What is Amaryl (glimepiride)?
- Amaryl (glimepiride) is an oral diabetes medication used in addition to diet and exercise to control blood sugar in adults with type 2 diabetes.
- Management of blood sugar with Amaryl can help decrease the risk of eye, kidney, and nerve damage.
- Amaryl is not used for treating type 1 diabetes.
Common side effects of Amaryl include:
Serious side effects of Amaryl include:
- anemia,
- low blood platelets,
- low sodium,
- sensitivity to sunlight,
- liver dysfunction,
- serious allergic reactions,
- and low blood sugar (hypoglycemia)
- symptoms of low blood sugar include:
- hunger,
- nausea,
- tiredness,
- sweating,
- headache,
- heart palpitations,
- numbness around the mouth,
- tingling in the fingers,
- tremors,
- muscle weakness,
- blurred vision,
- chilliness,
- excessive yawning,
- irritability,
- confusion,
- and loss of consciousness
- symptoms of low blood sugar include:
Drug interactions of Amaryl include medications that, when given in combination with Amaryl may reduce its ability to lower blood sugar, including:
- diuretics,
- corticosteroids,
- phenytoin,
- colesevelam,
- danazol,
- somatropin,
- and rifampin.
Beta-blockers can cause low or high blood sugar.
The following, when given in combination with Amaryl, may increase the risk of low blood sugar (hypoglycemia):
- Nonsteroidal anti-inflammatory drugs (NSAIDs),
- sulfa drugs,
- warfarin,
- miconazole,
- fluconazole,
- chloramphenicol,
- cimetidine,
- ranitidine,
- clarithromycin,
- monoamine oxidase inhibitors (MAOIs),
- probenecid,
- quinolone antibiotics,
- and selective serotonin reuptake inhibitors (SSRIs).
Combining Amaryl with insulin may increase risk of heart-related side effects.
In animal studies, Amaryl and other sulfonylureas were associated with a higher risk of fetal death. However, there have been no good studies in women.
Abnormal blood sugar concentrations (high or low) during pregnancy increase the risk of abnormalities in the fetus. Physicians must carefully weigh the benefits and risks of Amaryl treatment during pregnancy. Insulin is the drug of choice for treating diabetes in pregnant women.
It is unknown if Amaryl is excreted in breast milk like other sulfonylureas. Because of the risk of low blood sugar in the infant, it is recommended that Amaryl be discontinued while breastfeeding. If therapy other than diet and exercise is needed, insulin is preferred.
What are the important side effects of Amaryl (glimepiride)?
Common side effects of glimepiride include:
A rash and allergic reactions also may occur. Flu-like symptoms have also been reported with glimepiride therapy.
Possible serious side effects of glimepiride include:
- Anemia
- Low blood platelets
- Low sodium
- Sensitivity to sunlight
- Liver dysfunction
- Serious allergic reactions
Low blood sugar (hypoglycemia) can occur during glimepiride therapy. Symptoms of low blood sugar include:
- Hunger
- Nausea
- Tiredness
- Perspiration
- Headache
- Heart palpitations
- Numbness around the mouth
- Tingling in the fingers
- Tremors
- Muscle weakness
- Blurred vision
- Chilliness
- Excessive yawning
- Irritability
- Confusion
- Loss of consciousness
Glimepiride is a derivative of a sulfonamide drug. People allergic to other sulfonamide-related drugs may develop an allergic reaction to glimepiride. Anyone who has an allergic reaction to sulfa drugs should not take glimepiride.
Amaryl (glimepiride) side effects list for healthcare professionals
The following serious adverse reactions are discussed in more detail below and elsewhere in the labeling:
- Hypoglycemia
- Hemolytic anemia
In clinical trials, the most common adverse reactions with Amaryl were hypoglycemia, dizziness, asthenia, headache, and nausea.
Clinical Trials Experience
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.
Approximately 2,800 patients with type 2 diabetes have been treated with Amaryl in the controlled clinical trials. In these trials, approximately 1,700 patients were treated with Amaryl for at least 1 year.
Table 1 summarizes adverse events, other than hypoglycemia, that were reported in 11 pooled placebocontrolled trials, whether or not considered to be possibly or probably related to study medication. Treatment duration ranged from 13 weeks to 12 months.
