Canker sores or aphthous ulcers are one of the most common causes of painful sores in the mouth. The actual cause of canker sores is unknown; however, some triggers that may precipitate outbreaks in some people include stress, anxiety, oral trauma, hormonal changes, drugs, food allergies, toothpastes, and vitamin deficiencies. Read more: Are Canker Sores Contagious? Article
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