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- What is atenolol and chlorthalidone, and how does it work (mechanism of action)?
- What brand names are available for atenolol and chlorthalidone?
- Is atenolol and chlorthalidone available as a generic drug?
- Do I need a prescription for atenolol and chlorthalidone?
- What are the side effects of atenolol and chlorthalidone?
- What is the dosage for atenolol and chlorthalidone?
- Which drugs or supplements interact with atenolol and chlorthalidone?
- Is atenolol and chlorthalidone safe to take if I'm pregnant or breastfeeding?
- What else should I know about atenolol and chlorthalidone?
What is atenolol and chlorthalidone, and how does it work (mechanism of action)?
Atenolol/chlorthalidone is a combination of atenolol (Tenormin) and chlorthalidone (Hygroton) used for the treatment of high blood pressure. Atenolol is a beta-adrenergic blocking agent that blocks the effects of adrenergic drugs, for example, adrenaline or epinephrine, on nerves of the sympathetic nervous system. Atenolol reduces the heart rate and is useful in treating abnormally rapid heart rhythms. Atenolol also reduces the force of contraction of heart muscle and lowers blood pressure. Chlorthalidone is a diuretic (water pill). It works by reducing the kidneys' ability to hold on to salt and water and increasing the kidneys' production of urine (diuresis). It is used to eliminate excess salt and water from the body and to treat high blood pressure. The FDA approved atenolol/chlorthalidone in June 1984.
What are the side effects of atenolol and chlorthalidone?
Side effects of Atenolol/chlorthalidone are similar to side effects form the individual components and are:
What is the dosage for atenolol and chlorthalidone?
The recommended dose of atenolol/chlorthalidone is one tablet once daily starting with 50 mg/25 mg then increasing to 100 mg/25 mg if blood pressure control is not adequate.
Which drugs or supplements interact with atenolol and chlorthalidone?
- Chlorthalidone can lower blood potassium and magnesium levels because both potassium and magnesium are lost in the urine.
- Chlorthalidone reduces the kidney's ability to eliminate lithium (Lithobid) in the urine. As a result, patients taking chlorthalidone at the same time as drugs containing lithium may develop high levels of lithium and/or lithium toxicity.
- Atenolol can mask the early warning symptoms of low blood sugar (hypoglycemia), and should be used with caution in patients receiving treatment for diabetes. Combining atenolol with other drugs that reduce blood pressure or slow heart rate may lead to excessive blood pressure reduction or low heart rate.
Is atenolol and chlorthalidone safe to take if I'm pregnant or breastfeeding?
What else should I know about atenolol and chlorthalidone?
What preparations of atenolol and chlorthalidone are available?
Tablets: atenolol 50mg and chlorthalidone 25mg; atenolol 100mg and chlorthalidone 25mg.
How should I keep atenolol and chlorthalidone stored?
Tablets should be stored at room temperature, 15C and 30 C (59 F and 86 F).
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Related Disease Conditions
High Blood Pressure (Hypertension)
High blood pressure (hypertension) is a disease in which pressure within the arteries of the body is elevated. About 75 million people in the US have hypertension (1 in 3 adults), and only half of them are able to manage it. Many people do not know that they have high blood pressure because it often has no has no warning signs or symptoms. Systolic and diastolic are the two readings in which blood pressure is measured. The American College of Cardiology released new guidelines for high blood pressure in 2017. The guidelines now state that blood normal blood pressure is 120/80 mmHg. If either one of those numbers is higher, you have high blood pressure. The American Academy of Cardiology defines high blood pressure slightly differently. The AAC considers 130/80 mm Hg. or greater (either number) stage 1 hypertension. Stage 2 hypertension is considered 140/90 mm Hg. or greater. If you have high blood pressure you are at risk of developing life threatening diseases like stroke and heart attack.REFERENCE: CDC. High Blood Pressure. Updated: Nov 13, 2017.
High Blood Pressure Treatment (Natural Home Remedies, Diet, Medications)
High blood pressure (hypertension) means high pressure (tension) in the arteries. Treatment for high blood pressure include lifestyle modifications (alcohol, smoking, coffee, salt, diet, exercise), drugs and medications such as ACE inhibitors, angiotensin receptor blockers, beta blockers, diuretics, calcium channel blockers (CCBs), alpha blockers, clonidine, minoxidil, and Exforge.
Migraine headache is a type of headache associated with a sensitivity to light, smells, or sounds, eye pain, severe pounding on one side of the head, and sometimes nausea and vomiting. The exact cause of migraine headaches is not known. Triggers for migraine headaches include certain foods, stress, hormonal changes, strong stimuli (loud noises), and oversleeping. Treatment guidelines for migraines include medicine, pain management, diet changes, avoiding foods that trigger migraines, staying hydrated, getting adequate sleep, and exercising regularly. Prevention of migraine triggers include getting regular exercise, drinking water daily, reducing stress, and avoiding trigger foods.
Arrhythmias (Heart Rhythm Disorders)
Heart rhythm disorders vary from minor palpitations, premature atrial contractions (PACs), premature ventricular contractions (PVCs), sinus tachycardia, and sinus bradycardia, to abnormal heart rhythms such as tachycardia, ventricular fibrillation, ventricular flutter, atrial fibrillation, atrial flutter, paroxysmal supraventricular tachycardia (PSVT), Wolf-Parkinson-White syndrome, brachycardia, or heart blocks. Treatment is dependent upon the type of heart rhythm disorder.
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Reference: FDA Prescribing Information