- Type 2 Diabetes: Learn the Warning Signs
- Diabetes Friendly Dining
- Type 2 Diabetes: Test Your Medical IQ
- What is lixisenatide, and how does it work?
- What brand names are available for lixisenatide?
- Is lixisenatide available as a generic drug?
- Do I need a prescription for lixisenatide?
- What are the uses for lixisenatide?
- What are the side effects of lixisenatide?
- What is the dosage for lixisenatide?
- Which drugs or supplements interact with lixisenatide?
- Is lixisenatide safe to use during pregnancy or while breastfeeding?
- What else should I know about lixisenatide?
What is lixisenatide, and how does it work?
- Lixisenatide is an injectable drug that reduces the level of sugar (glucose) in the blood. It is used for the treatment type 2 diabetes and is similar to
- Lixisenatide belongs in a class of drugs called incretin mimetics because these drugs mimic the effects of incretins. Incretins, such as human-glucagon-like peptide-1 (GLP-1), are hormones that are produced and released into the blood by the intestine in response to food. GLP-1 increases the secretion of insulin from the pancreas, slows absorption of glucose from the gut, and reduces the action of glucagon. (Glucagon is a hormone that increases glucose production by the liver.) All three of these actions reduce levels of glucose in the blood. In addition, GLP-1 reduces appetite. Lixisenatide is a synthetic (man-made) hormone that resembles and acts like GLP-1. In studies, lixisenatide treated patients achieved lower blood glucose levels and experienced weight loss.
What brand names are available for lixisenatide?
- Adlyxin is the brand name available for lixisenatide available in the US.
Quick GuideDiabetes Diet: Healthy Meal Plans for Diabetes-Friendly Eating
What are the uses for lixisenatide?
What are the side effects of lixisenatide?
Common side effects of include:
- Hypoglycemia (when combined with insulin or sulfonyrea)
Other possible side effects of include:
- Indigestion (dyspepsia)
- Upper abdominal pain
- Abdominal distension
- Abdominal pain
- Injection site reactions (pain, redness, itching)
Possible serious side effects of include:
Quick GuideDiabetes Diet: Healthy Meal Plans for Diabetes-Friendly Eating
What is the dosage for lixisenatide?
- The recommended starting dose of Adlyxin is 10 mcg injected under the skins (subcutaneously) once daily for 14 days.
- The dose should be increased on day 15 to the maintenance dose of 20 mcg once daily.
Which drugs or supplements interact with lixisenatide?
- Adlyxin slows down transit of food and drugs through the intestine and, therefore, may reduce the absorption of drugs that are taken by mouth. Caution should be used when combining Adlyxin with oral medications that have a narrow therapeutic ratio or that require careful monitoring. If these medications are to be taken with food they should be taken with a meal or snack when Adlyxin is not administered.
- Oral medications such as antibiotics, or medications, for example acetaminophen (Tylenol) whose effects shouldn't be delayed should be taken at least 1 hour before Adlyxin injection.
- Oral contraceptives should be taken at least 1 hour before Adlyxin administration or at least 11 hours after an injection of Adlyxin.
- Combining Adlyxin with insulin or drugs that stimulate release of insulin, for example, glyburide (Micronase, Diabeta, Glynase, Prestab) may increase the occurrence of low blood sugar (hypoglycemia). The dose of insulin or the insulin release stimulating drug should be reduced.
Is lixisenatide safe to use during pregnancy or while breastfeeding?
What else should I know about lixisenatide?
What preparations of lixisenatide are available?
- Injection (Prefilled Pen): 50, 100 mcg/mL
How should I keep lixisenatide stored?
- Adlyxin pen should be kept in the package to protect it from light and it should be stored in a refrigerator at 2 C to 8 C (36 F to 46 F) prior to use.
- It should not be frozen.
- After first use, it should be stored below 30 C (86 F).
- The pen cap should be replaced after each use to protect it from light.
- The pen should discarded 14 days after first use.
When was lixisenatide approved by the FDA?
- The FDA approved lixisenatide in July 2016.
REFERENCE: FDA Prescribing Information
Quick GuideDiabetes Diet: Healthy Meal Plans for Diabetes-Friendly Eating
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Top Adlyxin lixisenatide Related ArticlesComplete List
antidiabetics-oralType 2 diabetes oral medications are prescribed to treat type 2 diabetes in conjuction with lifestyle changes like diet and exercise. There are nine classes of drugs approved for the treatment of type 2 diabetes. Examples of type 2 oral diabetes medications include acarbose (Precose), chlorpropamide (Diabinese), glipizide (Glucotrol, Glucotrol XL), and metformin (Glucophage). Side effects, drug interactions, warnings and precautions, dosage, and breastfeeding and pregnancy safety information should be reviewed prior to taking any medication.
