- Bacterial Infections 101 Pictures Slideshow
- Take the Tummy Trouble Quiz
- Hepatitis C Slideshow Pictures
Amoxicillin vs. Cipro
- Amoxicillin and Cipro (ciprofloxacin) are antibiotics used to treat bacterial infections of the skin, lungs or airways, urinary tract, and to treat gonorrhea.
- Amoxicillin is also used to treat bacterial infections of the middle ear, tonsils, and throat.
- Cipro is also used to treat bacterial infections of the bones and joints. Cipro is also used to treat infectious diarrheas caused by E. coli, Campylobacter jejuni, and Shigella bacteria; anthrax patients with fever and low white blood cell counts, and intra-abdominal infections; typhoid fever; chronic bacterial prostatitis; and acute uncomplicated cystitis
- Brand names of amoxicillin include Moxatag and Amoxil.
- Amoxicillin and Cipro belong to different antibiotic drug classes. Amoxicillin is a penicillin-type antibiotic and Cipro is a fluoroquinolone antibiotic.
- Side effects of amoxicillin and Cipro that are similar include diarrhea, abdominal pain, nausea, vomiting, and rash.
- Side effects of amoxicillin that are different from Cipro include dizziness, heartburn, sleep problems (insomnia), itching, confusion, easy bruising, bleeding, and allergic reactions.
- Side effects of Cipro that are different from amoxicillin include headache and restlessness. Cipro and Cipro XR and other fluoroquinolone antibiotics have been associated with tendonitis and even tendon rupture, particularly the Achilles tendon.
What is Amoxicillin? What is Cipro?
Amoxicillin is a penicillin-type antibiotic, in the same class as ampicillin (Unasyn), piperacillin (Pipracil), and ticarcillin (Ticar). These antibiotics stop bacteria from multiplying by preventing bacteria from forming the walls that surround them. The walls are needed to protect bacteria from their environment and to hold the contents of a bacterial cell together. Bacteria cannot survive without a cell wall. Amoxicillin is effective against a number of different bacteria such as H. influenzae, Streptococci, Pneumococci, N. gonorrhoea, E. coli, and certain strains of Staphylococci. Amoxicillin is used to treat bacterial infections of the tonsils, throat, middle ear, larynx (laryngitis), lungs (pneumonia), bronchi (bronchitis), urinary tract, and skin. Amoxicillin also is used to treat gonorrhea.
Cipro (ciprofloxacin) is a fluoroquinolone antibiotic used to treat bacterial infections of the skin, lungs or airways, bones, joints, and urinary tract. Cipro is also used to treat infectious diarrheas caused by E. coli, Campylobacter jejuni, and Shigella bacteria; anthrax patients with fever and low white blood cell counts, and intra-abdominal infections; typhoid fever; cervical and urethral gonorrhea due to Neisseria gonorrhoeae; chronic bacterial prostatitis; and acute uncomplicated cystitis. Cipro works by stopping the multiplication of bacteria by inhibiting the reproduction and repair of their genetic material (DNA). Other fluoroquinolones include levofloxacin (Levaquin), ofloxacin (Floxin), gatifloxacin (Tequin), norfloxacin (Noroxin), moxifloxacin (Avelox), and trovafloxacin (Trovan).
What are side effects for amoxicillin and Cipro?
Side effects due to amoxicillin include
- abdominal pain,
- easy bruising,
- rash, and
- allergic reactions.
People who are allergic to the cephalosporin class of antibiotics, which are related to the penicillins, for example, cefaclor (Ceclor), cephalexin (Keflex), and cefprozil (Cefzil), may or may not be allergic to penicillins.
Serious but rare reactions include:
- severe allergic reactions (anaphylaxis), and
- low platelet (thrombocytopenia) or red blood cell count.
Amoxicillin can alter the normal bacteria in the colon and encourage overgrowth of some bacteria such as Clostridium difficile which causes inflammation of the colon (pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after starting amoxicillin (diarrhea, fever, abdominal pain, and possibly shock) should contact their physician immediately.
Cipro and Cipro XR as well as other antibiotics in the fluoroquinolone class of antibiotics has been associated with tendonitis and even tendon rupture, particularly the Achilles tendon. Some doctors and other medical professionals recommend that their patients discontinue vigorous exercise while they are taking fluoroquinolone antibiotics.
The most common side effects of Cipro, Cipro XR are:
Anaphylaxis, or shock, is a rare allergic reaction to this drug. This allergic reaction is a medical emergency and you are experiencing these symptoms seek medical immediately.
Symptoms of shock include:
What are the serious side effects and adverse events of Cirpo?
