GENERIC NAME: ANISTREPLASE - INJECTION (an-ISS-treh-plays)
BRAND NAME(S): Eminase
HOW TO USE: This medication is given by injection into a vein as soon as possible after heart attack symptoms occur. It will be given by a health care professional who will closely monitor your therapy.
SIDE EFFECTS: Bleeding and irregular heart rhythms may occur as a result of this drug. You will be monitored closely for signs of these effects. Notify your doctor of: itching, flushing, skin rash, fever, chills, headache, nausea, sweating, dizziness, muscle aches or tremor. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: This drug should not be used when the following conditions are present: bleeding, blood vessel abnormalities, brain tumor, history of stroke, recent surgery, extremely high blood pressure (200/120 or higher). This drug should be used with caution when the following conditions exist: childbirth within the last 10 days, blood clotting problems, endocarditis, recent retinal bleeding, recent gastrointestinal or urinary tract bleeding, ulcers, very high blood pressure (180/110), a recent invasive procedure, if you have ever had a synthetic graft placed (knitted Dacron), heart abnormalities. This medication should be used during pregnancy only if clearly needed. Discuss the risks and benefits with your doctor.
DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription drugs you may use, especially of: corticosteroids (e.g., prednisone), aspirin (or drugs related to aspirin), "blood thinners" (e.g., warfarin, heparin), aminocaproic acid, drugs used for high blood pressure, valproic acid, injectable cephalosporins, drugs used for arthritis (NSAID such as ibuprofen and naproxen), sulfinpyrazone. Do not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.
NOTES: Life style changes such as diet, not smoking and exercise are often recommended following a heart attack. It is important to understand what you can do to reduce your risk of a heart attack. Discuss this with your doctor or health care professional.
MISSED DOSE: Check with your doctor.
MEDICAL ALERT: Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).
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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.