GENERIC NAME: warfarin
BRAND NAME: Coumadin, Jantoven
GENERIC AVAILABLE: Yes
- Warfarin is used in treating patients with deep vein thrombosis (DVT) to prevent extension of the clot, and to reduce the risk of pulmonary embolism.
- Patients with pulmonary embolism are treated with warfarin to prevent further emboli.
- Warfarin also is used in patients with atrial fibrillation or artificial heart valves to reduce the risk of strokes, and after a heart attack.
- It also is helpful in preventing blood clots from forming in certain orthopedic surgeries such as knee or hip replacements.
- Warfarin is used in preventing closure of coronary artery stents due to clotting.
BLACK BOX WARNING:
- Warfarin causes cause major or fatal bleeding. Warfarin treatment should be monitored regularly using the INR test. Drugs, dietary changes, and other factors affect INR levels and warfarin therapy. Patients should be trained on how to reduce the risk of bleeding and to report signs and symptoms of bleeding.
The two most serious side effects of warfarin are:
- Necrosis (gangrene) of the skin
Bleeding can occur in any organ or tissue. Bleeding around the brain can cause severe headache and paralysis. Bleeding in the joints can cause joint pain and swelling. Bleeding in the stomach or intestines can cause weakness, fainting spells, black tarry stools, vomiting of blood, or coffee ground material. Bleeding in the kidneys can cause back pain and blood in urine.
Other side effects include:
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