GENERIC NAME: DEXTROAMPHETAMINE/AMPHETAMINE- ORAL (am-FET-a-meen/DEX-troe-am-FET-a-meen)
BRAND NAME(S): Adderall
WARNING: Misuse or abuse of amphetamine may cause serious (possibly fatal) heart and blood pressure problems. Amphetamine-type medications can be habit-forming. Use only as directed. If you use this drug for a long time, you may become dependent on it and may have withdrawal symptoms after stopping the drug. Consult your doctor or pharmacist for more details. (See also How to Use section).
USES: This combination medication is used to treat attention deficit hyperactivity disorder (ADHD) as part of a total treatment plan, including psychological, social, and other treatments. It may help to increase the ability to pay attention, concentrate, stay focused, and stop fidgeting.This product is a combination of stimulants (amphetamine and dextroamphetamine). It is thought to work by restoring the balance of certain natural substances (neurotransmitters) in the brain.This drug may also be used to treat a certain sleeping disorder (narcolepsy) to help you stay awake during the day. It should not be used to treat tiredness or to hold off sleep in people who do not have a sleep disorder.
HOW TO USE: Read the Medication Guide provided by your pharmacist before you start taking amphetamine/dextroamphetamine and each time you get a refill. If you have any questions, ask your doctor or pharmacist.Take this medication by mouth with or without food as directed by your doctor, usually 1 to 3 times a day. The first dose is usually taken when you wake up in the morning. If more doses are prescribed, take them as directed by your doctor, usually 4-6 hours apart. Taking this medication late in the day may cause trouble sleeping (insomnia).The dosage is based on your medical condition and response to treatment. Your doctor may adjust your dose to find the dose that is best for you. Follow your doctor's instructions carefully.Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.During treatment, your doctor may occasionally recommend stopping the medication for a short time to see whether there are any changes in your behavior and whether the medication is still needed.This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (including severe tiredness, sleep problems, mental/mood changes such as depression) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions immediately.Along with its benefits, this medication may rarely cause abnormal drug-seeking behavior (addiction). This risk may be increased if you have abused alcohol or drugs in the past. Take this medication exactly as prescribed to lessen the risk of addiction. Do not increase your dose or use this drug more often or for longer than prescribed. Properly stop this medication when so directed.When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.Tell your doctor if your condition does not improve or if it worsens.
SIDE EFFECTS: Loss of appetite, weight loss, dry mouth, stomach upset/pain, nausea/vomiting, dizziness, headache, diarrhea, fever, nervousness, and trouble sleeping may occur. If any of these effects persist or worsen, tell your doctor promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.This medication may raise your blood pressure. Check your blood pressure regularly and tell your doctor of any high results.Tell your doctor right away if you have any serious side effects, including: numbness/pain/skin color change/sensitivity to temperature in the fingers or toes, mental/mood/behavior changes (such as agitation, aggression, mood swings, depression, abnormal thoughts), uncontrolled movements, continuous chewing movements/teeth grinding, outbursts of words/sounds, change in sexual ability/desire, frequent/prolonged erections (in males).Get medical help right away if you have any very serious side effects, including: shortness of breath, chest/jaw/left arm pain, fainting, severe headache, fast/pounding/irregular heartbeat, seizures, swelling of the ankles/feet, extreme tiredness, blurred vision, weakness on one side of the body, slurred speech, confusion.A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
PRECAUTIONS: Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to sympathomimetic drugs (such as epinephrine, pseudoephedrine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood circulation problems (such as Raynaud's disease), certain mental/mood conditions (such as severe agitation, psychosis), personal/family history of mental/mood disorders (such as bipolar disorder, depression, psychotic disorder, suicidal thoughts), heart problems (including irregular heartbeat/rhythm, coronary artery disease, heart failure, cardiomyopathy, problems with the heart structure such as valve problems), family history of heart problems (such as sudden death/irregular heartbeat/rhythm), history of stroke, high blood pressure, overactive thyroid (hyperthyroidism), a certain eye problem (glaucoma), seizures, personal or family history of regular use/abuse of drugs/alcohol, personal or family