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voriconazole - oral, Vfend (cont.)

DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.This drug should not be used with the following medications because very serious interactions may occur: carbamazepine, certain barbiturates (e.g., phenobarbital, mephobarbital), ergot alkaloids (e.g., ergotamine, dihydroergotamine), rifamycins (e.g., rifampin, rifabutin), ritonavir, sirolimus, St John's wort.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting voriconazole.Many drugs besides voriconazole may affect the heart rhythm (QT prolongation), including amiodarone, dofetilide, pimozide, procainamide, quinidine, sotalol, macrolide antibiotics (such as erythromycin), among others. Therefore, before using voriconazole, report all medications you are currently using to your doctor or pharmacist.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: certain HIV non-nucleoside reverse transcriptase inhibitors (e.g., delavirdine, efavirenz, nevirapine), certain HIV protease inhibitors (e.g., amprenavir, darunavir, nelfinavir, saquinavir), drugs removed from your body by certain liver enzymes (such as cyclosporine, methadone, eplerenone, tacrolimus, birth control pills, "blood thinners" such as warfarin, certain chemotherapy drugs such as sunitinib/dasatinib/lapatinib, vinca alkaloids such as vincristine, "statin" drugs such as lovastatin/simvastatin, benzodiazepines such as triazolam/alprazolam, calcium channel blockers such as felodipine, sulfonylureas such as glipizide/glyburide, proton pump inhibitors such as omeprazole), phenytoin.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.



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