- Bacterial Infections 101 Pictures Slideshow
- Take the Tummy Trouble Quiz
- Hepatitis C Slideshow Pictures
- Amoxicillin (amox-clav) vs. Augmentin comparison of differences
- What is amoxicillin? What is Augmentin? How do they work?
- What are the uses for amoxicillin vs. Augmentin?
- What are the side effects of amoxicillin vs. Augmentin?
- What is the dosage of amoxicillin vs. Augmentin?
- What drugs interactions occur with amoxicillin vs. Augmentin
- Are amoxicillin and Augmentin safe to take if I am pregnant or breastfeeding?
Amoxicillin (amox-clav) vs. Augmentin comparison of differences
- Amoxicillin and Augmentin (amoxicillin/clavulanate, amox-clav) are antibiotics used to treat bacterial infections including sinusitis, pneumonia, ear infections, bronchitis, urinary tract infections, and infections of the skin.
- Amoxicillin and Augmentin both belong to the penicillin drug class.
- A difference is that Augmentin is a combination medication that also contains clavulanic acid in addition to amoxicillin.
- Both amoxicillin and Augmentin are available as generic drugs.
- Side effects of amoxicillin and Augmentin that are similar include:
- Side effects of Augmentin that are different from amoxicillin include:
- Serious but rare reactions of amoxicillin and Augmentin include seizures, severe allergic reactions (anaphylaxis), and low platelet (thrombocytopenia) or red blood cell count.
- Amoxicillin rarely is associated with drug reactions or interactions. Augmentin may interact with probenecid, birth control pills, and allopurinol.
- Brand names amoxicillin include Amoxil, Moxatag, and Larotid.
What is amoxicillin? What is Augmentin? How do they work?
Amoxicillin belongs to a class of antibiotics called penicillins. Other members of this class include ampicillin (Unasyn), piperacillin (Pipracil), ticarcillin (Ticar), and several others. Amoxicillin is used to treat infections due to bacteria that are susceptible to the effects of amoxicillin. Common bacterial infections that amoxicillin is used for include infections of the middle ear, tonsils, throat, larynx (laryngitis), bronchi (bronchitis), lungs (pneumonia), urinary tract, and skin. Amoxicillin also is used to treat gonorrhea.
Augmentin (amoxicillin/clavulanate) is a combination antibiotic used to treat bacterial infections including sinusitis, pneumonia, ear infections, bronchitis, urinary tract infections, and infections of the skin. Amoxicillin belongs to the penicillin drug class.
What are the uses for amoxicillin vs. Augmentin?
- Amoxicillin is used to treat infections due to bacteria that are susceptible to the effects of amoxicillin.
- Common bacterial infections that amoxicillin is used for include infections of the
- It also is used to treat gonorrhea.
- Augmentin is effective against susceptible bacteria causing infections of the:
- middle ear (otitis media),
- throat infections (pharyngitis),
- sinusitis, and
- It also is used in treating urinary tract infections, and skin infections.
What are the side effects of amoxicillin vs. Augmentin?
Amoxicillin side effects
Common side effects of Amoxicillin include:
Other important side effects include:
- bloody or prolonged diarrhea,
- easy bruising or bleeding,
- reversible hepatitis,
- rash, and
- allergic reactions.
More serious side effects and adverse reactions include:
- severe allergic reactions (anaphylaxis), and
- low platelet or red blood cell count.
Augmentin side effects
Common side effects of Augmentin are:
- abdominal discomfort,
- nausea, and
- Other important side effects include:
- bloody or prolonged diarrhea,
- easy bruising or bleeding,
- reversible hepatitis,
- rash, and
- allergic reactions.
Serious but rare reactions include seizures, severe allergic reactions (anaphylaxis), and low platelet or red blood cell count.
Antibiotics like amoxicillin and Augmentin can alter the normal bacteria in the colon and encourage overgrowth of some bacteria such as Clostridium difficile which causes inflammation of the colon (pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after starting Augmentin (diarrhea, fever, abdominal pain, and possibly shock) should contact their physician immediately. Persons who are allergic to the cephalosporin class of antibiotics, which are related to the penicillins, for example, cefaclor (Ceclor), cephalexin (Keflex), and cefprozil (Cefzil), may or may not be allergic to penicillins.
What is the dosage of amoxicillin vs. Augmentin?
