PRECAUTIONS: Tell your doctor your medical history, especially of: pancreatic disease, peripheral neuropathy (tingling of the hands or feet), heart problems, liver problems, kidney problems, major infections/injuries/surgeries, alcohol usage, allergies (especially drug allergies). Avoid alcohol. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if zalcitabine is excreted into breast milk. Avoid breast-feeding in order to protect the newborn from possible HIV transmission.

DRUG INTERACTIONS: This drug should not be used with the following medications because very serious interactions may occur: lamivudine. If you are currently using lamivudine, tell your doctor or pharmacist before starting zalcitabine. Tell your doctor of all prescription and nonprescription drugs you may use, especially of: chloramphenicol, cisplatin, dapsone, disulfiram, ethionamide, glutethimide, gold, hydralazine, iodoquinol, phenytoin, ribavirin, nitrofurantoin, isoniazid, metronidazole, vincristine. Food decreases the absorption of this drug. Follow your doctor's instructions with regard to eating and taking this drug. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

NOTES: Blood tests should be done routinely to monitor for anemia and to ensure it is working properly. This medication is very potent and should not be shared.

MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is within 2 hours of the next dose, skip the missed dose and resume your usual dosing schedule. It is important not to miss doses of this drug.

STORAGE: Store at room temperature away from sunlight and moisture.

MEDICAL ALERT: Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).

Last Editorial Review: 3/2/2005

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