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It may cause stomach upset and digestive system upset. It can also cause itching, rash, and allergic reactions, particularly in people allergic to aspirin.
Special Precautions & Warnings:Pregnancy and breast-feeding: Not enough is known about the safety of using willow bark during pregnancy. It's best to avoid using it.
Using willow bark while breast-feeding is POSSIBLY UNSAFE. Willow bark contains chemicals that can enter breast milk and have harmful effects on the nursing infant. Don't use it if you are breast-feeding.
Children: Willow bark is POSSIBLY UNSAFE n children when taken by mouth for viral infections such as colds and flu. There is some concern that, like aspirin, it might increase the risk of developing Reye's syndrome. Stay on the safe side and don't use willow bark in children.
Bleeding disorders: Willow bark might increase the risk of bleeding in people with bleeding disorders.
Kidney disease: Willow bark might reduce blood flow through the kidneys, which might lead to kidney failure in certain people. If you have kidney disease, don't use willow bark.
Sensitivity to aspirin: People with ASTHMA, STOMACH ULCERS, DIABETES, GOUT, HEMOPHILIA, HYPOPROTHROMBINEMIA, or KIDNEY or LIVER DISEASE might be sensitive to aspirin and also willow bark. Using willow bark might cause serious allergic reactions. Avoid use.
Surgery: Willow bark might slow blood clotting. There is a concern it could cause extra bleeding during and after surgery. Stop using willow bark at least 2 weeks before a scheduled surgery.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.