Reviewed on 6/11/2021
Other Name(s):

Acacia arabica, Acacia senegal, Acacia verek, Arbre à Gomme Arabique, Bum Senegal, Bomme Arabique, Bomme de Senegal, Bummae Momosae, Goma Arábiga, Gomme Acacia, Gomme Arabique, Gomme d'Acacia, Gomme Sénégal, Gommier Blanc, Gum Acacia, Gum Arabic, Khadir, Kher, Kumatia, Mimosa senegal, Senegalia senegal.


Acacia is the gum that is exuded from the acacia tree. It's a dietary fiber that can dissolve in water.

As a medicine, acacia is taken by mouth to reduce cholesterol levels and to help increase weight loss.

In manufacturing, acacia is used as a pharmaceutical ingredient in medications for throat or stomach inflammation and as a film-forming agent in peel-off skin masks.

Don't confuse acacia with sweet acacia (Acacia farnesiana).

How does it work?

Acacia is a source of dietary fiber. It tends to make people feel full, so they might stop eating earlier than they otherwise would. This might lead to weight loss and reduced cholesterol levels.


Vitamin D Deficiency: How Much Vitamin D Is Enough? See Slideshow

Uses & Effectiveness

Possibly Ineffective for...

  • High cholesterol. Taking acacia by mouth does not seem to lower cholesterol levels.

Insufficient Evidence to Rate Effectiveness for...

  • Dental plaque. Early research suggests that chewing acacia gum for 10 minutes five times daily for 7 days reduces dental plaque more than sugar-free chewing gum.
  • Weight loss. There is early evidence that shows taking 30 grams of powdered acacia daily might help weight loss.
More evidence is needed to rate the effectiveness of acacia for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

Side Effects

Acacia is LIKELY SAFE for most adults when taken by mouth in amounts commonly found in food.

Acacia is POSSIBLY SAFE when taken by mouth in amounts used for medical purposes. Up to 30 grams daily has been used safely for 6 weeks. However, it can cause minor adverse effects, including gas, bloating, nausea, and loose stools.


Next to red peppers, you can get the most vitamin C from ________________. See Answer

Special Precautions & Warnings

Pregnancy and breast-feeding: Not enough is known about the use of acacia during pregnancy and breast-feeding. Stay on the safe side and avoid use.


Amoxicillin (Amoxil, Trimox)Interaction Rating: Major Do not take this combination.

Acacia can prevent the body from absorbing the antibiotic amoxicillin (Amoxil, Trimox). To prevent this interaction, take acacia at least four hours before or after taking amoxicillin (Amoxil, Trimox).


The appropriate dose of acacia depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for acacia. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

FDA Logo

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Health Solutions From Our Sponsors


Al Mustafa, Z. H. and Dafallah, A. A. A study on the toxicology of Acacia nilotica. Am J Chin Med 2000;28(1):123-129. View abstract.

Baratawidjaja, I. R., Baratawidjaja, P. P., Darwis, A., Soo-Hwee, L., Fook-Tim, C., Bee-Wah, L., and Baratawidjaja, K. G. Prevalence of allergic sensitization to regional inhalants among allergic patients in Jakarta, Indonesia. Asian Pac.J Allergy Immunol. 1999;17(1):9-12. View abstract.

Bener, A., Safa, W., Abdulhalik, S., and Lestringant, G. G. An analysis of skin prick test reactions in asthmatics in a hot climate and desert environment. Allerg.Immunol.(Paris) 2002;34(8):281-286. View abstract.

Boral, D., Chatterjee, S., and Bhattacharya, K. The occurrence and allergising potential of airborne pollen in West Bengal, India. Ann.Agric.Environ.Med 2004;11(1):45-52. View abstract.

Correia, O., Barros, M. A., and Mesquita-Guimaraes, J. Airborne contact dermatitis from the woods Acacia melanoxylon and Entandophragma cylindricum. Contact Dermatitis 1992;27(5):343-344. View abstract.

Cvitanovic, S., Znaor, L., Perisic, D., and Grbic, D. Hypersensitivity to pollen allergens on the Adriatic coast. Arh.Hig.Rada Toksikol. 2004;55(2-3):147-154. View abstract.

De Zotti, R. and Gubian, F. Asthma and rhinitis in wooding workers. Allergy Asthma Proc 1996;17(4):199-203. View abstract.

Deferme, S., Kamuhabwa, A., Nshimo, C., de Witte, P., and Augustijns, P. Screening of Tanzanian plant extracts for their potential inhibitory effect on P-glycoprotein mediated efflux. Phytother Res 2003;17(5):459-464. View abstract.

