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February 10, 2012
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voriconazole - injection, Vfend (cont.)

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: certain barbiturates (such as phenobarbital, mephobarbital), certain HIV non-nucleoside reverse transcriptase inhibitors (such as delavirdine, efavirenz, nevirapine), certain HIV protease inhibitors (such as amprenavir, darunavir, nelfinavir, saquinavir, ritonavir), certain medicines to treat seizures (such as carbamazepine, phenytoin), ergot alkaloids (such as ergotamine, dihydroergotamine), rifamycins (such as rifampin, rifabutin), sirolimus, St John's wort, drugs removed from your body by certain liver enzymes (such as cyclosporine, methadone, eplerenone, tacrolimus, birth control pills, certain chemotherapy drugs such as sunitinib/dasatinib/lapatinib,"blood thinners" such as warfarin, "statin" drugs such as lovastatin/simvastatin, benzodiazepines such as triazolam/alprazolam, calcium channel blockers such as felodipine, sulfonylureas such as glipizide/glyburide, vinca alkaloids such as vincristine, proton pump inhibitors such as omeprazole).Many drugs besides voriconazole may affect the heart rhythm (QT prolongation), including amiodarone, dofetilide, pimozide, procainamide, quinidine, sotalol, macrolide antibiotics (such as erythromycin), among others. Therefore, before using voriconazole, report all medications you are currently using to your doctor or pharmacist.



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