Terms that are reported represent those that occurred at an incidence of ≥ 5% among Amaryl-treated patients and more commonly than in patients who received placebo.
Table 1: Eleven Pooled Placebo-Controlled Trials ranging from 13 weeks to 12 months : Adverse Events (Excluding Hypoglycemia) Occurring in ≥ 5% of Amaryl-treated Patients and at a Greater Incidence than with Placebo*
Amaryl N=745 % | Placebo N=294 % | |
Headache | 8.2 | 7.8 |
Accidental Injury† | 5.8 | 3.4 |
Flu Syndrome | 5.4 | 4.4 |
Nausea | 5.0 | 3.4 |
Dizziness | 5.0 | 2.4 |
*Amaryl doses ranged from 1-16 mg administered daily †Insufficient information to determine whether any of the accidental injury events were associated with hypoglycemia |
Hypoglycemia
- In a randomized, double-blind, placebo-controlled monotherapy trial of 14 weeks duration, patients already on sulfonylurea therapy underwent a 3-week washout period then were randomized to Amaryl 1 mg, 4 mg, 8 mg or placebo.
- Patients randomized to Amaryl 4 mg or 8 mg underwent forced-titration from an initial dose of 1 mg to these final doses, as tolerated.
- The overall incidence of possible hypoglycemia (defined by the presence of at least one symptom that the investigator believed might be related to hypoglycemia; a concurrent glucose measurement was not required) was 4% for Amaryl 1 mg, 17% for Amaryl 4 mg, 16% for Amaryl 8 mg and 0% for placebo. All of these events were self-treated.
- In a randomized, double-blind, placebo-controlled monotherapy trial of 22 weeks duration, patients received a starting dose of either 1 mg Amaryl or placebo daily.
- The dose of Amaryl was titrated to a target fasting plasma glucose of 90-150 mg/dL. Final daily doses of Amaryl were 1, 2, 3, 4, 6 or 8 mg.
- The overall incidence of possible hypoglycemia (as defined above for the 14-week trial) for Amaryl vs. placebo was 19.7% vs. 3.2%.
- All of these events were self-treated.
Weight gain: Amaryl, like all sulfonylureas, can cause weight gain.
Allergic Reactions: In clinical trials, allergic reactions, such as pruritus, erythema, urticaria, and morbilliform or maculopapular eruptions, occurred in less than 1% of Amaryl-treated patients. These may resolve despite continued treatment with Amaryl. There are postmarketing reports of more serious allergic reactions (e.g., dyspnea, hypotension, shock).
Laboratory Tests
Elevated Serum Alanine Aminotransferase (ALT): In 11 pooled placebo-controlled trials of Amaryl, 1.9% of Amaryl-treated patients and 0.8% of placebo-treated patients developed serum ALT greater than 2 times the upper limit of the reference range.
Postmarketing Experience
The following adverse reactions have been identified during post-approval use of Amaryl. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
- Serious hypersensitivity reactions, including anaphylaxis, angioedema, and Stevens-Johnson Syndrome
- Hemolytic anemia in patients with and without G6PD deficiency
- Impairment of liver function (e.g. with cholestasis and jaundice), as well as hepatitis, which may progress to liver failure.
- Porphyria cutanea tarda, photosensitivity reactions and allergic vasculitis
- Leukopenia, agranulocytosis, aplastic anemia, and pancytopenia
- Thrombocytopenia (including severe cases with platelet count less than 10,000/μL) and thrombocytopenic purpura
- Hepatic porphyria reactions and disulfiram-like reactions
- Hyponatremia and syndrome of inappropriate antidiuretic hormone secretion (SIADH), most often in patients who are on other medications or who have medical conditions known to cause hyponatremia or increase release of antidiuretic hormone
- Dysgeusia
- Alopecia
What drugs interact with Amaryl (glimepiride)?
Drugs Affecting Glucose Metabolism
A number of medications affect glucose metabolism and may require Amaryl dose adjustment and particularly close monitoring for hypoglycemia or worsening glycemic control.
