beclomethasone dipropionate inhaler/spray; Beconase AQ, QNASL

  • Pharmacy Author:
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    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

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What is beclomethasone (HFA)-oral aerosol inhaler, and how does it work (mechanism of action)?

Beclomethasone is a synthetic steroid of the glucocorticoid family. The naturally-occurring glucocorticoid that is produced by the adrenal gland is cortisol or hydrocortisone. Glucocorticoid steroids have potent anti-inflammatory actions. When used as a nasal inhaler or spray, the medication goes directly to the lining of the nose, and very little is absorbed into the body. The FDA approved beclomethasone nasal spray in September 1981.

What brand names are available for beclomethasone (HFA)-oral aerosol inhaler?

Beconase AQ, QNASL

Is beclomethasone (HFA)-oral aerosol inhaler available as a generic drug?

GENERIC AVAILABLE: No

Do I need a prescription for beclomethasone (HFA)-oral aerosol inhaler?

Yes

What are the side effects of beclomethasone (HFA)-oral aerosol inhaler?

The most common side effects associated with nasal beclomethasone are:

A bloody nasal discharge and septum perforation may occur.

Fungal infection of the nose and throat, slow wound healing, glaucoma, and cataracts are also associated with intranasal beclomethasone.

Higher doses of intranasal beclomethasone may result in more absorption into the body. This may decrease bone formation and increase bone breakdown (resorption), resulting in weak bones and a risk of fractures, especially in children.

High doses may suppress the adrenal glands and impair their ability to make natural glucocorticoid. People with such suppression (which can be identified by testing) need increased amounts of glucocorticoid orally or by the intravenous route during periods of high physical stress since higher amounts of glucocorticoids are needed by the body to fight physical stress.

Patients receiving beclomethasone may develop easy bruising if enough beclomethasone is absorbed into the body.

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What is the dosage for beclomethasone (HFA)-oral aerosol inhaler?

The usual dose for the inhalers is 1-2 sprays in each nostril twice daily (Beconase AQ) or 2 sprays in each nostril once daily (QNASL). Some patients may do well with lower doses, and some require higher doses.

Which drugs or supplements interact with beclomethasone (HFA)-oral aerosol inhaler?

No drug interactions have been described with nasal beclomethasone.

Is beclomethasone (HFA)-oral aerosol inhaler safe to take if I'm pregnant or breastfeeding?

There does not appear to be any increased risk of malformations in children born to mothers exposed to beclomethasone during pregnancy. Additionally, no dependency on the drug develops, and there are no withdrawal symptoms when the medication is stopped.

It is not known if beclomethasone is secreted in breast milk. Other medications in this class are secreted into breast milk. It is not known whether the small amounts that may appear in the milk are of any consequence to the infant.

What else should I know about beclomethasone (HFA)-oral aerosol inhaler?

What preparations of beclomethasone (HFA)-oral aerosol inhaler are available?

Nasal Inhaler: 42 or 80 mcg per spray

How should I keep beclomethasone (HFA)-oral aerosol inhaler stored?

Beclomethasone should be kept at room temperature, 15 C to 30 C (59 F to 86 F). It should be shaken well before each use.

Reference: FDA Prescribing Information

Quick GuideAsthma Symptoms, Causes, and Medications

Asthma Symptoms, Causes, and Medications

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Reviewed on 11/24/2014
References
Reference: FDA Prescribing Information

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