- 10 Common Allergy Triggers Slideshow Pictures
- Take the Quiz on Allergies
- Nasal Allergy Relief Products Slideshow
- What is azelastine hydrochloride and fluticasone propionate, and how does it work (mechanism of action)?
- What are the side effects of azelastine hydrochloride and fluticasone propionate?
- What is the dosage for azelastine hydrochloride and fluticasone propionate?
- Which drugs or supplements interact with azelastine hydrochloride and fluticasone propionate?
- Is azelastine hydrochloride and fluticasone propionate safe to take if I'm pregnant or breastfeeding?
- What else should I know about azelastine hydrochloride and fluticasone propionate?
What is azelastine hydrochloride and fluticasone propionate, and how does it work (mechanism of action)?
Dymista is a prescription nasal spray used to treat symptoms of seasonal allergic rhinitis (inflammation of the lining of the nose) such as runny nose, stuffy nose, itching, and sneezing. Dymista contains two medicines, azelastine hydrochloride and fluticasone propionate, which are also available individually as nasal sprays. In Dymista, azelastine hydrochloride an antihistamine, and fluticasone propionate, a corticosteroid work in different yet complementary ways.
Azelastine hydrochloride blocks the release and actions of histamine, a chemical responsible for causing many of the symptoms of allergy. Fluticasone propionate is a corticosteroid that reduces inflammation and the body's immune response. When used together, azelastine hydrochloride and fluticasone propionate provide better relief of symptoms than either medicine alone. In clinical trials, Dymista was superior to azelastine nasal spray, fluticasone nasal spray, and placebo in providing symptom relief. Dymista was approved by the FDA in May, 2012.
What brand names are available for azelastine hydrochloride and fluticasone propionat?
Is azelastine hydrochloride and fluticasone propionate available as a generic drug?
Do I need a prescription for azelastine hydrochloride and fluticasone propionate?
What are the side effects of azelastine hydrochloride and fluticasone propionate?
The most common side effects of Dymista are changes in taste, nosebleeds, and headache.
Dymista may cause some more serious side effects including:
What is the dosage for azelastine hydrochloride and fluticasone propionate?
The recommended dose to treat seasonal allergic rhinitis is 1 spray in each nostril twice daily.
Which drugs or supplements interact with azelastine hydrochloride and fluticasone propionate?
Taking Dymista with alcohol or CNS depressants may cause additive drowsiness or sleepiness.
Fluticasone propionate is metabolized or broken down by the CYP3A4 enzymes in the liver. Strong inhibitors of CYP3A4 enzymes such as ritonavir (Norvir), ketoconazole (Extina, Nizoral), fluconazole (Diflucan), and itraconazole (Onmel, Sporanox) may increase its blood levels and increase the risk of side effects. Dymista should not be used with ritonavir or medicines containing ritonavir.
Is azelastine hydrochloride and fluticasone propionate safe to take if I'm pregnant or breastfeeding?
What else should I know about azelastine hydrochloride and fluticasone propionate?
What preparations of azelastine hydrochloride and fluticasone propionat are available?
Nasal spray: 137 mcg of azelastine hydrochloride and 50 mcg of fluticasone propionate (137 mcg/50 mcg) in each metered spray. Each canister delivers 120 metered sprays after priming.
How should I keep azelastine hydrochloride and fluticasone propionate stored?
Dymista nasal spray should be stored upright at room temperature, between 20 C to 25 C (68 F to 77 F).
Latest Allergies News
Azelastine hydrochloride and fluticasone propionate (Dymista) is a nasal spray that treats allergy-related nasal inflammation. Side effects, drug interactions, and use during pregnancy should be reviewed prior to taking any medication.
Multimedia: Slideshows, Images & Quizzes
Could I Be Allergic? Discover Your Allergy Triggers
Allergies are an overreaction of the immune system where the body's defenses react to substances such as pollen, food and more....
Home Allergy Quiz: Is Your Home Allergy-Proof?
Take this home allergy quiz and test your knowledge on allergens, dust mites, pollens and more to see how allergy-proof your home...
10 Worst Cities for Spring Allergies With Pictures
See pictures of the top 10 "spring allergy capitals", according to the Asthma and Allergy Foundation of America (AAFA). From...
Pictures of Allergy Relief Tips at Home: AC Filters, Electronic Air Cleaners, and More
Learn how a combination of medication, preventing allergens, and allergy relief products can reduce allergy symptoms and help you...
Nasal Irrigation: Natural Relief for Cold & Allergy Symptoms
Nasal irrigation can relieve sinus symptoms associated with colds & allergies. Learn how nasal irrigation can help unclog sinuses...
Out-of-Control Allergy Symptoms: Treatment Relief in Pictures
Learn 10 signs your allergies are out of control. See these surprising allergy symptoms and find out how to get relief for...
Nasal Allergy Attack: Causes, Triggers, Treatments
What causes allergies? What are your allergy triggers? Discover how allergies work, why our bodies react to them, whether...
Related Disease Conditions
An allergy refers to a misguided reaction by our immune system in response to bodily contact with certain foreign substances. ...
Cold, Flu, Allergy Treatments
Before treating a cold, the flu, or allergies with over-the-counter (OTC) medications, it's important to know what's causing the...
Allergy Treatment Begins At Home
Avoiding allergy triggers at home is one of the best ways to prevent allergy symptoms. Controlling temperature, humidity, and...
Treatment & Diagnosis
Medications & Supplements
- fexofenadine, Allegra, Allegra Allergy, Allegra Hives, Children's Allegra, Mucinex Allergy
- cetirizine, Zyrtec, Zyrtec Allergy, Zyrtec Hives
- loratadine and pseudoephedrine (Alavert Allergy & Sinus, Claritin-D, Claritin-D 24 hour)
- fluticasone (Flonase, Flonase Allergy Relief)
- Nasal Allergy Medications
Prevention & Wellness
- Allergy Season Springs Into Bloom
- Allergy Rates Surprisingly Similar Across the U.S., Study Finds
- Allergy 'Rescue' Shots May Work Better in Lower Thigh of Overweight Kids
- FDA Approves 'Dry' Nose Spray for Allergy
- Amish Farm Kids Have Lower Asthma, Allergy Risk: Study
- Allergy-Linked Mouth Breathing Spells Trouble for Kids
- Chlorine in Pools Raises Kids' Asthma, Allergy Risk
- Climate Change Could Sting Allergy, Asthma Sufferers
- 100 Worst Spring Allergy Cities
- 'Tis the Season For Allergy, Asthma
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
FDA Prescribing Information