- Take the Pancreatitis Quiz
- Boost Digestive Health
- Digestive Distress Slideshow: Problem Foods to Avoid
- What is attapulgite, and how does it work (mechanism of action)?
- Is attapulgite available as a generic drug?
- Do I need a prescription for attapulgite?
- What are the side effects of attapulgite?
- What is the dosage for attapulgite?
- Which drugs or supplements interact with attapulgite?
- Is attapulgite safe to take if I'm pregnant or breastfeeding?
- What else should I know about attapulgite?
What is attapulgite, and how does it work (mechanism of action)?
Attapulgite is an oral, nonabsorbed medication that is used in the management of diarrhea. It works by adsorbing (binding) large numbers of bacteria and toxins and reducing the loss of water. Attapulgite reduces the number of bowel movements, improves the consistency of loose or watery stools, and relieves the gastrointestinal cramping that often is associated with diarrhea.
What is the dosage for attapulgite?
Attapulgite is taken after each loose bowel movement.
- Adults and adolescents over the age of 12 years may take 1.2 to 1.5 grams per dose, up to 8.4 grams per day.
- Children 6 to 12 years of age may take 600 to 750 mg after each loose bowel movement and up to 4.5 grams per day.
- Children 3 to 6 years of age may take 300 mg after each loose bowel movement up to a total of 2.1 grams (7 doses) per day.
Which drugs or supplements interact with attapulgite?
Attapulgite can decrease the absorption of benztropine (Cogentin), trihexyphenidyl (Artane), loxapine (Loxitane) and dicyclomine (Bentyl) if taken at the same time. These medications should be taken at least 2 hours earlier or later than attapulgite. Attapulgite and other antidiarrheals can worsen constipation caused by opiate pain relievers such as oxycodone (Percocet), hydrocodone (Vicodin), propoxyphene (Darvon), morphine, and codeine.
Is attapulgite safe to take if I'm pregnant or breastfeeding?
Attapulgite is safe during pregnancy.
Attapulgite is safe to use in nursing mothers.
Attapulgite (Rheaban; Kaopectate Advanced Formula; Parepectolin; Diasorb; Diatrol; Donnagel) is a medication prescribed for the short-term treatment of diarrhea. Side effects, drug interactions, and pregnancy safety should be reviewed prior to using.
Related Disease Conditions
Intestinal Gas (Belching, Bloating, Flatulence)
Anal itching is the irritation of the skin at the exit of the rectum, known as the anus, accompanied by the desire to scratch....
Irritable Bowel Syndrome (IBS)
Irritable bowel syndrome (IBS) is a GI (gastrointestinal) disorder with signs and symptoms that include abdominal pain, bloating,...
Travelers should prepare for their trip by visiting their physician to get the proper vaccinations and obtain the necessary...
Diarrhea (Causes, Medicine, Remedies, Treatment)
Diarrhea is a change is the frequency and looseness of bowel movements. Symptoms associated with diarrhea are cramping, abdominal...
Travelers' diarrhea is generally contracted by eating contaminated food or drinking contaminated water. Food is the primary...
IBS-D (Irritable Bowel Syndrome with Diarrhea)
IBS-D or irritable bowel syndrome with diarrhea refers to IBS with diarrhea. Symptoms of IBS-D include intestinal gas...
Treatment & Diagnosis
- Drugs: The Most Common Medication Errors
- Medication Disposal
- Dangers of Mixing Medications
- How To Reduce Your Medication Costs
- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Drugs: Buying Prescription Drugs Online Safely
- Generic Drugs, Are They as Good as Brand-Names?
Medications & Supplements
Prevention & Wellness
Digestive Disorders Resources
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.