Amoxicillin dosage instructions
- For most infections in adults the dose of amoxicillin is 250 mg every 8 hours, 500 mg every 8 hours, 500 mg every 12 hours or 875 mg every 12 hours, depending on the type and severity of infection.
- For the treatment of adults with gonorrhea, the dose is 3 g given as one dose.
- For most infections, children older than 3 months but less than 40 kg are treated with 25 or 45 mg/kg/day in divided doses every 12 hours or 20 or 40 mg/kg/day with one-third of the daily dose given every 8 hours depending on the type and severity of the infection.
- Amoxicillin can be taken with or without food.
Augmentin dosage instructions
- Augmentin should be taken on a full stomach to reduce stomach upset. No more than one tablet should be taken at a time since the extra clavulanic acid can cause stomach upset.
- Recommended adult doses are 500 mg every 8-12 hours, 250 mg every 8 hours, 875 mg every 12 hours, or 2000 mg every 12 hours.
- Dosing is based on the amoxicillin component.
- Pediatric patients weighing more than 40 kg should receive adult doses.
- Pediatric patients weighing less than 40 kg should receive 20 to 45 mg/kg every 8 or 12 hours.
What drugs interactions occur with amoxicillin vs. Augmentin
Amoxicillin drug interactions
- Amoxicillin is rarely associated with important drug interactions.
Augmentin drug interactions
- Co-administration of probenecid, a drug used for treating gout, prevents the normal elimination of amoxicillin by the kidneys and can cause high, toxic blood levels of amoxicillin.
- Augmentin may decrease the effectiveness of birth control pills, increasing the risk of unexpected pregnancies.
- Combining Augmentin and allopurinol (Zyloprim, Aloprim) may increase the occurrence of skin rash.
Are amoxicillin and Augmentin safe to take if I am pregnant or breastfeeding?
- Penicillins are generally considered safe for use by pregnant women who are not allergic to penicillin.
- Small amounts of amoxicillin may be excreted in breast milk and may cause diarrhea or allergic responses in nursing infants. Amoxicillin is generally considered safe to use while breastfeeding. Amoxicillin is used to treat infections in the newborn.
- Use of Augmentin in pregnant women has not been well studied. Penicillins are generally considered safe for use by pregnant women who are not allergic to penicillin.
- Augmentin is excreted in breast milk and may cause diarrhea in the infant.
Latest Infectious Disease News
Daily Health News
Amoxicillin and Augmentin (amox-clav) are antibiotics used to treat a variety of bacterial infections that include bronchitis, tonsillitis, sinusitis, pneumonia, laryngitis, skin infections, and urinary tract infections. Amoxicillin is a penicillin antibiotic, and Augmentin or amox-clav chemically is closely related to ampicillin and penicillin.
Augmentin also causes side effects like gas, bloating, headache, and reversible hepatitis. Both amoxicillin and Augmentin have serious side effects that should be reviewed prior to taking either antibiotic.
Dosage instructions for amoxicillin and Augmentin depend upon the drug and type of bacterial infection being treated. Both antibiotics have drug interactions, and are not recommended if you are pregnant or breastfeeding.
Multimedia: Slideshows, Images & Quizzes
Sore Throat or Strep Throat? How to Tell the Difference
Is this a sore throat or could it be strep throat? Explore the causes of a sore throat, including strep throat, and learn how to...
Ear Infection Symptoms, Causes, and Treatment
Learn about the causes and symptoms of ear infections and how they are diagnosed and treated. Read about treatments such as ear...
Bacterial Infections 101: Types, Symptoms, and Treatments
Get more information on bacterial skin infections, which bacteria cause food poisoning, sexually transmitted bacteria, and more....
Urinary Tract Infection (UTI) Symptoms, Diagnosis, Medication
Bladder infections can be painful and often require medical treatment. Get the latest information on urinary tract infections...
Sinus Infection (Sinusitis) Symptoms & Treatment
Sinus infection (sinusitis) symptoms can include headaches, a sore throat, and toothaches. Antibiotics and home remedies can...
What Is a Staph Infection? Causes, Symptoms, Treatments
Do you know what a staph infection is? What about golden staph? Learn about the causes, symptoms, and treatments of staph...
What's Bronchitis? Symptoms and Treatments
Is bronchitis contagious? Learn about bronchitis, an inflammation of the lining of the lungs. Explore bronchitis symptoms,...
