Bile duct cancer (cholangiocarcinoma) is a rare type of cancer that arises from cells that line the drainage system from the liver and gallbladder to the intestine. Symptoms and signs of bile duct cancer include jaundice, itching, weight loss, and abdominal pain. Physical examination, specialized blood tests, and imaging tests may be used to diagnose bile duct cancer. Treatment for bile duct cancer may include chemotherapy, radiation therapy, and photodynamic therapy. Bile duct cancer typically has a poor prognosis. Preventing liver damage may decrease the risk of developing bile duct cancer. Read more: Bile Duct Cancer (Cholangiocarcinoma) Article
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Related Disease Conditions
Cirrhosis of the liver refers to a disease in which normal liver cells are replaced by scar tissue caused by alcohol and viral hepatitis B and C. This disease leads to abnormalities in the liver's ability to handle toxins and blood flow, causing internal bleeding, kidney failure, mental confusion, coma, body fluid accumulation, and frequent infections. Symptoms include yellowing of the skin (jaundice), itching, and fatigue. The prognosis is good for some people with cirrhosis of the liver, and the survival can be up to 12 years; however the life expectancy is about 6 months to 2 years for people with severe cirrhosis with major complications.
Cancer is a disease caused by an abnormal growth of cells, also called malignancy. It is a group of 100 different diseases, and is not contagious. Cancer can be treated through chemotherapy, a treatment of drugs that destroy cancer cells.
Itch (Itching or Pruritus)
Itching can be a common problem. Itches can be localized or generalized. There are many causes of itching including infection (jock itch, vaginal itch), disease (hyperthyroidism, liver or kidney), reactions to drugs, and skin infestations (pubic or body lice). Treatment for itching varies depending on the cause of the itch.
Abdominal pain can have many causes that range from mild to severe. Some of these causes include bloating, gas, colitis, endometriosis, food poisoning, GERD, IBS (irritable bowel syndrome), ovarian cysts, abdominal adhesions, diverticulitis, Crohn's disease, ulcerative colitis, gallbladder disease, liver disease, and cancers. Signs and symptoms of the more serious causes include dehydration, bloody or black tarry stools, severe abdominal pain, pain with no urination or painful urination. Treatment for abdominal pain depends upon the cause.
Jaundice in Adults (Hyperbilirubinemia)
Jaundice or hyperbilirubinemia in adults is caused by an underlying disease or condition. Learn about when to worry about jaundice in adults, symptoms, treatment, causes, diagnosis, and prevention.
Bilirubin is a waste product of the normal breakdown of red blood cells in the liver. Normal bilirubin levels vary from lab to lab, and range from around 0.2 to 1.2 mg/dL. High levels of bilirubin can be diagnosed with a bilirubin blood test. Causes of elevated levels of bilirubin in the blood can be caused by infections, viral hepatitis, anemia, genetic diseases, and liver problems. Symptoms of elevated bilirubin levels depend on the cause; however, jaundice is a common sign. Treatment for elevated bilirubin levels depend on the cause.
Liver (Anatomy and Function)
The liver is the largest gland and organ in the body. There are a variety of liver diseases caused by liver inflammation, scarring of the liver, infection of the liver, gallstones, cancer, toxins, genetic diseases, and blood flow problems. Symptoms of liver disease generally do not occur until the liver disease is advanced. Some symptoms of liver disease include jaundice, nausea and vomiting, easy bruising, bleeding excessively, fatigue, weakness, weight loss, shortness of breath, leg swelling, impotence, and confusion. Treatment of diseases of the liver depends on the cause.
Intestinal Gas and Gas Pain
Intestinal gas and painful bloating are common. Learn about what causes gas pain and how eliminating certain foods from your diet can help relieve symptoms.
Obesity and Overweight
Get the facts on obesity and being overweight, including the health risks, causes, reviews of weight-loss diet plans, BMI chart, symptoms, causes, surgical and nonsurgical treatments, and medications.
Although a fever technically is any body temperature above the normal of 98.6 F (37 C), in practice, a person is usually not considered to have a significant fever until the temperature is above 100.4 F (38 C). Fever is part of the body's own disease-fighting arsenal; rising body temperatures apparently are capable of killing off many disease-producing organisms.
What Is the Function of Bile?
