betamethasone dipropionate, Diprolene; Diprolene AF

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Psoriasis Symptoms, Causes and Treatment

What brand names are available for betamethasone dipropionate?

Diprolene, Diprolene AF, Luxiq

Is betamethasone dipropionate available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for betamethasone dipropionate?

Yes

What are the uses for betamethasone dipropionate?

Betamethasone is used for the relief of itching and inflammation associated with a wide variety of skin conditions in patients 13 years of age or older. Examples include allergic dermatitis, atopic dermatitis, contact dermatitis, and plaque psoriasis.

What are the side effects of betamethasone dipropionate?

The most common side effects of betamethasone are:

  • burning at the area of application,
  • itching,
  • irritation, and
  • dryness.

Quick GuidePsoriasis Types, Images, Treatments

Psoriasis Types, Images, Treatments

What is the dosage for betamethasone dipropionate?

  • A thin strip of betamethasone cream or ointment is applied gently to the affected area once or twice daily.
  • A few drops of the lotion is applied to the affected area once or twice daily.
  • The lotion should be massaged gently until it disappears.

Large doses and prolonged use of betamethasone may cause large amounts to be absorbed into the body and suppress production of cortisol by the adrenal glands. Therefore, the lotion should not be used for longer than two weeks, and not more than 50 ml should be used per week. The augmented cream or ointment should be limited to 45 grams per week. Betamethasone should not be used with occlusive dressings because occlusive dressings increase absorption into the body.

Which drugs or supplements interact with betamethasone dipropionate?

Combining topical steroids with topical anthralin may increase psoriasis symptoms. Therefore, topical steroids should be discontinued 1 week before starting anthralins.

Is betamethasone dipropionate safe to take if I'm pregnant or breastfeeding?

Use of betamethasone in pregnant women has not been studied. When corticosteroids are given systemically (orally, intramuscularly or intravenously) to pregnant animals fetal abnormalities occur.

It is not known if betamethasone is secreted in breast milk. Corticosteroids absorbed into the body may appear in breast milk and may cause harmful effects in breast fed infants.

What else should I know about betamethasone dipropionate?

What preparations of betamethasone dipropionate are available?

Cream, ointment, lotion: 0.05%

How should I keep betamethasone dipropionate stored?

All preparations should be kept at temperatures from 15 C to 30 C (59 F to 86 F). Lotion should be shaken before each use.

REFERENCE: AHFS Drug Information. Prescribing Information for Diprolene

Quick GuidePsoriasis Types, Images, Treatments

Psoriasis Types, Images, Treatments

Summary

Betamethasone dipropionate (Diprolene; Diprolene AF; [Diprosone and Alphatrex have been discontinued]) is a corticosteroid topical medication prescribed for relief of inflammation and itching associated with a variety of skin conditions for example:

Side effects, drug interactions, dosing information, and patient safety information should be reviewed prior to taking any medication.

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Reviewed on 9/15/2016
References
REFERENCE: AHFS Drug Information. Prescribing Information for Diprolene

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