What happens within the body when a person develops bronchitis? Take this quick quiz to learn the causes, symptoms, treatments,...
Ear Infection Quiz: Test Your Medical IQ
Is it possible to prevent ear infections? Take the Ear Infection (Otitis Media) Quiz to learn the risks, causes, symptoms and...
Strep (Streptococcal) Throat Infection Quiz: Test Your Infectious Disease IQ
Take the Strep (Streptococcal) Throat Infection Quiz to learn about causes, symptoms, treatments, prevention methods, diagnosis,...
Urinary Tract Infection Quiz
How would you know if you had urinary tract infection (UTI)? Take the Urinary Tract Infection in Adult Quiz to learn the causes,...
Picture of The Clap (Gonorrhea)
A sexually transmitted infection (STI) caused by the bacterium Neisseria gonorrhoea. See a picture of The Clap (Gonorrhea) and...
Related Disease Conditions
Sinus Infection (Sinusitis)
Sinus infection (sinusitis) is caused by allergies, infection, and chemicals or other irritants of sinuses. Signs and symptoms include headache, fever, and facial tenderness, pressure, or pain. Treatments of sinus infections are generally with antibiotics and at times, home remedies.
Cellulitis is an acute spreading bacterial infection below the surface of the skin characterized by redness, warmth, inflammation, and pain. The most common cause of cellulitis is the bacteria staph (Staphylococcus aureus).
Urinary Tract Infection (UTI)
A urinary tract infection (UTI) is an infection of the bladder, kidneys, ureters, or urethra. E. coli, a type of bacteria that lives in the bowel and near the anus, causes most UTIs. UTI symptoms include pain, abdominal pain, mild fever, urinary urgency, and frequency. Treatment involves a course of antibiotics.
Staph (Staphylococcus) Infection
Staphylococcus or staph is a group of bacteria that can cause a multitude of diseases. Staph infections can cause illness directly by infection or indirectly by the toxins they produce. Symptoms and signs of a staph infection include redness, swelling, pain, and drainage of pus. Minor skin infections are treated with an antibiotic ointment, while more serious infections are treated with intravenous antibiotics.
Middle Ear Infection (Otitis Media)
A middle ear infection (otitis media) can cause earache, temporary hearing loss, and pus drainage from the ear. It is most common in babies, toddlers, and young children. Learn about causes and treatment.
Gonorrhea In Women
Gonorrhea is a bacterial infection transmitted during sexual contact. In women, symptoms include a yellow vaginal discharge, burning or frequent urination, and redness, swelling, burning, and itching of the vaginal area. Gonorrhea can be treated with injectable (penicillin) or oral medications.
Impetigo is a contagious skin infection caused by staph and strep bacteria. There are two types of impetigo: nonbullous and bullous. Symptoms of nonbullous impetigo include small blisters on the nose, face, arms, or legs and possibly swollen glands. Bullous impetigo signs include blisters in various areas, particularly in the buttocks area. Treatment involves gentle cleansing, removing the crusts of popped blisters, and the application of prescription-strength mupirocin antibiotic ointment.
Is Strep Throat Contagious?
Strep throat is caused by group A streptococcus bacteria. Incubation period for strep throat is 1-5 days after exposure. If strep throat is treated with antibiotics, it is no longer contagious after 24 hours; if it is not treated with antibiotics, it is contagious for 2-3 weeks. Symptoms include fever, sore throat, tonsillitis, white spots or patches on the tonsils, and nausea and vomiting. Diagnosis of strep throat is performed through a rapid strep test.
Strep throat is a bacterial infection of the throat. Signs and symptoms of strep throat include headache, nausea, vomiting, sore throat, and fever. Strep throat symptoms in infants and children are different than in adults. Strep throat is contagious and is generally passed from person to person. Treatment for strep throat symptoms includes home remedies and OTC medication; however, the only cure for strep throat are antibiotics.
Is a Staph Infection Contagious?
A staph infection is caused by the bacteria Staphylococcus aureus. Staph can cause boils, food poisoning, cellulitis, toxic shock syndrome, MRSA, and various other illnesses and infections. Most staph infections are transmitted from person to person.