The following are examples of medications that may increase the glucose-lowering effect of sulfonylureas including Amaryl, increasing the susceptibility to and/or intensity of hypoglycemia:
- oral anti-diabetic medications,
- pramlintide acetate,
- insulin,
- angiotensin converting enzyme (ACE) inhibitors,
- H2 receptor antagonists,
- fibrates,
- propoxyphene,
- pentoxifylline,
- somatostatin analogs,
- anabolic steroids and androgens,
- cyclophosphamide,
- phenyramidol,
- guanethidine,
- fluconazole,
- sulfinpyrazone,
- tetracyclines,
- clarithromycin,
- disopyramide,
- quinolones,
- and those drugs that are highly protein-bound, such as:
- fluoxetine,
- nonsteroidal anti-inflammatory drugs,
- salicylates,
- sulfonamides,
- chloramphenicol,
- coumarins,
- probenecid
- and monoamine oxidase inhibitors.
When these medications are administered to a patient receiving Amaryl, monitor the patient closely for hypoglycemia. When these medications are withdrawn from a patient receiving Amaryl, monitor the patient closely for worsening glycemic control.
The following are examples of medications that may reduce the glucose-lowering effect of sulfonylureas including Amaryl, leading to worsening glycemic control:
- danazol,
- glucagon,
- somatropin,
- protease inhibitors,
- atypical antipsychotic medications (e.g., olanzapine and clozapine),
- barbiturates,
- diazoxide,
- laxatives,
- rifampin,
- thiazides
- and others:
- diuretics,
- corticosteroids,
- phenothiazines,
- thyroid hormones,
- estrogens,
- oral contraceptives,
- phenytoin,
- nicotinic acid,
- sympathomimetics (e.g., epinephrine, albuterol, terbutaline),
- and isoniazid.
When these medications are administered to a patient receiving Amaryl, monitor the patient closely for worsening glycemic control. When these medications are withdrawn from a patient receiving Amaryl, monitor the patient closely for hypoglycemia.
Beta-blockers, clonidine, and reserpine may lead to either potentiation or weakening of Amaryl's glucose-lowering effect.
Both acute and chronic alcohol intake may potentiate or weaken the glucose-lowering action of Amaryl in an unpredictable fashion.
The signs of hypoglycemia may be reduced or absent in patients taking sympatholytic drugs such as:
- beta-blockers,
- clonidine,
- guanethidine,
- and reserpine.
Miconazole
A potential interaction between oral miconazole and sulfonylureas leading to severe hypoglycemia has been reported. Whether this interaction also occurs with other dosage forms of miconazole is not known.
Cytochrome P450 2C9 Interactions
- There may be an interaction between glimepiride and inhibitors (e.g., fluconazole) and inducers (e.g., rifampin) of cytochrome P450 2C9.
- Fluconazole may inhibit the metabolism of glimepiride, causing increased plasma concentrations of glimepiride which may lead to hypoglycemia.
- Rifampin may induce the metabolism of glimepiride, causing decreased plasma concentrations of glimepiride which may lead to worsening glycemic control.
Concomitant Administration Of Colesevelam
- Colesevelam can reduce the maximum plasma concentration and total exposure of glimepiride when the two are coadministered.
- However, absorption is not reduced when glimepiride is administered 4 hours prior to colesevelam.
- Therefore, Amaryl should be administered at least 4 hours prior to colesevelam.
Summary
Amaryl (glimepiride) is an oral diabetes medication used in addition to diet and exercise to control blood sugar in adults with type 2 diabetes. Management of blood sugar with Amaryl can help decrease the risk of eye, kidney, and nerve damage. Amaryl is not used for treating type 1 diabetes. Common side effects of Amaryl include dizziness, headache, nausea, vomiting, rash, allergic reactions, and flu-like symptoms. In animal studies, Amaryl and other sulfonylureas were associated with a higher risk of fetal death. Because of the risk of low blood sugar in the infant, it is recommended that Amaryl be discontinued while breastfeeding.
Multimedia: Slideshows, Images & Quizzes
-
Type 2 Diabetes: Signs, Symptoms, Treatments
Learn about type 2 diabetes warning signs, symptoms, diagnosis, and treatment options. Find out why thirst, headaches, and...
-
Diabetes: What Raises and Lowers Your Blood Sugar Level?
Want to lower your blood sugar? Learn to better control your glucose levels by preventing blood sugar spikes and swings to avoid...
