WITCH HAZEL (Hamamelis virginiana) - ORAL side effects, medical uses, and drug interactions.

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GENERIC NAME: WITCH HAZEL (Hamamelis virginiana) - ORAL

USES: Witch hazel leaf has been used for relieving symptoms of varicose veins and hemmorhoids. It has also been used for relieving diarrhea. Some herbal/diet supplement products have been found to contain possibly harmful impurities/additives. Check with your pharmacist for more details regarding the particular brand you use. The FDA has not reviewed this product for safety or effectiveness. Consult your doctor or pharmacist for more details.

HOW TO USE: Take this product by mouth as directed. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist. If your condition persists or worsens, or if you think you may have a serious medical problem, seek immediate medical attention.

SIDE EFFECTS: Stomach upset, nausea, vomiting and constipation may occur. If any of these effects persist or worsen, contact your doctor promptly. Tell your doctor immediately if you have any of these highly unlikely but very serious side effects: stomach pain, yellowing eyes or skin, dark urine. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Liquid forms of this product may contain alcohol. Ask your pharmacist about the safe use of this product, use with other medications and use with alcoholic beverages. Hamamelis leaf is not recommended for use during pregnancy. Consult your doctor before using this product. Because of the potential risk to the infant, breast-feeding while using this product is not recommended. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Before using this product, tell your doctor or pharmacist of all prescription and nonprescription medications you may use.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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Important Safety Information

KAPIDEX may not be right for everyone. You should not take KAPIDEX if you are allergic to KAPIDEX or any of its ingredients. Severe allergic reactions have been reported.

Symptom relief does not rule out other serious stomach conditions.

The most common side effects of KAPIDEX were diarrhea (4.8%), stomach pain (4.0%), nausea (2.9%), common cold (1.9%), vomiting (1.6%), and gas (1.6%). KAPIDEX and certain other medicines can affect each other. Before taking KAPIDEX, tell your doctor if you are taking ampicillin, atazanavir, digoxin, iron, ketoconazole, or tacrolimus. If you are taking KAPIDEX with warfarin, you may need to be monitored because serious risks could occur.

Uses of KAPIDEX

Persistent heartburn two or more days a week, despite treatment and diet changes, could be acid reflux disease (ARD). Prescription KAPIDEX capsules are used in adults to treat heartburn related to ARD, to heal acid-related damage to the lining of the esophagus (called erosive esophagitis or EE), and to stop EE from coming back. Individual results may vary. Most damage (erosions) heals in 4�8 weeks.

Talk to your doctor or healthcare professional. Please see full Prescribing Information for KAPIDEX.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

KAPIDEX™ is a trademark of Takeda Pharmaceuticals North America, Inc., and is used under license by Takeda Pharmaceuticals America, Inc.

LPD-00767

GENERIC NAME: WITCH HAZEL (Hamamelis virginiana) - ORAL

One Pill a Day: Up to 24 Hours of Heartburn Relief in Many Adults with ARD

Important Safety Information

Uses of KAPIDEX

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