Is Polyarteritis Nodosa Different from Lupus?

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

  • Medical Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Symptoms of Rheumatoid Arthritis

Ask the experts

I have been diagnosed with polyarteritis nodosa (PAN). How does PAN differ from lupus?

Doctor's response

Polyarteritis nodosa is a type of inflammation of the blood vessels (vasculitis) that affects medium- and large-sized arteries. Depending on which blood vessels are involved and specifically the tissues they supply, injury can occur to internal organs, such as the kidneys or bowel.

Systemic lupus erythematosus (SLE) is an autoimmune disease that can cause inflammation of many tissues of the body, including the skin, joints, lungs, heart, nervous system, and kidneys. SLE may or may not cause vasculitis.

Medically reviewed by John A. Daller, MD; American Board of Surgery with subspecialty certification in surgical critical care

REFERENCE:

"Clinical manifestations and diagnosis of polyarteritis nodosa in adults"
UpToDate.com


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Reviewed on 6/21/2017

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