voriconazole - injection, Vfend (cont.)
PRECAUTIONS: Before using voriconazole, tell your doctor or pharmacist if you are allergic to it; or to other azole antifungals (e.g., itraconazole, ketoconazole); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Tell your doctor your medical history, especially of: liver disease, kidney disease, heart problems (e.g., irregular heartbeats, cardiomyopathy), recent chemotherapy, untreated electrolyte imbalance (e.g., low calcium levels).Voriconazole may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can infrequently result in serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that require immediate medical attention. The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may affect the heart rhythm (see also Drug Interactions section). Before using voriconazole, tell your doctor or pharmacist if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using voriconazole safely.This drug may cause vision changes. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely. Do not drive at night.Avoid alcoholic beverages because they can increase the risk of serious liver problems.This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors.Before having surgery, tell your doctor or dentist that you are using this medication.This medication is not recommended for use during pregnancy because it may harm an unborn baby. Therefore, it is important to prevent pregnancy while taking this medication. Consult your doctor for more details and to discuss reliable forms of birth control. It is recommended that men and women using this medication use 2 effective forms of birth control (e.g., condoms and diaphragms with spermicide) while using this medication. If you become pregnant or think you may be pregnant, contact your doctor immediately.It is not known whether this medication passes into breast milk. Breast-feeding is not recommended while using this drug. Consult your doctor before breast-feeding.
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