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- What brand names are available for zidovudine?
- Is zidovudine available as a generic drug?
- Do I need a prescription for zidovudine?
- What are the uses for zidovudine?
- What are the side effects of zidovudine?
- What is the dosage for zidovudine?
- Which drugs or supplements interact with zidovudine?
- Is zidovudine safe to take if I'm pregnant or breastfeeding?
- What else should I know about zidovudine?
What is the dosage for zidovudine?
- For the treatment of HIV infection the recommended oral dose for adults is 100 mg every 4 hours. The intravenous dose is 1 to 2 mg/kg every 4 hours.
- For children 3 months to 12 years old, the oral starting dose is 180 mg/m2 every 6 hours not to exceed 200 mg every 6 hours.
- Infants should be given 2 mg/kg orally every 6 hours within 12 hours of birth and for 6 weeks or 1.5 mg/kg intravenously every 6 hours.
- To prevent HIV transmission from mother to fetus, the dose is 100 mg five times daily or 200 mg three times daily.
- Treatment should be initiated between the 14th and 34th weeks of pregnancy and continued until the time of labor.
- During labor and delivery, 2mg/kg should be administered intravenously over 1 hr followed by 1 mg/kg/hr until the umbilical cord is clamped.
Which drugs or supplements interact with zidovudine?
- Fluconazole (Diflucan), probenecid and trimethoprim (Trimpex) reduce the elimination of zidovudine and therefore increase the blood concentration of zidovudine. This can lead to increased side effects from zidovudine.
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