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Medications and Drugs

GENERIC NAME: WARFARIN - ORAL (WARF-uh-rin)

BRAND NAME(S): Coumadin

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage | Medical Alert

USES: Warfarin is used to prevent and treat harmful blood clots. This medication helps to keep blood flowing smoothly in your body by decreasing the amount of clotting proteins in the blood. Warfarin is sometimes commonly referred to as a "blood thinner," but its more correct term is "anticoagulant." Conditions which increase your risk of developing blood clots include a certain type of irregular heart rhythm (atrial fibrillation), heart valve replacement, or a recent heart attack. Preventing harmful blood clots helps to reduce the risk of a stroke or heart attack.

HOW TO USE: Take this medication by mouth usually once a day, or as directed by your doctor. It is very important to take it exactly as prescribed. Do not increase the dose, take it more frequently, or stop using it unless directed by your doctor. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time each day. The dosage is based on your medical condition and response to therapy. Laboratory tests (prothrombin time-PT and international normalized ratio-INR) will be performed periodically to monitor your response to therapy and your dose may be adjusted based on the results.

SIDE EFFECTS: Nausea, vomiting, loss of appetite, stomach/abdominal bloating or cramps may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. This medication can cause bleeding if its effect on your blood clotting proteins is too much (unusually high PT and INR results). Even if your doctor stops your medication, this risk can persist for up to a week. Tell your doctor immediately if any of these signs of serious bleeding occur: unusual pain/swelling/discomfort, prolonged bleeding from cuts or gums, persistent nosebleeds, unusually heavy or prolonged menstrual flow, unusual or easy bruising, dark urine, black stools, severe headache, unusual dizziness. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: persistent nausea or vomiting, stomach/abdominal pain, yellowing of eyes/skin. This drug may infrequently cause serious (possibly fatal) complications from the dislodging of solid patches of cholesterol from blood vessel walls which can block the blood supply to parts of your body. If left untreated, this can lead to severe tissue damage (gangrene). Seek immediate medical attention if any of these unlikely but serious side effects occur: painful red rash, dark discoloration of any body part (e.g., purple toe syndrome), sudden intense pain (e.g., back or muscle pain), foot ulcers, unusual change in the amount of urine, vision changes, confusion, slurred speech, one-sided weakness. A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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