vortioxetine (Trintellix - formerly known as Brintellix)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

GENERIC NAME: vortioxetine

BRAND NAME: Trintellix (formerly known as Brintellix)



USES: Vortioxetine is used for the treatment of a certain type of depression known as major depressive disorder (MDD).

SIDE EFFECTS: The most common side effects of vortioxetine treatment are:


As with other antidepressants, vortioxetine may increase the risk of suicidal thoughts or actions in children, teenagers, or young adults within the first few months of treatment.

Other rare but serious side effects are:

  • Serotonin syndrome
  • Abnormal bleeding or bruising
  • Suicidality
  • Seizures
  • Withdrawal symptoms if discontinued too quickly
  • Manic episodes
  • Hives (angioedema
  • Eye problems or vision changes
  • Low levels of salt or sodium (hyponatremia) in blood
Medically Reviewed by a Doctor on 7/1/2016

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