Aseptic Necrosis: Symptoms & Signs

Medically Reviewed on 4/1/2020

Aseptic necrosis is a bone condition caused by poor blood supply to an area of bone, leading to localized bone death.

Aseptic necrosis begins as a painless bone abnormality and may not cause pain. Pain in the involved bone may develop over time, especially with use. For example, if a hip joint develops avascular necrosis in the ball of the hip joint, pain can be felt in the hip, buttocks, or groin, and limping may result.

Causes of aseptic necrosis

Trauma to the bone, damage to the blood vessels that supply oxygen to the bone, poor blood circulation to the bone, abnormally thick blood (hypercoagulable state), atherosclerosis, and inflammation of the blood vessel walls (vasculitis) can cause aseptic necrosis.

Other aseptic necrosis symptoms and signs

  • Pain in the Involved Bone With Use


8 First Aid Kit Essentials for Scrapes, Cuts, Bug Bites, and More See Slideshow

Subscribe to MedicineNet's Skin Care & Conditions Newsletter

By clicking "Submit," I agree to the MedicineNet Terms and Conditions and Privacy Policy. I also agree to receive emails from MedicineNet and I understand that I may opt out of MedicineNet subscriptions at any time.

Jameson, J. Larry, et al. Harrison's Principles of Internal Medicine, 20th Ed. New York: McGraw-Hill Education, 2018.