Possible serious side effects of Cipro, Cipro XR include:
- Peripheral neuropathy
- Central nervous system effects (CNS), for example, toxic psychosis, nervousness, agitation, insomnia, anxiety, nightmares, paranoia, dizziness, tremors, depression, and hallucinations.
- Clostridiumdifficile-associated diarrhea (CDAD)
- Abnormal heart beats
- Liver dysfunction
- Toxic epidermal necrolysis
- Stevens-Johnson syndrome
- Allergic pneumonitis
- Interstitial nephritis
- Acute kidney failure
- Liver failure
Other serious side effects and adverse events of Cipro, Cipro XR include:
- Cipro, Cipro XR should be used with caution in patients with central nervous system diseases such as seizures, because rare seizures have been reported in patients receiving Cipro, Cipro XR.
- Cipro, Cipro XR should be avoided in children and adolescents less than 18 years of age, as safe use in these patients has not been established.
- Many antibiotics, including Cipro, Cipro XR, can alter the normal bacteria in the colon and encourage overgrowth of a bacterium responsible for the development of inflammation of the colon, (C. difficile or pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after starting Cipro, Cipro XR (diarrhea, fever, abdominal pain, and possibly shock) should contact their doctor immediately.
- Cardiac arrest
- Respiratory failure
Latest Infectious Disease News
Daily Health News
What is the dosage of amoxicillin vs. Cipro?
- For most infections in adults the dose of amoxicillin is 250 mg every 8 hours, 500 mg every 8 hours, 500 mg every 12 hours or 875 mg every 12 hours, depending on the type and severity of infection.
- For the treatment of adults with gonorrhea, the dose is 3 g given as one dose.
- For most infections, children older than 3 months but less than 40 kg are treated with 25 or 45 mg/kg/day in divided doses every 12 hours or 20 or 40 mg/kg/day with one-third of the daily dose given every 8 hours depending on the type and severity of the infection.
- Amoxicillin can be taken with or without food.
- For most infections the recommended oral dose for adults is 250-750 mg (immediate release tablets) every 12 hours or 500-1000 mg (extended release tablets) every 24 hours.
- The usual intravenous dose is 200-400 mg every 8-12 hours.
What drugs interact with amoxicillin vs. Cipro?
Amoxicillin is rarely associated with important drug interactions.
- Ciprofloxacin administered together with theophylline (Respbid, Slo-Bid, Theo-24, Theolair) can lead to elevated, toxic blood levels of theophylline. Theophylline is used to open airways in the treatment of asthma. Toxic levels of theophylline can lead to seizures, and disturbances in heart rhythm. If concurrent use of ciprofloxacin and theophylline cannot be avoided, frequent blood tests to monitor theophylline blood levels are recommended.
- Ciprofloxacin increases the effect of tizanidine (Zanaflex) that is used to treat muscle spasticity. Therefore, the two drugs should not be combined.
- Iron salts (for example, ferrous sulfate) may reduce the absorption of ciprofloxacin because of formation of a ciprofloxacin-iron complex that is not absorbable. Antacids also may reduce the absorption of ciprofloxacin. If patients are receiving iron salts or antacids and ciprofloxacin, the ciprofloxacin should be given two hours before or six hours after the iron salt or antacid.
- Ciprofloxacin may increase the blood thinning effect of warfarin (Coumadin, Jantoven). The reason for this is unknown. Anticoagulant activity should be monitored after starting or stopping ciprofloxacin.
- Sevelamer (Renagel) may reduce the absorption of ciprofloxacin and possibly reduce the effectiveness of ciprofloxacin. Milk and orange juice also may reduce the absorption of ciprofloxacin. Ciprofloxacin, as with iron and antacids, should be given two hours before or six hours after milk or orange juice.
- Administration of ciprofloxacin with diabetic medications (for example glyburide [Micronase, Diabeta, Glynase, Prestab]) may lead to severe low blood glucose.
- Ciprofloxacin may increase blood concentrations of sildenafil (Viagra) that is used for treating erectile dysfunction. This combination should be avoided if possible.
- Patients taking Cipro, Cipro XR can develop sensitivity of the skin to direct sunlight (photosensitivity) and should avoid exposure to sunlight or use sunblock.
- Fluoroquinolones worsen low blood glucose levels when combined with sulfonylureas, for example, glyburide (Micronase, Diabeta, Glynase, Prestab).
Are amoxicillin and Cipro safe to use while pregnant or breastfeeding?
- Penicillins are generally considered safe for use by pregnant women who are not allergic to penicillin.
- Small amounts of amoxicillin may be excreted in breast milk and may cause diarrhea or allergic responses in nursing infants. Amoxicillin is generally considered safe to use while breastfeeding. Amoxicillin is used to treat infections in the newborn.
