apixaban (Eliquis)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Atrial Fibrillation Facts

What brand names are available for apixaban?

Eliquis

Is apixaban available as a generic drug?

GENERIC AVAILABLE: No

Do I need a prescription for apixaban?

Yes

What are the uses for apixaban?

What are the side effects of apixaban?

The most common side effects of apixaban involves bleeding in the:

Bleeding due to apixaban may be fatal.

Major bleeding events were fewer in patients who received apixaban when compared to a similar group that received warfarin (Coumadin, Jantoven), another widely used drug for preventing blood clots.

Rash and serious allergic reactions also may occur.

Quick GuideAtrial Fibrillation: Heart Symptoms, Diagnosis, & Afib Treatment

Atrial Fibrillation: Heart Symptoms, Diagnosis, & Afib Treatment

What is the dosage for apixaban?

  • The usual dose in nonvalvular atrial fibrillation is 5 mg by mouth twice daily. For individuals 80 years or older, weighing less than or equal to 60 kg, or with reduced kidney function, the usual dose is 2.5 mg twice daily.
  • The recommended dose for treating DVT or pulmonary embolism is 10 mg twice daily for the first 7 days and then 5 mg twice daily. After six months of treatment, the dose may be reduced to 2.5 mg daily for prevention of DVT or pulmonary embolism.
  • When apixaban is used to prevent the risk of DVT after hip or knee replacement surgery, the suggested dose is 2.5 mg daily beginning 12 to 24 hours after the surgery is completed.

Is apixaban safe to take if I'm pregnant or breastfeeding?

  • There are no adequate studies in pregnant women. Use during pregnancy may increase the risk of bleeding during pregnancy and delivery. Apixaban should be avoided during pregnancy.
  • It is not known if apixaban is excreted in human milk. Nursing mothers should discontinue apixaban or discontinue nursing.

What else should I know about apixaban?

What preparations of apixaban are available?

Tablets: 2.5 and 5 mg

How should I keep apixaban stored?

Apixaban should be stored at room temperature, between 15 C and 30 C (59 F and 86 F).

Reference: FDA Prescribing Information

Quick GuideAtrial Fibrillation: Heart Symptoms, Diagnosis, & Afib Treatment

Atrial Fibrillation: Heart Symptoms, Diagnosis, & Afib Treatment

Summary

Apixaban (Eliquis) is a medication prescribed to prevent blood clots in the heart and and strokes in patients with

Side effects, drug interactions, patient safety, and warnings should be read prior to taking this medication.

Treatment & Diagnosis

Medications & Supplements

Prevention & Wellness

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See more info: apixaban on RxList
Reviewed on 9/19/2016
References
Reference: FDA Prescribing Information

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