Final report of the safety assessment of Acacia catechu gum, Acacia concinna fruit extract, Acacia dealbata leaf extract, Acacia dealbata leaf wax, Acacia decurrens extract, Acacia farnesiana extract, Acacia farnesiana flower wax, Acacia farnesiana gum, Acacia senegal extract, Acacia senegal gum, and Acacia senegal gum extract. Int J Toxicol 2005;24 Suppl 3:75-118. View abstract.

Gazi, M. I. The finding of antiplaque features in Acacia Arabica type of chewing gum. J Clin Periodontol. 1991;18(1):75-77. View abstract.

Geller, M. and Rosario, N. A. Skin test sensitivity to Acacia pollen in Brazil. Ann.Allergy 1981;47(3):180-181. View abstract.

Goussault, Y., Sharif, A., and Bourrillon, R. Serum albumin biosynthesis and secretion by resting and lectin stimulated human lymphocytes. Biochem Biophys Res Commun. 12-20-1976;73(4):1030-1035. View abstract.

Haridas, V., Arntzen, C. J., and Gutterman, J. U. Avicins, a family of triterpenoid saponins from Acacia victoriae (Bentham), inhibit activation of nuclear factor-kappaB by inhibiting both its nuclear localization and ability to bind DNA. Proc Natl.Acad.Sci U.S.A 9-25-2001;98(20):11557-11562. View abstract.

Haridas, V., Hanausek, M., Nishimura, G., Soehnge, H., Gaikwad, A., Narog, M., Spears, E., Zoltaszek, R., Walaszek, Z., and Gutterman, J. U. Triterpenoid electrophiles (avicins) activate the innate stress response by redox regulation of a gene battery. J Clin Invest 2004;113(1):65-73. View abstract.

Hausen, B. M. Sensitizing capacity of naturally occurring quinones. V. 2.6-dimethoxy-p-benzoquinone: occurrence and significance as a contact allergen. Contact Dermatitis 1978;4(4):204-213. View abstract.

Hausen, B. M., Bruhn, G., and Tilsley, D. A. Contact allergy to Australian blackwood (Acacia melanoxylon R.Br.): isolation and identification of new hydroxyflavan sensitizers. Contact Dermatitis 1990;23(1):33-39. View abstract.

Jayatilake, G. S., Freeberg, D. R., Liu, Z., Richheimer, S. L., Blake Nieto, M. E., Bailey, D. T., Haridas, V., and Gutterman, J. U. Isolation and structures of avicins D and G: in vitro tumor-inhibitory saponins derived from Acacia victoriae. J Nat Prod. 2003;66(6):779-783. View abstract.

Joshi, L., Van Eck, J. M., Mayo, K., Di Silvestro, R., Blake Nieto, M. E., Ganapathi, T., Haridas, V., Gutterman, J. U., and Arntzen, C. J. Metabolomics of plant saponins: bioprospecting triterpene glycoside diversity with respect to mammalian cell targets. OMICS. 2002;6(3):235-246. View abstract.

Kwaasi, A. A., Harfi, H. A., Parhar, R. S., Saleh, S., Collison, K. S., Panzani, R. C., Al Sedairy, S. T., and Al Mohanna, F. A. Cross-reactivities between date palm (Phoenix dactylifera L.) polypeptides and foods implicated in the oral allergy syndrome. Allergy 2002;57(6):508-518. View abstract.

Lemonnier, M., Goussault, Y., and Bourrillon, R. [Interactions of phytoagglutinins with urinary glycopeptides. Analysis of a glycopeptide inhibitor of phytoagglutinin from Robinia pseudo acacia]. Carbohydr Res 1972;24(2):323-331. View abstract.

Lewis, W. H. and Vinay, P. North American pollinosis due to insect-pollinated plants. Ann.Allergy 1979;42(5):309-318. View abstract.

Li, S. S., Gao, Z., Feng, X., Jones, S. H., and Hecht, S. M. Plant sterols as selective DNA polymerase beta lyase inhibitors and potentiators of bleomycin cytotoxicity. Bioorg.Med Chem 8-1-2004;12(15):4253-4258. View abstract.

Liam, C. K., Loo, K. L., Wong, C. M., Lim, K. H., and Lee, T. C. Skin prick test reactivity to common aeroallergens in asthmatic patients with and without rhinitis. Respirology. 2002;7(4):345-350. View abstract.