history of uncontrolled muscle movements (such as Tourette's syndrome), kidney disease, liver disease.This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Children may be more sensitive to the side effects of this drug, especially weight loss. This medication may slow down a child's growth. The doctor may recommend temporarily stopping the medication from time to time to reduce this risk. Monitor your child's weight and height. Consult your doctor or pharmacist for more details.Older adults may be more sensitive to the side effects of this drug, especially chest pain, trouble sleeping, or weight loss.During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. Infants born to mothers who are dependent on this medication may be born too soon (premature) and have low birth weight. They may also have withdrawal symptoms. Tell your doctor immediately if you notice possible mood changes, agitation, or unusual tiredness in your newborn.This medication passes into breast milk and may have undesirable effects on a nursing infant. Therefore, breast-feeding is not recommended while using this drug. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Ask your doctor when to start or stop taking this medication.Check the labels on all your medicines (such as cough-and-cold products, diet aids) because they may contain ingredients that could increase your heart rate or blood pressure. Ask your pharmacist about using these products safely.Avoid drinking large amounts of beverages containing caffeine (coffee, tea, colas), eating large amounts of chocolate, or taking over-the-counter products that contain caffeine. Caffeine can increase the side effects of this medication.Dextroamphetamine is very similar to lisdexamfetamine. Do not use medications containing lisdexamfetamine while using dextroamphetamine.This medication may interfere with certain medical/laboratory tests (including blood and urine steroid levels, brain scan for Parkinson's disease), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.
OVERDOSE: If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe mental/mood changes, seizures, severe/persistent headache, severe restlessness, fast breathing.
NOTES: Do not share this medication with others. It is against the law.Laboratory and/or medical tests (such as blood pressure, heart rate, growth monitoring in children) may be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.
MISSED DOSE: If you miss a dose, take it as soon as you remember in the morning hours. If it is late in the afternoon or near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
STORAGE: Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Information last revised January 2014. Copyright(c) 2014 First Databank, Inc.
Latest MedicineNet News
Daily Health News
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Top amphetamine and dextroamphetamine Related Articles
13 Tips for Parenting a Teen With ADHDParenting a teenager who has attention deficit hyperactivity disorder (ADHD) can be challenging. Parents can use specific strategies to help their teen cope with school and homework. Special care should be taken to help an ADHD teen drive safely and avoid alcohol and drug use.
Adderall vs. Concerta
Amphetamine and dextroamphetamine (Adderall, Adderall XR) and Concerta (methylphenidate) are drugs prescribed for the treatment of ADHD (attention-deficit hyperactivity disorder) and narcolepsy. Side effects, drug interactions, warnings and precautions, and patient safety information should be reviewed prior to taking any medication.
Adderall vs. Ritalin (Differences and Similarities)
Adderall (dextroamphetamine, amphetamine) and Ritalin (methylphenidate) are drugs that stimulate the central nervous system or CNS, and are prescribed to treat ADHD in children and adults.
Common side effects of both drugs include:
- Stomach ache
- Vision problems
- Nausea or vomiting
- Increase in blood pressure
- Loss of appetite
- Weight loss
Side effects unique to Adderall include:
- Hair loss
- Difficulty having an orgasm
Side effects unique to Ritalin include:
- Numbness, tingling, or cold hands and feet
- Growth suppression
- Manic episodes
- Prolonged, painful erections (priapism)
- Peripheral vasculopathy
- Raynaud's phenomenon
Childhood ADD or ADHD (Attention Deficit Hyperactivity Disorder in Children)Attention deficit hyperactivity disorder (ADHD) causes the following symptoms in children: excessive activity, problems concentrating, and difficulty controlling impulses. There are three types of ADHD: the predominantly inattentive type, the predominantly hyperactive/impulsive type, and the combined (inattentive, hyperactive, and impulsive) type. Stimulant medications are the most common medication used to treat ADHD.
ADD or ADHD Medications
Attention deficity hyperactivity disorder (ADHD) affects 8%-10% of school-age children. ADHD medications are designed to increase the ability of the sufferer to pay attention and manage their impulses. ADHD drugs are available in liquid, pill, and patch form.
