benzonatate (Tessalon Perles)

• Benzonatate is a medication taken orally to suppress coughs. It has an anesthetic (numbing) action similar to that of benzocaine and numbs the stretch sensors in the lungs. It is the stretching of these sensors with breathing that causes the cough. Benzonatate begins to work within 15 to 20 minutes, and its effects last for approximately 3 to 8 hours. Benzonatate is unrelated to narcotics such as codeine which are frequently used to suppress coughs. (Another frequently used cough suppressant, dextromethorphan, which is found in many over-the-counter cough and cold preparations, is a derivative of the narcotics.)

Tessalon Perles

GENERIC AVAILABLE: Yes

Benzonatate is used for relieving cough.

The most frequent adverse reactions of benzonatate include:

• Sedation
• Headache
• Mild dizziness
• Constipation
• Nausea
• Vomiting

Other side effects that have been reported include:

• Nasal congestion
• Hallucinations
• Itching skin
• Rash
• Indigestion
• Confusion
• Numbness in the chest

Severe hypersensitivity reactions (including airway spasms and cardiovascular collapse) may occur from sucking or chewing the capsule instead of swallowing it.

Benzonatate should not be used in children who are less than 10 years of age because unintentional overdose and death have been reported in this age group.

• The usual dose of benzonatate is 100-200 mg three times daily as needed for cough.
• A maximum dose of 600 mg (3-6 capsules depending on the strength of the capsule) per day is recommended by the manufacturer.
• Capsules should be swallowed whole and they should not be sucked, broken, or chewed.

There are no known drug interactions with benzonatate.

• There is very little information about the effects on the fetus of benzonatate. Physicians may use it during pregnancy if its benefits are deemed to outweigh its potential but unknown risks.
• It is not known whether benzonatate is secreted into breast milk.

What preparations of benzonatate are available?

Capsules: 100, 150, and 200 mg.

How should I keep benzonatate stored?

Capsules should be stored at room temperature, between 15 C to 30 C (59 F to 86 F).