Diabetes and Eye ProblemsDiabetes and eye problems are generally caused by high blood sugar levels over an extended period of time. Types of eye problems in a person with diabetes include glaucoma, cataracts, and retinopathy. Examples of symptoms include blurred vision, headaches, eye aches, pain, halos around lights, loss of vision, watering eyes. Treatment for eye problems in people with diabetes depend on the type of eye problem. Prevention of eye problems include reducing blood pressure, cholesterol levels, quitting smoking, and maintaining proper blood glucose levels.
Diabetes and Kidney DiseaseIn the United States diabetes is the most common cause of kidney failure. High blood pressure and high levels of blood glucose increase the risk that a person with diabetes will eventually progress to kidney failure. Kidney disease in people with diabetes develops over the course of many years. albumin and eGFR are two key markers for kidney disease in people with diabetes. Controlling high blood pressure, blood pressure medications, a moderate protein diet, and compliant management of blood glucose can slow the progression of kidney disease. For those patients who's kidneys eventually fail, dialysis or kidney transplantation is the only option.
Diabetes Foot ProblemsLearn more about diabetes related foot problems. For people with diabetes, too much glucose in the blood can cause serious foot complications such as nerve damage, infection, and ulcers. Find tips for proper foot care to help prevent serious complications.
Diabetes MellitusDiabetes is a chronic condition characterized by high levels of sugar (glucose) in the blood. The two types of diabetes are referred to as type 1 (insulin dependent) and type 2 (non-insulin dependent). Symptoms of diabetes include increased urine output, thirst, hunger, and fatigue. Treatment of diabetes depends on the type.
Take the Diabetes QuizTake the Diabetes Quiz and learn the causes, signs, symptoms, and types of this growing epidemic. What does diabetes have to do with obesity and diet? Learn about life as a diabetic.
Diabetes TreatmentThe major goal in treating diabetes is controlling elevated blood sugar without causing abnormally low levels of blood sugar. Type 1 diabetes is treated with:
- and a diabetic diet.
- weight reduction,
- a diabetic diet,
- and exercise.
Diabetic Diet for Type 2 DiabetesA type 2 diabetes diet or a type 2 diabetic diet is important for blood sugar (glucose) control in people with diabetes to prevent complications of diabetes. There are a variety of type 2 diabetes diet eating plans such as:
- the Mediterranean diet,
- Paleo diet,
- ADA Diabetes Diet,
- and vegetarian diets.
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Foot Problems (Diabetes)Diabetes related foot problems can affect your health with two problems: diabetic neuropathy, where diabetes affects the nerves, and peripheral vascular disease, where diabetes affects the flow of blood. Common foot problems for people with diabetes include athlete's foot, fungal infection of nails, calluses, corns, blisters, bunions, dry skin, foot ulcers, hammertoes, ingrown toenails, and plantar warts.
Insulin Pump For Diabetes MellitusAn insulin pump is designed to deliver insulin directly to a patient with diabetes. They are about the size of a standard beeper. The pump is attached to under the skin (usually on the abdomen). The amount of insulin required will depend on lifestyle (exercise, sleep patterns, activity level, and diet).
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Type 2 Diabetes
Type 2 diabetes is a condition in which a person's pancreas does not produce enough insulin to meet the needs of the body. Causes of type 2 diabetes are a sedentary lifestyle, eating excess sugar and carbohydrates, lack of exercise, being overweight, and genetics. Symptoms of type 2 diabetes are often subtle, but may include:
- Urine odor
- Unintentional weight gain or loss
- Frequent urination
- Dark skin under the chin, armpits, or groin
Type 2 diabetes is diagnosed by a blood test. Treatment for type 2 diabetes are a healthy type 2 diabetes diet, exercise, stress reduction, and medication. Type 2 diabetes is a preventable disease. Incorporating healthy lifestyle changes (for example, eating a healthy diet, exercising more, and reducing stress) can prevent type 2 diabetes.
Type 2 Diabetes SlideshowLearn about type 2 diabetes warning signs, symptoms, diagnosis, and treatment options. Read how diet and exercise can help manage type 2 diabetes.
Urine Tests for DiabetesUrine tests for individuals with diabetes is important to check for diabetes-related kidney disease and severe hypoglycemia. With proper monitoring of blood glucose levels, diabetic-kidney disease can be avoided.