Childhood ADHD QuizFind out causes, symptoms, and treatments for Attention Deficit Hyperactivity Disorder, a widespread behavioral condition commonly seen in children. Take the Childhood ADHD Quiz.
Adult ADHD (Attention Deficit Hyperactivity Disorder)About 2%-6% of adults have ADHD, a common behavioral problem. Symptoms include impulsivity, hyperactivity, and inattention. Treatment may involve ADHD education, attending a support group, skills training, and medication.
Attention Deficit Hyperactivity Disorder (ADHD) in TeensAttention deficit hyperactivity disorder (ADHD) in teens is a disruption of neurocognitive functioning. Genetics contribute to ADHD. Symptoms of ADHD in teens include inattention, hyperactivity/impulsivity, or a combination of these. Treatment may include cognitive behavioral therapy, behavior therapy, medication, or alternative therapies.
Drug AbuseDrug addiction is a chronic disease that causes drug-seeking behavior and drug use despite negative consequences to the user and those around him. Though the initial decision to use drugs is voluntary, changes in the brain caused by repeated drug abuse can affect a person's self-control and ability to make the right decisions and increase the urge to take drugs. Drug abuse and addiction are preventable.
Drug Abuse SlideshowWhat is drug abuse? Learn about prescription drug abuse and over-the-counter (OTC) drugs, including depressants, pain relievers, and stimulants.
Drug interactions occur frequently. Get facts about the types of drug interactions, what substances or other things that may interact with drugs such as OTC drug and prescription drugs, vitamins, food(s) (grapefruit), and laboratory tests. Find out how to protect yourself from potential drug interactions.
Drugs: Questions to Ask Your Doctor or Pharmacist about Your DrugsImportant information about your drugs should be reviewed prior to taking any prescription drug. Side effects, drug interactions, warnings and precauctions, dosage, what the drug is used for, what to do if you miss a dose, how the drug is to be stored, and generic vs. brand names.
Encephalopathy means brain disease, damage, or malfunction. Causes of encephalopathy are varied and numerous. The main symptom of encephalopathy is an altered mental state. Other symptoms include:
- tremors, and
Treatment of encephalopathy depends on the type of encephalopathy (anoxia, diabetic, Hashimoto's, hepatic, hyper - hypotensive, infectious, metabolic, infections, uremic, or Wernicke's) are examples of types of encephalopathy.
MisophoniaMisophonia is defined as the hatred of sound. Symptoms of this condition include a negative emotional response to certain trigger sounds, such as slurping, snoring,yawning, orthroat clearing. Other symptoms include distancing oneself from the trigger, and acting out at the sound's source. Treatment may involve medications, cognitive behavioral therapy, or tinnitus retraining therapy.
Narcolepsy (Definition, Symptoms, Treatment, Medication)Causes of narcolepsy, a chronic disease of the central nervous system, have not been fully determined. Some theories include abnormalities in hypocretin neurons in the brain or an autoimmune disorder. Symptoms of narcolepsy include:
- excessive daytime sleepiness,
- hypnagogic hallucinations,
- sleep paralysis,
- disturbed nocturnal sleep, and
- automatic behavior.
Diagnosis of narcolepsy is based on a clinical evaluation, specific questionnaires, sleep logs or diaries, and the results of sleep laboratory tests. Treatments of narcolepsy symptoms include medication and lifestyle changes.
Stimulants (ADHD)Stimulants are compounds (caffeine, nicotine, cocaine) or medications that stimulate the CNS or central nervous system. Stimulants increase blood pressure, mental alertness, energy, and heart rate. Approved medical uses for stimulants include ADHD (attention deficit hyperactivity disorder) and transient resistant depression obesity. Stimulants can be highly addictive so they are no longer recommended for treating nervous system disorders and asthma. Drug interactions, dosage, and pregnancy and breastfeeding safety should be reviewed prior to taking this medication.
Vyvanse vs. AdderallVyvanse and Adderall are in the same class of drugs. Adderall is prescribed for the treatment of ADHD (attention-deficit hyperactivity disorder) and narcolepsy. Vyvanse is approved to treat ADHD and severe binge eating disorder. Side effects, drug interactions, warnings and precautions, and patient safety information should be reviewed prior to taking any medication.