What is Diprolene Lotion, and what is it used for?

Brand name: Diprolene

Generic: betamethasone dipropionate

Diprolene Lotion is a prescription topical corticosteroid used to treat the symptoms of plaque psoriasis and eczema. Diprolene Lotion may be used alone or with other medications. 

It is not known if Diprolene Lotion is safe and effective in children younger than 12 years of age.

What are the side effects of Diprolene Lotion?

What are the serious side effects of Diprolene Lotion?

Diprolene Lotion may cause serious side effects, including:

  • Diprolene Lotion can pass through your skin. Too much Diprolene Lotion passing through your skin can cause your adrenal glands to stop working properly. Your healthcare provider may do blood tests to check for adrenal gland problems.
  • Cushing's syndrome, a condition that happens when your body is exposed to too much of the hormone cortisol.
  • High blood sugar (hyperglycemia).
  • Effects on growth and weight in children.
  • Vision problems. Topical corticosteroids including Diprolene Lotion may increase your chance of developing cataract(s) and glaucoma. Tell your healthcare provider if you develop blurred vision or other vision problems during treatment with Diprolene Lotion.
  • Skin problems. Skin problems including, allergic reactions (contact dermatitis) may happen during treatment with Diprolene Lotion. Stop using Diprolene Lotion and tell your healthcare provider if you develop any skin reactions or have problems with healing during treatment with Diprolene Lotion.

What are the most common side effects of Diprolene Lotion?

The most common side effects of Diprolene Lotion include:

These are not all of the possible side effects of Diprolene Lotion.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Is Diprolene Lotion addictive?

No Information Provided

What is the dosage for Diprolene Lotion?

  • Apply a few drops of Diprolene Lotion to the affected skin areas once or twice daily and massage lightly until the lotion disappears.
  • Therapy should be discontinued when control is achieved. If no improvement is seen within 2 weeks, reassessment of diagnosis may be necessary. Diprolene Lotion is a super-high-potency topical corticosteroid. Treatment with Diprolene Lotion should be limited to 2 consecutive weeks and amounts should not exceed 50 mL per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis.
  • Diprolene Lotion should not be used with occlusive dressings unless directed by a physician.
  • Avoid use on the face, groin, or axillae, or if skin atrophy is present at the treatment site.
  • Avoid contact with eyes. Wash hands after each application.
  • Diprolene Lotion is for topical use only. It is not for oral, ophthalmic, or intravaginal use.

What drugs interact with Diprolene Lotion?

No Information Provided

QUESTION

Psoriasis causes the top layer of skin cells to become inflamed and grow too quickly and flake off. See Answer

Diprolene Lotion contraindications, and pregnancy and breastfeeding safety

Before using Diprolene Lotion, tell your healthcare provider about all of your medical conditions, including if you:

  • have had irritation or other skin reaction to a steroid medicine in the past.
  • have thinning of the skin (atrophy) at the treatment site.
  • have diabetes.
  • have adrenal gland problems.
  • have liver problems.
  • have cataracts or glaucoma.
  • are pregnant or plan to become pregnant. It is not known if Diprolene Lotion will harm your unborn baby. If you use Diprolene Lotion during pregnancy, use Diprolene Lotion on the smallest area of the skin and for the shortest time needed.
  • are breastfeeding or plan to breastfeed. It is not known if Diprolene Lotion passes into your breast milk. Breastfeeding women should use Diprolene Lotion on the smallest area of skin and for the shortest time needed while breastfeeding. Do not apply Diprolene Lotion directly to the nipple and areola to avoid contact with your baby.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Especially tell your healthcare provider if you take other corticosteroid medicines by mouth, or injection or use other products on your skin or scalp that contain corticosteroids.

Do not use other products containing a steroid medicine with Diprolene Lotion without talking to your healthcare provider first.

Summary

Diprolene Lotion is a prescription topical corticosteroid used to treat the symptoms of plaque psoriasis and eczema. Serious side effects of Diprolene Lotion include stopping adrenal glands from working, Cushing's syndrome, high blood sugar (hyperglycemia), effects on growth and weight in children, increasing your chance of cataract(s) and glaucoma, and allergic skin reactions.

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Medically Reviewed on 9/18/2021
References
All sections courtesy of the U.S. Food and Drug Administration