-
Diabetes Nerve Pain: Improving Diabetic Peripheral Neuropathy
Learn how to cope with the symptoms of diabetic peripheral neuropathy through pain management exercises. Find relief for diabetic...
-
Type 1 Diabetes (T1D): Symptoms, Causes, Treatments, Vs. Type 2
What is type 1 diabetes? There are new treatments for juvenile diabetes, and more people with diabetes can be treated than ever...
-
Diabetes: How Blood Sugar Levels Affect Your Body
High blood sugar can be a sign of diabetes or prediabetes. The drugs that treat it sometimes cause low blood sugar too. WebMD...
-
Foot Health: Reasons You Feel Burning in Your Feet
The feeling of burning in your feet isn't just an annoyance. It might also be a sign of a more serious condition. Find out more...
-
Diabetes Tips: Managing and Living With Diabetes
If you have either type 1 or type 2 diabetes, you need to approach life differently. Learn nutrition tips to control blood sugar,...
-
How Diabetes Can Affect Your Feet
Learn more about diabetes related foot problems. For people with diabetes, too much glucose in the blood can cause serious foot...
-
Prediabetes: You Can Turn It Around
Prediabetes can be a wake-up call. Click through to find out what you can do if you have it.
-
Diabetes: 12 Ways Too Much Sugar Harms Your Body
The bitter truth: How too much sugar can harm your physical and mental health.
-
Diabetes Diet: Healthy Meal Plans for Diabetes-Friendly Eating
Discover the best and worst meals for diabetes-savvy dining. See how to avoid carbs and control your blood sugar with healthier...
-
Type 2 Diabetes: Test Your Medical IQ
What causes type 2 diabetes? Can it be prevented? Take this online quiz and challenge your knowledge of this common condition....
-
Type 1 Diabetes Quiz: Test Your Medical IQ
What are the causes of type 1 diabetes? Take this quiz and challenge your knowledge of causes, symptoms, diagnosis and treatments...
-
Diabetes Quiz: Test Your Medical IQ
Take the Diabetes Quiz and learn the causes, signs, symptoms, and types of this growing epidemic. What does diabetes have to do...
-
Diabetes Travel: Tips for Better Diabetes Control
Diabetes shouldn't stop you from traveling! Learn tips for packing diabetic supplies, controlling blood sugar while changing time...
-
Diabetes Diet: 11 Low-Sugar Drink Ideas
Searching for low-sugar drink ideas? This pictures slideshow has eleven beverages ideal for people with diabetes and those...
-
Diabetes: 15 Famous Celebrities With Diabetes
See pictures of celebrities that have been diagnosed with type 1 or type 2 diabetes including Mary Tyler Moore, Salma Hayek, and...
-
Slideshow: Diabetes Management in 10 Minutes
Learn 10 simple ways to better manage your diabetes. See tips for controlling blood sugar, diet and exercise and other helpful...
-
Diabetes: Guide to Diabetic Peripheral Neuropathy
Diabetes can damage the nerves that help you feel pain, heat, and cold, especially in your feet. Learn about the symptoms of...
-
10 Muscle-Building Exercises for Diabetes
Watch this slideshow on Diabetes and Exercise. If you have diabetes, see how strengthening your muscles with these 10 weight...
-
Diabetes: Diabetic Peripheral Neuropathy Treatment
This nerve damage is a common complication of both type 1 and type 2 diabetes. Find out how to prevent it, slow its progression,...
Related Disease Conditions
-
Normal Blood Sugar Levels In Adults with Diabetes
People with diabetes can manage and prevent low or high blood sugar levels (hyperglycemia or hypoglycemia) by keeping a log of your blood sugar levels when you are eating and fasting and eat foods that are high in carbohydrates and sugar, for example, buttered potatoes, candy, sugary desserts, and fatty foods. Blood tests, for example, the hemoglobin A1c test (A1c test) and urinalysis can diagnose the type of diabetes the person has. Diabetes during pregnancy, called gestational diabetes, should be managed by you and your OB/GYN or another healthcare professional. Extremely high levels of blood glucose in the blood can be dangerous and life threatening if you have type 1, type 2, or gestational diabetes. If you or someone that you are with has extremely high blood glucose levels, call 911 or go to your nearest Urgent Care or Emergency Department immediately. To prevent and manage high blood glucose levels in people with diabetes keep a log of your blood sugar levels, eat foods that are high in carbohydrates sugar, for example, buttered potatoes, candy, sugary deserts, and fatty foods that you can share with your doctor and other healthcare professionals.
