness, swelling, warmth, or leg cramps, and skin discoloration. If a blood clot in the leg is not treated, it can travel to the lungs, which can cause a pulmonary embolism (blood clot in the lung) or post-thrombotic syndrome, both of which can be fatal if not treated immediately. Increased risk factors for DVT and birth control pills include over 40 years of age, family history, smoking, and obesity. Other medical problems that increase the risks of blood clots, for example, lung or heart disease, or inflammatory bowel disease or IBD (Crohn's disease and ulcerative colitis (UC). Other options for preventing pregnancy include IUDs, birth control shots, condoms, diaphragms, and progestin-only oral contraceptives.
-
Is It OK To Skip the 7-Day Break on the Pill?
There seems to be no additional risks associated with using the pill to suppress the seven-day break (beyond the health risks already linked to hormonal pills or devices).
Treatment & Diagnosis
Medications & Supplements
- Birth Control Pills (Oral Contraceptives)
- Birth control pills (oral contraceptives) vs. Plan B (levonorgestrel)
- Birth Control Pills vs. Nuvaring
- Birth Control Pills vs. Condoms
- What Are Hormonal Methods of Contraception?
- Birth Control Pills (Oral Contraceptive) vs. Depo-Provera (medroxyprogesterone injection)
- What Are the Barrier Methods of Contraception?
- mifepristone
- What Are Intrauterine Devices?
- norelgestromin/ethinyl estradiol patch - transdermal, Ortho Evra
Prevention & Wellness
- Birth Control Coverage Opt-Out Finalized by Trump Administration
- Newer Birth Control Pills Tied to Lower Odds for Ovarian Cancer
- Fewer American Teens Having Sex, Most Using Birth Control
- Bayer Stops U.S. Sale of Essure Birth Control Implant
- Birth Control Pills Recalled Over Potential Pregnancy Risk
- Male Birth Control Pill Shows Early Promise
- Hormonal Birth Control Won't Raise Depression Risk: Study
- Birth Control Pill Tied to Slight Rise in Breast Cancer Risk
- Birth Control Pills Recalled Due to Danger of Unintended Pregnancy
- Male Birth Control in a Shot: Promising, But More Work Needed
- Put Birth Control in Place Right After Childbirth
- Obese Women on Birth Control Pills May Face Higher Risk of Rare Stroke
- Study Ties Essure Birth Control Implant to Greater Need for Reoperation
- Obese Teens Less Likely to Use Birth Control
- Pediatricians Endorse IUDs, Implants for Teen Birth Control
- Majority of Americans Support Obamacare Birth Control Provision: Survey
- Male Birth Control Shows Promise in Mice
- 1 in 3 Young U.S. Women Uses 'Withdrawal' for Birth Control
- IUDs Increasingly Popular Form of Birth Control
- 2 in 5 Women Don't Use Birth Control
- Progress Toward Male Birth Control Pill?
- 1 Million Birth Control Pill Packs Recalled
- No More Co-pay for Birth Control
- FDA Investigates Newer Birth Control Pills
- Birth Control Pills Put Brakes on Women's Sex Drive
- Male Abusers Often Sabotage Birth Control With Partners
- Birth Control May Help Ward Off Bacterial Vaginosis
- Hormone Combo May Provide Reversible Male Birth Control Tool
- FDA OKs 'No-Period' Birth Control Pill
- Chewable Birth Control Available
- FDA OKs New Birth Control Pill
- Experts: Risk of Birth Control Patch Overstated
- Low-Dose Birth Control Pill May Up Heart Risk

Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Source content for Ortho Evra sections courtesy of the U.S. Food and Drug Administration
Top Birth Control Pills vs Patch ortho evra Related Articles
Barrier Methods of Birth Control Side Effects, Advantages, and Disadvantages
Many barrier methods of birth control are available for a man or woman, for example, the sponge, female and male condoms, diaphram, spermicides, male condoms, female condoms, contraceptive sponge, diaphragm, and cervical cap. Side effects, and efficacy (in preventing pregnancy) depends on the type of birth control used.
Birth Control Options
Birth control is available in a variety of methods and types. The method of birth control varies from person to person, and their preferences to either become pregnant or not. Examples of barrier methods include barrier methods (sponge, spermicides, condoms), hormonal methods (pill, patch), surgical sterilization (tubal ligation, vasectomy), natural methods, and the morning after pill. Side effects and risks of each birth control option should be reviewed prior to using any birth control method.Choosing Your Birth Control Method
Which birth control option is right for you? Discover birth control methods such as birth control pills, birth control shot, implant, patch and more. Learn about birth control side effects and effectiveness.Birth Control Pill vs. Depo-Provera Shot
Birth control pills (oral contraceptives) and the Depo-Provera shot are two hormonal methods of birth control. Both methods work by changing the hormone levels in your body, which prevents pregnancy, or conception. Differences between "the pill" and "the shot." Birth control pills are available as combination pills, which contain the hormones estrogen and progestin, or mini-pills that only contain progestin. In comparison to the Depo-Provera injection, which prevents pregnancy for three consecutive months. Both methods of birth control are very effective in preventing pregnancy. Both the combination pill (if you take them as directed) and shot are up to 99% effective in preventing pregnancy. While the mini-pill is only about 95% effective in preventing pregnancy. Both methods cause weight gain, and have other similar side effects like breast pain, soreness or tenderness, headaches, and mood changes. They may lead to decreased interest in sex in some women. There are differences between the other side effects of these methods (depending upon the method) that include breakthrough bleeding or spotting, acne, depression, fatigue, and weakness. Both oral contraceptives and the Depo-Provera shot have health risks associated with them, such as, heart attack, stroke, blood clots, and cervical cancer. Birth control pills appear to increase the risk of cervical cancer. Talk with your OB/GYN or other doctor or health care professional about which birth control method is right for you.Birth Control Pills vs. Nuvaring
Birth control pills (oral contraceptives) and Nuvaring (etonogestrel/ethinyl estradiol) are methods of birth control used to prevent pregnancy. Birth control pills are taken orally while Nuvaring is a vaginal ring inserted intravaginally.Birth control pills (oral contraceptives) vs. Plan B (levonorgestrel)
Birth control pills (oral contraceptives) and Plan B (levonorgestrel) are methods of birth control used to prevent pregnancy. Birth control pills are taken regularly to prevent pregnancy, while Plan B is emergency contraception (“the morning after pill”) used as backup contraception to prevent pregnancy when taken within 72 hours after unprotected sex or when birth control fails.Birth Control Quiz: Test Your Medical IQ
What is the best form of birth control? Take this quiz to find out about hormonal, surgical, barrier, and natural methods!Does the Pill Stop Your Period?