Lo, Y. L., Hsu, C. Y., and Huang, J. D. Comparison of effects of surfactants with other MDR reversing agents on intracellular uptake of epirubicin in Caco-2 cell line. Anticancer Res 1998;18(4C):3005-3009. View abstract.

Padula, P. A. and Friedmann, L. W. Acquired amputation and prostheses before the sixteenth century. Angiology 1987;38(2 Pt 1):133-141. View abstract.

Paufique, L. and Hugonnier, R. [Recurrent iridocyclitis caused by an acacia thorn in the ciliary body. Technic for the extraction of the foreign body]. Bull.Soc Ophtalmol.Fr. 1966;66(5):547-549. View abstract.

Pumhirun, P., Towiwat, P., and Mahakit, P. Aeroallergen sensitivity of Thai patients with allergic rhinitis. Asian Pac.J Allergy Immunol. 1997;15(4):183-185. View abstract.

Raghuprasad, P. K., Brooks, S. M., Litwin, A., Edwards, J. J., Bernstein, I. L., and Gallagher, J. Quillaja bark (soapbark)--induced asthma. J Allergy Clin Immunol. 1980;65(4):285-287. View abstract.

Sam, C. K., Kesavan, Padmaja, Liam, C. K., Soon, S. C., Lim, A. L., and Ong, E. K. A study of pollen prevalence in relation to pollen allergy in Malaysian asthmatics. Asian Pac.J Allergy Immunol. 1998;16(1):1-4. View abstract.

Shah, B. H., Safdar, B., Virani, S. S., Nawaz, Z., Saeed, S. A., and Gilani, A. H. The antiplatelet aggregatory activity of Acacia nilotica is due to blockade of calcium influx through membrane calcium channels. Gen.Pharmacol 1997;29(2):251-255. View abstract.

Singh, G., Bala, N., Rathod, T. R., and Singh, B. Effect of textile industrial effluent on tree plantation and soil chemistry. J Environ.Biol 2001;22(1):59-66. View abstract.

Singh, K. N., Mettal, R. K., and Barthwal, K. C. Hypoglycemia activity of Acacia catechu, Acacia suma, and Albizzia Odoratisima seed diets in normal albino rats. Indian J Med Res 1976;64(5):754-757.

Suliaman, F. A., Holmes, W. F., Kwick, S., Khouri, F., and Ratard, R. Pattern of immediate type hypersensitivity reactions in the Eastern Province, Saudi Arabia. Ann.Allergy Asthma Immunol. 1997;78(4):415-418. View abstract.

Thorburn, A. W., Brand, J. C., Cherikoff, V., and Truswell, A. S. Lower postprandial plasma glucose and insulin after addition of Acacia coriacea flour to wheat bread. Aust N Z J Med 1987;17(1):24-26. View abstract.

Tilsley, D. A. Australian blackwood dermatitis. Contact Dermatitis 1990;23(1):40-41. View abstract.

Wood-Baker, R. and Markos, J. Occupational asthma due to blackwood (Acacia Melanoxylon). Aust N Z J Med 1997;27(4):452-453. View abstract.

Babiker R, Merghani TH, Elmusharaf K, et al. Effects of gum Arabic ingestion on body mass index and body fat percentage in healthy adult females: two-arm randomized, placebo controlled, double-blind trial. Nutr J 2012;11:111. View abstract.

Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at:

Eltayeb IB, Awad AI, Elderbi MA, Shadad SA. Effect of gum arabic on the absorption of a single oral dose of amoxicillin in healthy Sudanese volunteers. J Antimicrob Chemother 2004;54:577-8. View abstract.

Fotisch K, Fäh J, Wüthrich B, et al. IgE antibodies specific for carbohydrates in a patient allergic to gum arabic (Acacia senegal). Allergy. 1998 Nov;53(11):1043-51. View abstract.

Howlett BJ, Hill DJ, Knox RB. Cross-reactivity between Acacia (wattle) and rye grass pollen allergens. Detection of allergens in Acacia (wattle) pollen. Clin Allergy. 1982 May;12(3):259-68. View abstract.

Jensen CD, Haskell W, Whittam JH. Long-term effects of water-soluble dietary fiber in the management of hypercholesterolemia in healthy men and women. Am J Cardiol 1997;79:34-7. View abstract.

Jensen CD, Spiller GA, Gates JE, et al. The effect of acacia gum and a water-soluble dietary fiber mixture on blood lipids in humans. J Am Coll Nutr 1993;12:147-54. View abstract.

Lust J. The herb book. New York, NY: Bantam Books, 1999.