-
Diabetes (Type 1 and Type 2)
Diabetes is a chronic condition characterized by high levels of sugar (glucose) in the blood. The two types of diabetes are referred to as type 1 (insulin dependent) and type 2 (non-insulin dependent). Symptoms of diabetes include increased urine output, thirst, hunger, and fatigue. Treatment of diabetes depends on the type.
-
Type 2 Diabetes Diet Plan
A type 2 diabetes diet or a type 2 diabetic diet is important for blood sugar (glucose) control in people with diabetes to prevent complications of diabetes. There are a variety of type 2 diabetes diet eating plans such as the Mediterranean diet, Paleo diet, ADA Diabetes Diet, and vegetarian diets.Learn about low and high glycemic index foods, what foods to eat, and what foods to avoid if you have type 2 diabetes.
-
Pregnancy and Gestational Diabetes
Gestational diabetes is a form of diabetes that can occur during pregnancy. Pregnant women with gestational diabetes have not had the condition prior to becoming pregnant. Usually, gestational diabetes has no symptoms or signs and of gestational diabetes. Gestational diabetes can cause insulin resistance, hypoglycemia, hypoglycemia, and diabetic ketoacidosis. Treatment of gestational diabetes is managing the condition by checking your blood sugar as recommended, diet changes, getting enough exercise, and monitoring your baby's growth.
-
Diabetes-Related Dental Problems
Second Source WebMD Medical Reference
-
Type 2 Diabetes: Diagnosing Diabetes
Second Source WebMD Medical Reference
-
Controlling Diabetes
Second Source WebMD Medical Reference
-
Diabetes Symptoms in Women
Diabetes symptoms in women include vaginal itching, pain, or discharge, loss of interest or pain after having sex, polycystic ovarian syndrome (POS), and urinary tract infections or UTIs (which are more common in women. Symptoms of diabetes that are the same in women and men are excessive thirst and hunger, bad breath, and skin infections, darkening of skin in areas of body creases (acanthosis nigricans), breath odor that is fruity, sweet, or acetone, and tingling or numbness in the hands or feet, blurred vision, fatigue, tingling or numbness in the hands or feet, wounds that heal slowly, irritability, and weight loss or gain. Complications of type 1 and type 2 diabetes are the same, for example, skin, eye, and circulation problems, low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), ketoacidosis, and amputation. If diabetes is not managed a person may not survive.
-
Type 2 Diabetes
Type 2 diabetes is a chronic condition that may be reversible with diet and lifestyle changes. Symptoms include excessive thirst, frequent urination, weight loss, fatigue, and an unusual odor to your urine. Most people don't know they have type 2 diabetes until they have a routine blood test. Treatment options include medications, a type 2 diabetes diet, and other lifestyle changes.
-
Diabetes Treatment: Medication, Diet, and Insulin
The major goal in treating diabetes is controlling elevated blood sugar without causing abnormally low levels of blood sugar. Type 1 diabetes is treated with: insulin, exercise, and a diabetic diet. Type 2 diabetes is first treated with: weight reduction, a diabetic diet, and exercise. When these measures fail to control the elevated blood sugar, oral medications are used. If oral medications are still insufficient, insulin medications are considered.
-
Diabetes Symptoms in Men
Early symptoms of diabetes are different in men, such as low testosterone. In many cases, prediabetes that will progress to type 2 diabetes if it is not treated early.
-
Prediabetes
Prediabetes is a situation where a person's blood sugar levels are higher than they should be, but aren't high enough to be diagnosed with type 2 diabetes. There are no signs or symptoms of prediabetes. Some of the risk factors for prediabetes are high blood pressure, high cholesterol, heart disease, smoking, family history, poor diet, and lack of activity. Diet changes along with other healthy lifestyle changes are important in treating prediabetes.