Bile juice is a digestive fluid produced by the liver. It is stored and concentrated in the gallbladder. Its main function is to convert fats in food into fatty acids, which are absorbed in the gut. Bile aids in digestion, absorption, detoxification and other processes.
Hepatitis (Viral Hepatitis A, B, C, D, E, G)
Hepatitis is most often viral, due to infection with one of the hepatitis viruses (A, B, C, D, E, F (not confirmed), and G) or another virus (such as those that cause infectious mononucleosis, cytomegalovirus disease). The main nonviral causes of hepatitis are alcohol and drugs. Many patients infected with hepatitis A, B, and C have few or no symptoms of illness. For those who do develop symptoms of viral hepatitis, the most common are flu-like symptoms including: loss of appetite, nausea, vomiting, fever, weakness, tiredness, and aching in the abdomen. Treatment of viral hepatitis is dependent on the type of hepatitis.
Tumor grade is a system used to classify cancer cells in how likely the tumor is to grow and how abnormal they look under a microscope. Tumor grade is not the same as tumor stage. A biopsy is taken to determine if the tumor is benign (non cancerous) or malignant (cancerous).
Smoking (How to Quit Smoking)
Smoking is an addiction. More than 430,000 deaths occur each year in the U.S. from smoking related illnesses. Secondhand smoke or "passive smoke" also harm family members, coworkers, and others around smokers. There are a number of techniques available to assist people who want to quit smoking.
Hepatitis C (HCV, Hep C)
Hepatitis C is an inflammation of the liver due to the hepatitis C virus (HCV), which is usually spread by blood transfusion, hemodialysis, and needle sticks, especially with intravenous drug abuse. Symptoms of chronic hepatitis include fatigue, fever, muscle aches, loss of appetite, and fever. Chronic hepatitis C may be cured in most individuals with drugs that target specific genomes of hepatitis C.
Hepatitis B (HBV, Hep B)
The hepatitis B virus (HBV, hep B) is a unique, coated DNA virus belonging to the Hepadnaviridae family of viruses. The course of the virus is determined primarily by the age at which the infection is acquired and the interaction between the virus and the body's immune system. Successful treatment is associated with a reduction in liver injury and fibrosis (scarring), a decreased likelihood of developing cirrhosis and its complications, including liver cancer, and a prolonged survival.
Primary Sclerosing Cholangitis (PSC)
Primary sclerosing cholangitis or PSC is a disease of the liver. The cause of PSC is not known. Symptoms may include itching, fatigue, jaundice, fever, and confusion. The only treatment for Primary sclerosing cholangitis is a liver transplant.
Regular physical activity can reduce the risk of disease. Regular exercise can also reduce the symptoms of stress and anxiety. There are fitness programs that fit any age or lifestyle.
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Treatment & Diagnosis
- Creatinine Blood Test
- Complete Blood Count (CBC)
- MRI (Magnetic Resonance Imaging Scan)
- Photodynamic Therapy
- ERCP (Endoscopic Retrograde Cholangio-Pancreatography)
- CT Scan (Computerized Tomography)
- Radiation Therapy
- What Is a Biliary Endoscopic Sphincterotomy?
- Endoscopic Ultrasound
- What Is Balloon Endoscopy?
- What Is an Ampullectomy?
Medications & Supplements
- Dilaudid vs. Fentanyl (Pain Strength Comparison and Side Effects)
- hepatitis A and hepatitis B (recombinant) vaccine (Twinrix)
- hepatitis b vaccine (Recombivax HB)
- Pemazyre (pemigatinib)
- Ayvakit (avapritinib)
- Side Effects of Proleukin (aldesleukin)
- haemophilus b/hepatitis b vaccine - injection, Comvax
Prevention & Wellness
- Know the Signs of Rare But Deadly Gall Bladder, Bile Duct Cancers
- Pemazyre Approved for Treatment of Advanced Cholangiocarcinoma
- Type 2 Diabetes Tied to Raised Risk of Tumors, Cancer Deaths
- Chemo Drug May Buy Time for Those With Bile Duct Cancer
- Aspirin May Help Protect Against Bile Duct Cancer: Study
- One Woman's Cancer Battle Highlights Promise of New Treatment
- Researchers Spot Potential Bile Duct Cancer Drug Targets