Signs and symptoms of Bernard-Soulier disease include
- bleeding excessively from cuts and other injuries,
- nosebleeds (epistaxis),
- easy bruising,
- bleeding from the gums, and
- unusually heavy menstrual flow in women.
Newborns may show excessive bleeding after circumcision. There is frequently a history of another family member with similar bleeding symptoms. Severe bleeding following trauma can cause significant complications.
Cause of Bernard-Soulier disease
A defect in the platelet glycoprotein complex 1b-IX-V causes Bernard-Soulier disease, which people inherit in an autosomal recessive manner, meaning both parents must pass on a copy of the defective gene for a person to be affected.
Other bernard-soulier disease
- Bleeding Excessively from Cuts and Other Injuries
- Bleeding from the Gums
- Easy Bruising
- Nosebleeds (Epistaxis)
- Unusually Heavy Menstrual Flow in Women
Main Article on Bernard-Soulier Disease
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