What is azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax)?
Azithromycin is a semi-synthetic macrolide antibiotic chemically related to erythromycin and clarithromycin (Biaxin). It is effective against a wide variety of bacteria such as Hemophilus influenzae, Streptococcus pneumoniae, Mycoplasma pneumoniae, Staphylococcus aureus, mycobacterium avium, and many others.
What brand names are available for azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax)?
Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax are the brand names available for azithromycin in the US.
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- What is azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax)?
- What brand names are available for azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax)?
- Is azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax) available as a generic drug?
- Do I need a prescription for azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax)?
- What are the uses for azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax)?
- What are the side effects of azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax)?
- What is the dosage for azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax)?
- Which drugs or supplements interact with azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax)?
- Is azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax) safe to use during pregnancy or while breastfeeding?
- What else should I know about azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax)?
Is azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax) available as a generic drug?
Do I need a prescription for azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax)?
What are the uses for azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax)?
Azithromycin is effective against susceptible bacteria causing:
- Otitis media (infection of the middle ear)
- Uncomplicated skin and skin structure infections
- Mycobacterium avium complex
- Acute bacterial flare ups of chronic obstructive pulmonary disease (COPD)
It also is effective for acute pelvic inflammatory disease and several sexually transmitted infectious diseases (STDs) such as nongonococcal urethritis and cervicitis.
What are the side effects of azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax)?
The most common side effects of azithromycin are:
Other possible side effects of azithromycin include:
Possible serious side effects of azithromycin include:
- Abnormal liver tests
- Cholestatic jaundice
- Steven-Johnson Syndrome
- Serious allergic reactions
- Abnormal heart beats
Antibiotics can alter the normal bacteria in the colon and encourage overgrowth of some bacteria such as Clostridium difficile, which causes inflammation of the colon (pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after starting azithromycin (diarrhea, fever, abdominal pain, and possibly shock) should contact their physician immediately.
What is the dosage for azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax)?
- Azithromycin (except Zmax) can be taken with or without food, but food reduces stomach upset.
- Zmax should be taken on an empty stomach 1 hour before or 2 hours after a meal since food reduces its absorption.
- The adult azithromycin dose is 500-2000 mg in multiple or single doses.
- For most infections, azithromycin is taken once daily for a relatively short course of treatment (usually five days).
- The first dose is often a "double dose," twice as much as the remainder of the doses given.
- For acute bacterial sinusitis, azithromycin way be taken once daily for three days.
- Zmax usually is given as a single 2 gm dose.
Which drugs or supplements interact with azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax)?
Infectious Disease Resources
Is azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax) safe to use during pregnancy or while breastfeeding?
What else should I know about azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax)?
What preparations of azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax) are available?
- Tablets: 250, 500, and 600 mg.
- Suspension: 100 mg/5 ml (teaspoon), 200 mg/5 ml (teaspoon).
- Powder for suspension (extended release): 2 g.
- Powder for oral suspension: 1 g.
- Powder for Injection: 500 mg. Z-PAK (Blister pack containing six 250 mg tablets); TRI-PAK (Blister pack containing three 500 mg tablets).
How should I keep azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax) stored?
- Tablets should be stored at room temperature between 15 C to 30 C (59 F to 86 F).
- Suspension and solution for injection should be kept between 5 C to 30C (41 F to 86 F).
How does azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax) work?
- Azithromycin, like all macrolide antibiotics, prevents bacteria from growing by interfering with their ability to make proteins. Because of the differences in the way proteins are made in bacteria and humans, the macrolide antibiotics do not interfere with production of proteins in humans. It is an unusual antibiotic in that it stays in the body for quite a while (has a long half-life), allowing for once-a-day dosing and for shorter treatment courses for most infections.
When was azithromycin (Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax) approved by the FDA?
- The FDA approved azithromycin in November 1991.
Azithromycin (Zithromax, Zithromax Z-Pak, Zithromax Tri-Pak, Zmax) is an antibiotic prescribed for the treatment of a wide variety of bacterial infections such as
- Otitis media (middle ear infection)
- Uncomplicated skin and skin structure infections
- Mycobacterium avium complex
- Acute bacterial flare ups of chronic obstructive pulmonary disease
- Acute pelvic inflammatory disease
- Several sexually transmitted infectious diseases such as nongonococcal urethritis and cervicitis
Side effects include:
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