Doctors suggest that should not use this antibiotic if you are pregnant or breastfeeding because they do not know if it is safe.
Subscribe to MedicineNet's General Health Newsletter
Amoxicillin (Amoxil) and Cipro (ciprofloxacin) are antibiotics used to treat bacterial infections of the skin, lungs or airways, urinary tract, and to treat gonorrhea. Amoxicillin is also used to treat bacterial infections of the middle ear, tonsils, and throat. Cipro is also used to treat bacterial infections of the bones and joints. Cipro is also used to treat infectious diarrheas caused by E. coli, Campylobacter jejuni, and Shigella bacteria; anthrax patients with fever and low white blood cell counts, and intra-abdominal infections; typhoid fever; chronic bacterial prostatitis; and acute uncomplicated cystitis
Multimedia: Slideshows, Images & Quizzes
Recognize These Common Eye Problems
Eye diseases can cause damage and blindness if not treated soon enough. Learn the warning signs and symptoms of common eye...
Bacterial Infections 101: Types, Symptoms, and Treatments
Get more information on bacterial skin infections, which bacteria cause food poisoning, sexually transmitted bacteria, and more....
Ear Infection Symptoms, Causes, and Treatment
Learn about the causes and symptoms of ear infections and how they are diagnosed and treated. Read about treatments such as ear...
Respiratory Illnesses: 13 Types of Lung Infections
Is your cough caused by a cold, flu, pneumonia or something else? Learn causes of respiratory infection like bronchitis,...
Bladder Infections: UTI Causes, Symptoms, Treatments
Urinary tract infections (UTI), including bladder infections, affect women and men, causing UTI symptoms like kidney infection....
Ear Infection Quiz: Test Your Medical IQ
Is it possible to prevent ear infections? Take the Ear Infection (Otitis Media) Quiz to learn the risks, causes, symptoms and...
Related Disease Conditions
Inner Ear Infection (Symptoms, Signs, Treatments, Home Remedies)
An inner ear infection or otitis interna is caused by viruses or bacteria and can occur in both adults and children. An inner ear infection can cause symptoms and signs, for example, a severe ear, dizziness, vertigo, nausea and vomiting, and vertigo. An inner ear infection also may cause inflammation of the inner ear or labyrinthitis. Inner ear infections are not contagious; however, the bacteria and viruses that cause the infection can be transmitted to other people. Good hygiene practices will help decrease the chances of the infection spreading to others. Inner ear infection symptoms and signs like ear pain and nausea may be relieved with home remedies or over the counter (OTC) medication. Some inner ear infections will need to be treated and cured with antibiotics or prescription pain or antinausea medication.
Staph (Staphylococcus) Infection
Staphylococcus or staph is a group of bacteria that can cause a multitude of diseases. Staph infections can cause illness directly by infection or indirectly by the toxins they produce. Symptoms and signs of a staph infection include redness, swelling, pain, and drainage of pus. Minor skin infections are treated with an antibiotic ointment, while more serious infections are treated with intravenous antibiotics.
Upper Respiratory Infection (URTI)
An upper respiratory infection is a contagious infection of the structures of the upper respiratory tract, which includes the sinuses, nasal passages, pharynx, and larynx. Common causes of an upper respiratory infection include bacteria and viruses such as rhinoviruses, group A streptococci, influenza, respiratory syncytial, whooping cough, diphtheria, and Epstein-Barr. Examples of symptoms of upper respiratory infection include sneezing, sore throat, cough, fever, and nasal congestion. Treatment of upper respiratory infections are based upon the cause. Generally, viral infections are treated symptomatically with over-the-counter (OTC) medication and home remedies.
Ear Infection Home Treatment
Infections of the outer, middle, and inner ear usually are caused by viruses. Most outer (swimmer's ear) and middle ear (otitis media) infections can be treated at home with remedies like warm compresses for ear pain relief, tea tree, ginger, or garlic oil drops. Symptoms of an outer ear (swimmer's ear) and middle ear infection include mild to severe ear pain, pus draining from the ear, swelling and redness in the ear, and hearing problems. Middle and inner ear infections may cause fever, and balance problems. Inner ear infections also may cause nausea, vomiting, vertigo, ringing in the ear, and labyrinthitis (inflammation of the inner ear). Most outer and middle ear infections do not need antibiotics. Inner ear infections should be treated by a doctor specializing in ear and hearing problems.
Middle Ear Infection (Otitis Media)
Middle ear infection (otitis media) is inflammation of the middle ear. There are two forms of this type of ear infection, acute and chronic. Acute otitis media is generally short in duration, and chronic otitis media generally lasts several weeks. Babies, toddlers, and children with a middle ear infection may be irritable, pull and tug at their ears, and experience numerous other symptoms and signs. Treatment depends upon the type of ear infection.
