Bernard-Soulier Disease (Giant Platelet Syndrome) Center

Bernard-Soulier disease is a rare inherited bleeding disorder caused by a defect in the platelet glycoprotein complex 1b-IX-V. Symptoms and signs include:

  • bruising,
  • nosebleeds,
  • gum bleeding, and
  • problems with anything that induces bleeding, such as
Treatment involves avoiding medications that interfere with clot formation, such as naproxen, ibuprofen, and aspirin. People with Bernard-Soulier syndrome should avoid contact sports. Read more: Bernard-Soulier Disease (Giant Platelet Syndrome) Article

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