Medical Definition of Anonychia

Reviewed on 6/30/2022

Anonychia is the absence of fingernails and toenails. This can occur at birth (congenital anonychia) as a result of a mutation in a gene known as RSPO4. Acquired anonychia can be related to frostbite, trauma, drug reactions, surgery, or circulatory disturbances.

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References
Jameson, J. Larry, et al. Harrison's Principles of Internal Medicine, 20th Ed. New York: McGraw-Hill Education, 2018.