Bronchitis is inflammation of the airways in the lung. Acute bronchitis is short in duration (10-20 days) in comparison with chronic bronchitis, which lasts for months to years. Causes of acute bronchitis include viruses and bacteria, which means it can be contagious. Acute bronchitis caused by environmental factors such as pollution or cigarette smoke is not contagious. Common symptoms for acute bronchitis include nasal congestion, cough, headache, sore throat, muscle aches, and fatigue. Acute bronchitis in children also my include runny nose, fever, and chest pain. Treatment for acute bronchitis are OTC pain relievers, cough suppressants (although not recommended in children), and rest. Infrequently antibiotics may be prescribed to treat acute bronchitis.
SIBO (Small Intestinal Bacterial Overgrowth)
Small intestinal bacterial overgrowth (SIBO) refers to a condition in which abnormally large numbers of bacteria (at least 100,000 bacteria per ml of fluid) are present in the small intestine, but they are more like the bacteria that are found in the colon. There are many conditions associated with SIBO, including: Diabetes Scleroderma Crohn's disease Irritable bowel syndrome (IBS) It has been theorized that SIBO may be responsible for the symptoms of at least some patients with irritable bowel syndrome. Symptoms of SIBO include: Excess gas Abdominal bloating Abdominal pain Treatment for SIBO can include: Antibiotics Probiotics Low FODMAP Diet
Is a Urinary Tract Infection (UTI) Contagious?
Bacteria such as E. coli or Pseudomonas can cause a urinary tract infection (UTI). The incubation period for a UTI ranges from three to eight days.
Is a Sinus Infection Contagious?
Sinus infection (sinusitis) is infection (viral, bacterial, or fungal) or inflammation of the sinuses. Symptoms of sinus infection are cough, bad breath, coughing up greenish-yellow sputum, sinus headache, and other symptoms of the common cold. Treatments of sinus infection are home remedies to soothe symptoms and antibiotics if the infection is bacterial or fungal.
Chronic bronchitis is a cough that occurs daily with production of sputum that lasts for at least 3 months, 2 years in a row. Causes of chronic bronchitis include cigarette smoking, inhaled irritants, and underlying disease processes (such as asthma, or congestive heart failure). Symptoms include cough, shortness of breath, and wheezing. Treatments include bronchodilators and steroids. Complications of chronic bronchitis include COPD and emphysema.
Neck Pain and Dizziness
Neck pain is any degree of discomfort in the front or back of the neck between the head and the shoulders. Dizziness is characterized as either vertigo with disequilibrium or lightheadedness associated with feeling faint or the potential to lose consciousness. Causes of neck pain and dizziness vary, and treatment depends on the cause. With any unexplained or persisting neck pain or dizziness, consult with a health care professional, who can determine whether the symptoms are harmless and temporary or serious and threatening.
Group A streptococcal infections are caused by group A Streptococcus, a bacteria that causes a variety of health problems, including strep throat, impetigo, cellulitis, erysipelas, and scarlet fever. There are more than 10 million group A strep infections each year.
Urinary Tract Infections in Children
Urinary tract infections (UTIs) are very common in children. Symptoms and signs include fever and abdominal pain. Associated symptoms and signs include flank pain, vomiting, and blood in the urine. Treatment for a UTI involves antibiotic therapy.
Is Impetigo Contagious?
Impetigo is a contagious bacterial infection that usually occurs in children ages 2-5. There are two types of impetigo: bullous and nonbullous. With nonbullous impetigo, pus-filled blisters develop, ooze, and crust over on the patient's torso, in contrast with bullous impetigo, which is typically confined to the extremities and the face near the mouth.
Melioidosis (Whitmore's disease) is an infectious disease caused by Burkholderia pseudomallei bacteria. Symptoms include bronchitis, pneumonia, fever, headache, loss of appetite, cough, and chest pain. Treatment involves antibiotics or surgical removal of the lung abscess in severe cases.
Emphysema, Chronic Bronchitis, and Colds
If you have a COPD such as emphysema, avoiding chronic bronchitis and colds is important to avoid a more severe respiratory infection such as pneumonia. Avoiding cigarette smoking, practice good hygeine, stay away from crowds, and alerting your healthcare provider if you have a sinus infection or cold or cough that becomes worse. Treatment options depend upon the severity of the emphysema, bronchitis, or cold combination.
Treatment & Diagnosis
Medications & Supplements
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.