-
Type 1 vs. Type 2 Diabetes: Differences
Diabetes mellitus is a metabolic condition in which a person's blood sugar (glucose) levels are too high. Over 29.1 million children and adults in the US have diabetes. Of that, 8.1 million people have diabetes and don't even know it. Type 1 diabetes (insulin-dependent, juvenile) is caused by a problem with insulin production by the pancreas. Type 2 diabetes (non-insulin dependent) is caused by: Eating a lot of foods and drinking beverages with simple carbohydrates (pizza, white breads, pastas, cereals, pastries, etc.) and simple sugars (donuts, candy, etc.) Consuming too many products with artificial sweeteners (We found out that they are bad for us!) Lack of activity Exercise Stress Genetics While the signs and symptoms of both types of diabetes are the same, which include: Increased urination Increased hunger Increased thirst Unexplained weight loss. However, the treatments are different. Type 1 diabetes is insulin dependent, which means a person with this type of diabetes requires treatment with insulin. People with type 2 diabetes require medication, lifestyle changes like eating a healthy diet, and getting regular exercise.
-
Diabetes and Safe Medications for Colds & Flu
If you have diabetes and catch a cold or the flu, can be more difficult to recover from infections and their complications, for example, pneumonia. Home remedies and over-the-counter (OTC) drugs used for the treatment of the signs and symptoms of colds and the flu may affect blood sugar levels in people with diabetes.Some medications are OK to take if you have diabetes get a cold or the flu include nonsteroidal anti-inflammatory drugs or NSAIDs, like acetaminophen (Tylenol) and ibuprofen (Motrin) to control symptoms of fever and pain. Most cough syrups are safe to take; however, check with your pediatrician to see what medications are safe to give your child if he or she has type 1 or 2 diabetes. If you have diabetes and are sick with a cold or flu, you need to check your blood sugar levels more frequently. Continue taking your regular medications. Eat a diabetic low-glycemic index diet rich in antioxidants. To prevent colds and the flu drink at least eight 8 ounce glasses of water a day. To replenish fluids, drink sports drinks like Gatorade and Pedialyte to replenish electrolytes. Avoid people who are sick, sneezing, coughing, or have other symptoms of a cold or flu.
-
Type 1 Diabetes (Symptoms, Causes, Diet, Treatment, Life Expectancy)
Type 1 diabetes mellitus (juvenile) is an auto-immune disease with no known cause at this time, although there are a few risk factors. Symptoms of type 1 diabetes include frequent urination, unintentional weight loss, dry and itchy skin, vision problems, wounds that heal slowly, and excessive thirst. Type 1 diabetes is diagnosed with blood tests. A healthy lifestyle and controlling blood glucose levels can improve life expectancy.
-
Gestational Diabetes (Diabetes during Pregnancy))
Learning how to avoid gestational diabetes is possible and maintaining a healthy weight and diet before and during pregnancy can help. Discover risk factors, tests and treatments for, and signs and symptoms of gestational diabetes.
-
How to Prevent Diabetes Naturally
Prediabetes is a condition in which a person has early symptoms of diabetes, but has not yet fully developed the condition. If prediabetes is not treated with lifestyle changes, the person could develop type 2 diabetes. Type 2 diabetes and prediabetes can be prevented with lifestyle changes, for example, eating a healthy diet, getting more exercise, reducing stress, quitting smoking, reducing or managing blood pressure and cholesterol, and managing any other health conditions or risk factors that you may have for developing type 2 diabetes.
-
Diabetes Foot Problems
Diabetes related foot problems can affect your health with two problems: diabetic neuropathy, where diabetes affects the nerves, and peripheral vascular disease, where diabetes affects the flow of blood. Common foot problems for people with diabetes include athlete's foot, fungal infection of nails, calluses, corns, blisters, bunions, dry skin, foot ulcers, hammertoes, ingrown toenails, and plantar warts.
-
Eye Problems and Diabetes
Diabetes and eye problems are generally caused by high blood sugar levels over an extended period of time. Types of eye problems in a person with diabetes include glaucoma, cataracts, and retinopathy. Examples of symptoms include blurred vision, headaches, eye aches, pain, halos around lights, loss of vision, watering eyes. Treatment for eye problems in people with diabetes depend on the type of eye problem. Prevention of eye problems include reducing blood pressure, cholesterol levels, quitting smoking, and maintaining proper blood glucose levels.