H. pylori (Helicobacter Pylori) Infection
Helicobacter pylori (H. pylori) is a bacteria that causes chronic inflammation (gastritis) of the inner lining of the stomach, and also is the most common cause of ulcers worldwide. About 50% of people in the world carries or is infected with H. pylori. Common symptoms of H. pylori infection are occasional abdominal discomfort, bloating, belching or burping, and nausea and vomiting. H. pylori infection is difficult to eradicate, and treatment is with two or more antibiotics.
Amebiasis (Entamoeba Histolytica Infection)
Amebiasis is an infection caused by an amoeba. Signs and symptoms include bloody stools, abdominal pain, weight loss, fever, and gas. Treatment may involve taking luminal agents or antibiotics. Surgery may be indicated for various reasons.
Urinary Tract Infection (UTI)
A urinary tract infection (UTI) is an infection of the bladder, kidneys, ureters, or urethra. E. coli, a type of bacteria that lives in the bowel and near the anus, causes most UTIs. UTI symptoms include pain, abdominal pain, mild fever, urinary urgency and frequency. Treatment involves a course of antibiotics.
Bladder Infection (Cystitis)
Bladder infection is an infection of the bladder, usually caused by bacteria or, rarely, by Candida. Certain people, including females, the elderly, men with enlarged prostates, and those with chronic medical conditions are at increased risk for bladder infection. Bladder infections are treated with antibiotics, but cranberry products and adequate hydration may help prevent bladder infections.
MRSA (methicillin-resistant Staphylococcus aureus) bacteria causes skin infections with the following signs and symptoms: cellulitis, abscesses, carbuncles, impetigo, styes, and boils. Normal skin tissue doesn't usually allow MRSA infection to develop. Individuals with depressed immune systems and people with cuts, abrasions, or chronic skin disease are more susceptible to MRSA infection.
Is a Staph Infection Contagious?
A staph infection is caused by the bacteria Staphylococcus aureus. Staph can cause boils, food poisoning, cellulitis, toxic shock syndrome, MRSA, and various other illnesses and infections. Most staph infections are transmitted from person to person.
Is a Urinary Tract Infection (UTI) Contagious?
Bacteria such as E. coli or Pseudomonas can cause a urinary tract infection (UTI). The incubation period for a UTI ranges from three to eight days.
Is a Sinus Infection Contagious?
Sinus infection (sinusitis) is infection (viral, bacterial, or fungal) or inflammation of the sinuses. Symptoms of sinus infection are cough, bad breath, coughing up greenish-yellow sputum, sinus headache, and other symptoms of the common cold. Treatments of sinus infection are home remedies to soothe symptoms and antibiotics if the infection is bacterial or fungal.
Group A streptococcal infections are caused by group A Streptococcus, a bacteria that causes a variety of health problems, including strep throat, impetigo, cellulitis, erysipelas, and scarlet fever. There are more than 10 million group A strep infections each year.
Urinary Tract Infections in Children
Urinary tract infections (UTIs) are very common in children. Symptoms and signs include fever and abdominal pain. Associated symptoms and signs include flank pain, vomiting, and blood in the urine. Treatment for a UTI involves antibiotic therapy.
Urinary Tract Infection in Adults
Second Source article from Government
Second Source article from Government
Group A Streptococcal Infections
Second Source article from Government
CRE Bacteria Infection
Carbapenem-resistant Enterobacteriaceae (CRE) is a type of bacteria that is highly resistant to antibiotics. Escherichia coli (E. coli) and Klebsiella are common types of Enterobacteriaceae that can be found in the human intestines. However, these bacteria can cause infections if they escape the intestines. Carbapenems are broad-spectrum antibiotics that treat infections caused by bacteria that are highly resistant to other types of antibiotics.
Cyclospora Infection (Cyclosporiasis)
Cyclospora cayetanensis is a parasite that causes infection when humans ingest food contaminated with feces from an infected individual. Symptoms include profuse diarrhea, abdominal pain, gas, cramping, and fatigue. A 7-day course of Bactrim or Septra is the standard treatment for cyclosporiasis.
Treatment & Diagnosis
- Ear Infection FAQs
- Kidney Infections During Pregnancy
- Is It Easier to Get Staph Infection When You've Had it Before?
- How Do You Get Staph Infection?
- What Causes an Ear Infection?
- How Do You Get an Ear Infection?
- How to Get Rid of a Staph Infection
- E. coli Infection Facts
- Air Travel, Colds, and Sinus Infections
Medications & Supplements
Prevention & Wellness
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.