What is aluminum hydrochloride, and how does it work (mechanism of action)?

Aluminum hydrochloride is an astringent used in over-the-counter deodorants and antiperspirants. It is a powerful antiperspirant used for treating hyperhidrosis (excessive sweating). Aluminum hydrochloride works by reducing the activity of sweat glands and may also shrink sweat glands.

What brand names are available for aluminum hydrochloride?

Drisol, Certain Dri, Hydrosol, Xerac AC, Hypercare Solution

Is aluminum hydrochloride available as a generic drug?


Do I need a prescription for aluminum hydrochloride?


What are the uses for aluminum hydrochloride?

: Aluminum hydrochloride is used for treating hyperhidrosis (excessive perspiration).

What are the side effects of aluminum hydrochloride?

: The most common side effects of aluminum hydrochloride are:

  • Irritation of the skin
  • Itching
  • Tingling of the skin

Possible serious side effects of aluminum hydrochloride include signs and symptoms of allergic reactions such as:

  • Hives
  • Difficulty breathing
  • Swelling of face, lips, tongue, or throat
  • People who are sensitive or allergic to aluminum chloride should not use it.

What is the dosage for aluminum hydrochloride?

: Aluminum hydrochloride should be applied to affected areas once daily (for example, to the armpit, soles of feet, or palms) at bedtime. The frequency may be reduced to 1 to 2 times weekly as sweating decreases.

Aluminum hydrochloride is for topical use only and should not be applied to broken, irritated, or recently shaved skin.

It may damage certain metals and fabrics and it should not be used near an open flame.

Which drugs or supplements interact with aluminum hydrochloride?

: There are no drug interactions listed for aluminum hydrochloride.

Is aluminum hydrochloride safe to take if I'm pregnant or breastfeeding?


Use of aluminum hydrochloride during pregnancy has not been adequately evaluated.

It is not known whether aluminum hydrochloride is excreted in breast milk.

What else should I know about aluminum hydrochloride?

What preparations of aluminum hydrochloride are available?

PREPARATIONS: Solution: 6.25 and 20%

How should I keep aluminum hydrochloride stored?

STORAGE: Aluminum hydrochloride should be stored at room temperature, 20 C to 25 C (68 F to 77 F).


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Aluminum hydrochloride (Drisol, Certain Dri) is sold in solution or in over-the-counter deodorants and antiperspirants. Aluminum hydrochloride is uses to prevent sweating by reducing the activity and perhaps shrinking the sweat glands.

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Medscape, Aluminum Chloride Product Information