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- What is adapalene, and how does it work (mechanism of action)?
- What are the uses for adapalene?
- What are the side effects of adapalene?
- What is the dosage for adapalene?
- Which drugs or supplements interact with adapalene?
- Is adapalene safe to take if I'm pregnant or breastfeeding?
- What else should I know about adapalene?
What is adapalene, and how does it work (mechanism of action)?
Adapalene is a gel used for the treatment of acne vulgaris (pimples). The exact mechanism of action is not known. Scientists believe that when adapalene is applied to the skin, it affects the growth of skin cells and thereby reduces the formation of pimples.
What brand names are available for adapalene?
Is adapalene available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for adapalene?
What are the uses for adapalene?
What are the side effects of adapalene?
The most common side effects of adapalene are:
Most of these side effects lessen with continued use; however, if they are bothersome, decreasing the frequency with which adapalene is applied may reduce these side effects.
Adapalene may increase the sensitivity of the skin to sun and lead to sunburn. Excessive sun exposure should be avoided, and sunscreens should be used over the treated areas if exposure to the sun cannot be avoided. Adapalene should not be applied to sunburned skin, cuts, eyes, nose, or lips.
What is the dosage for adapalene?
Wash and dry the affected areas. Apply a thin layer of gel to the affected areas once daily at bedtime. Avoid the eyes, lips and nose. There may be a worsening of acne during the first few weeks of therapy because adapalene promotes the growth of pimples that have begun to form but are not yet visible. Therefore, treatment should not be stopped if acne appears to be worsening. Beneficial effects should be seen by 8 to 12 weeks.
Which drugs or supplements interact with adapalene?
Excessive skin irritation may occur if adapalene is used with other acne medications.
Is adapalene safe to take if I'm pregnant or breastfeeding?
Only very small amounts of adapalene are absorbed through skin and into the body. However, there are no adequate studies in pregnant women.
It is not known whether adapalene is excreted in breast milk.
What else should I know about adapalene?
What preparations of adapalene are available?
How should I keep adapalene stored?
Store at room temperature, 20 C - 25 C (68 F - 77 F)
Latest Skin News
Adapalene (Differin) is a gel prescribed for the treatment of acne (pimples). Review side effects (sun sensitivity, for example), drug interactions, pregnancy safety information, and dosage prior to taking any medication.
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Rosacea Quiz: Test Your Medical IQ
Think acne and rosacea are the same? Think again. Take the Rosacea Quiz to learn all about this inflammatory skin condition.
Acne (Pimples) Quiz: Test Your Medical IQ
Acne is the most common skin disorder in the world. If you suffer from acne, you are not alone and many treatment options are...
Related Disease Conditions
Acne is a localized skin inflammation as a result of overactivity of oil glands at the base of hair follicles. This inflammation, depending on its location, can take the form of a superficial pustule (contains pus), a pimple, a deeper cyst, congested pores, whiteheads, or blackheads. Treatments vary depending on the severity of the acne.
Rosacea is a skin disease that causes redness of the forehead, chin, and lower half of the nose. In addition to inflammation of the facial skin, symptoms include dilation of the blood vessels and pimples (acne rosacea) in the middle third of the face. Oral and topical antibiotics are treatments for rosacea. If left untreated, rhinophyma (a disfiguring nose condition) may result.
Heart Attack Prevention
Heart disease and heart attacks can be prevented by leading a healthy lifestyle with diet, exercise, and stress management. Symptoms of heart attack in men and women include chest discomfort and pain in the shoulder, neck, jaw, stomach, or back. Women experience the same symptoms as men; however, they also may experience: Extreme fatigue Pain in the upper abdomen Dizziness Fainting Leading a healthy lifestyle with a heart healthy low-fat diet, and exercise can help prevent heart disease and heart attack.
Freckles are flat circular spots on the skin that may be red, yellow, tan, light brown, brown, or black in color. Lentigo is the term used to describe certain types of darker freckles. Ephelis typically appear during the sunny months. Freckles can be prevented with sunscreens, the use of wide-brimmed hats, sun-protective clothing, avoiding peak sun hours, and seeking shade and staying indoors.
Keratosis Pilaris (KP)
Keratosis pilaris (KP) is a common skin disorder in which small white or red bumps appear around hair follicles on the upper arms, thighs, buttocks, and cheeks. The cause of KP is unknown. There is no cure for keratosis pilaris, and the condition may resolve on its own. Gentle exfoliation, professional manual extraction, chemical peels, and microdermabrasion, along with topical products, are the best treatments for this condition.
Melasma is a patchy brown discoloration of the skin on the face. When it occurs in pregnancy, it's called chloasma. Melasma is commonly treated with hydroquinone creams.
Cystic acne is distinguised by painful nodules on the chest, face, neck, and back. This form of acne is known to scar. Treatment may incorporate the use of hormonal therapies, oral antibiotics, and prescription medications.
Treatment & Diagnosis
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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.