Medical Definition of Ambiguous genitalia

Reviewed on 3/29/2021

Ambiguous genitalia: Genitalia that are neither typically female nor typically male. Also known as intersexual genitalia.

Girls (with a 46, XX chromosome constitution) can have virilized genitalia due to excess androgen action. Conversely, the genitalia in boys (with a 46, XY chromosome constitution) can appear undermasculinized or frankly feminized because of lack of androgen action.

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