-
Types of Diabetes Type 2 Medications
Type 2 diabetes oral medications are prescribed to treat type 2 diabetes in conjuction with lifestyle changes like diet and exercise. There are nine classes of drugs approved for the treatment of type 2 diabetes. Examples of type 2 oral diabetes medications include acarbose (Precose), chlorpropamide (Diabinese), glipizide (Glucotrol, Glucotrol XL), and metformin (Glucophage). Side effects, drug interactions, warnings and precautions, dosage, and breastfeeding and pregnancy safety information should be reviewed prior to taking any medication.
-
Tips for Managing Type 1 and 2 Diabetes at Home
Managing your diabetes is a full time commitment. The goal of diabetic therapy is to control blood glucose levels and prevent the complications of diabetes. Information about exercise, diet, and medication will help you manage your diabetes better. Blood glucose reagent strips, blood glucose meters, urine glucose tests, tests for urinary ketones, continuous glucose sensors, and Hemoglobin A1C testing information will enable you to mange your diabetes at home successfully.
Treatment & Diagnosis
- Diabetes
- Gestational Diabetes
- Diabetes: Dealing with the Complications
- Diabetes: The Doctor is In: Discussing Diabetes -- Brunilda Nazario, MD -- 03/18/03
- Diabetes: Monitoring Your Sugar Levels
- Diabetes: Meeting the Diabetes Challenge
- Diabetes: Maintaining Control with Nutrition
- Diabetes & Fitness: Get Moving!
- Diabetes Alert Day
- Diabetes Update 2005
- Diabetes: Scientific Research for Type I Diabetes
- Diabetes Update -- Brunilda Nazario, MD
- Diabetes: Your Guide to Life With Diabetes
- Diabetes- Keeping Watch: Daily Diabetes Monitoring
- Diabetes and the Holidays: Eating Well-- Elaine Magee, MPH, RD-- 11/19/03
- Diabetes: Maintaining Control
- Diabetes and Your Heart
- Diabetes and Diet: What Do I Eat?
- Diabetes: Dealing with Your New Diagnosis
- Diabetes: Your Treatment Options
- Diabetes: Psychological Challenges
- Diabetes FAQs
- Type 2 Diabetes FAQs
- Type 1 Diabetes FAQs
- Gee - Whats in a Name
- Diabetes - An Aspirin A Day
- Diabetes and Eye Disease...See No Evil
- Diabetes - David Meets Goliath
- Insulin...Getting Better All the Time
- Exercise Therapy in Type 2 Diabetes - Part 1
- Exercise Therapy in Diabetes - Part 2
- Insulin Resistance - Keypoints
- Diabetes Mellitus - The Work Pays Off
- Diabetes - Foot Care: A Walking Matter
- Ramipril, Heart Disease, Stroke & Diabetes
- Diabetes Type I...Insulin Therapy
- Heart Disease Stroke and Diabetes
- Hypoglycemia (Low Blood Sugar) Symptoms and Diabetes
- Rheumatoid Arthritis & Diabetes Gene (PTPN22)
- Diabetes Report From The National ADA Meeting 2003
- Diabetes Update - American Diabetes Association 2006
- What Foods to Eat to Reverse Diabetes
- How Bad Is Type 1 Diabetes?
- What Causes Type 1 Diabetes in Adults?
- Is Type 1 Diabetes Genetic?
- What Will Happen if Type 1 Diabetes Is Left Untreated?
- Can You Get Diabetes from Stress?
- How Do You Know if You Have Diabetes?
- Does Celiac Disease Cause Diabetes?
- Can oral diabetes medications cause impotence?
- Does Diabetes Cause Gum Disease?
- What Is the Treatment for Diabetes Eye Damage?
- Does Anti-Retroviral Therapy for HIV Cause Diabetes?
- Can You Have Type 1 Diabetes Without Symptoms?
- 6 Frequently Asked Diabetes Question
- What Kind of Candy Can You Eat With Diabetes?
- Is Weight Loss Caused by Diabetes Dangerous?
- Can Diabetes Cause Muscle Pain?
- 11 Diabetes Diet Tips for the Holidays
- Diabetes Diet
- Top 10 Questions to Ask Your Doctor About Diabetes
- Prediabetes Symptoms and Diagnosis
- Diabetes: Eating Well with Type 2 Diabetes
- Diabetes: What Can I Eat?
Medications & Supplements

Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.