Oral contraceptive pills (OCPs) or birth control pills or the pill is a hormonal pill that is used to prevent pregnancy. Because the pills alter your hormone levels, it is possible to temporarily stop or prevent your period with continuous use of any birth control pill.DVT and Birth Control Pills (Oral Contraceptives)
Deep vein thrombosis (DVT) is a blood clot that has traveled deep into the veins of the arm, pelvis, or lower extremities. Oral contraceptives or birth control pills can slightly increase a woman's risk for developing blood clots, including DVT. DVT symptoms and signs in the leg include leg or calf pain, redness, swelling, warmth, or leg cramps, and skin discoloration. If a blood clot in the leg is not treated, it can travel to the lungs, which can cause a pulmonary embolism (blood clot in the lung) or post-thrombotic syndrome, both of which can be fatal if not treated immediately. Increased risk factors for DVT and birth control pills include over 40 years of age, family history, smoking, and obesity. Other medical problems that increase the risks of blood clots, for example, lung or heart disease, or inflammatory bowel disease or IBD (Crohn's disease and ulcerative colitis (UC). Other options for preventing pregnancy include IUDs, birth control shots, condoms, diaphragms, and progestin-only oral contraceptives.Hormonal Methods of Birth Control
There are several different hormonal methods of birth control. The hormones can be estrogen and/or progesterone. The hormones can be taken by mouth, implanted into body tissue, absorbed from a patch on the skin, injected under the skin, or placed in the vagina. Common types of hormonal birth control include: "The Pill" (oral contraceptives), injection (Depo-Provera, Lunelle), the patch (Ortho-Evra), and the vaginal ring (Nuvaring).Is It OK To Skip the 7-Day Break on the Pill?
There seems to be no additional risks associated with using the pill to suppress the seven-day break (beyond the health risks already linked to hormonal pills or devices).IUD (Intrauterine Device for Birth Control)
An IUD (intrauterine device) is a birth control method designed for a woman. The IUD is a small "T" made of molded polyethylene plastic coated with barium so that, if need be, it can be seen on X-ray.
There are two types of IUDs 1) Intrauterine contraceptive device (IUCD) including the ParaGard, Copper 7, and Mini-7; and 2) Intrauterine system (IUS) including Progestasert and Mirena.
Side effects of the IUD include spotting, infection, infertility, pelvic inflammatory disease, and heavy menstrual bleeding. Risks and complications of the IUD are miscarriage, ectopic pregnancy, pelvic inflammatory disease, and increased menstrual bleeding.
Can You Lose Weight While on the Birth Control Pill?
It is possible to lose weight while on the birth control pill, but every woman's body is different and reacts differently to hormones. Eating a sensible diet and adopting a regular workout regimen will help you maintain a healthy weight.Natural Birth Control
Natural methods of contraception are considered "natural" because they are non-mechanical and non-hormonal. Fertility awareness methods (FAMs) are based upon knowing when a woman ovulates each month. Natural methods of birth control include: the calendar rhythm, basal body temperature, mucus inspection, symptothermal, use of an ovulation indicator testing kit, withdrawal, lactational infertility, douching and urination, and abstinence.Birth Control Pills (List of Oral Contraceptives and Side Effects)
Birth control pills (oral contraceptives) are prescription medications that prevent pregnancy. Three combinations of birth control pills that contain progestin and estrogen are 1) monophasic, 2) biphasic, and 3) triphasic. Birth control pills may also be prescribed to reduce menstrual cramps or prevent anemia. Certain prescription medications may cause drug interactions. Some women experience various levels of side effects of birth control pills.Birth Control: Surgical Sterilization
Surgical sterilization is considered a permanent method of contraception. In certain cases, sterilization can be reversed, but this is not guaranteed. For this reason, sterilization is meant for men and women who do not intend to have children in the future. Types of surgical sterilization include: vasectomy, tubal ligation, STOP (selective tubal occlusion procedure), and hysterectomy.What Are the Natural Contraception Methods?
So-called “natural” contraception or birth control methods rely on behavioral and scheduling changes in your sex life, predicated on exceptional self-control skills. For these reasons, behavioral methods of birth control are the least effective available.