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February 10, 2012

vitamin d - oral Glossary of Terms

The following are health and medical definitions of terms that appear in the vitamin d - oral article.

Absorb: 1. To take something in, as through the skin or the intestine.
2. To react with radiation and reduce it in intensity, as with a dose of radiation or transmitted light.
See also: Absorbed dose; Absorption; Malabsorption; Reabsorption.

Absorption: Uptake. In the biomedical sciences, absorption has diverse specific meanings.
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Allergic reaction: The hypersensitive response of the immune system of an allergic individual to a substance.
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Bile: Bile is a yellow-green fluid that is made by the liver, stored in the gallbladder and passes through the common bile duct into the duodenum where it helps digest fat. The principal components of bile are cholesterol, bile salts, and the pigment bilirubin.
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Bile acid: An acid made by the liver that works with bile to break down fats.
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Breast milk: Milk from the breast. Human milk contains a balance of nutrients that closely matches infant requirements for brain development, growth and a healthy immune system. Human milk also contains immunologic agents and other compounds that act against viruses, bacteria, and parasites. Since an infant's immune system is not fully developed until age 2, human milk provides a distinct advantage over formula.
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Breathing: The process of respiration, during which air is inhaled into the lungs through the mouth or nose due to muscle contraction, and then exhaled due to muscle relaxation.

Calcium: A mineral found mainly in the hard part of bones, where it is stored. Calcium is added to bones by cells called osteoblasts and is removed from bones by cells called osteoclasts. Calcium is essential for healthy bones. It is also important for muscle contraction, heart action, nervous system maintenance, and normal blood clotting. Food sources of calcium include dairy foods, some leafy green vegetables such as broccoli and collards, canned salmon, clams, oysters, calcium-fortified foods, and tofu. According to the National Academy of Sciences, adequate intake of calcium is 1,200 milligrams a day (four glasses of milk) for men and women 51 and older, 1,000 milligrams a day for adults 19 through 50, and 1,300 milligrams a day for children 9 through 18. The upper limit for calcium intake is 2.5 grams daily.

Learn more about calcium with evidence-based information on RxList.

Cholesterol: The most common type of steroid in the body, cholesterol has gotten something of a bad name. However, cholesterol is a critically important molecule.
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Cod liver oil: An oil extracted from the liver of the cod. Cod liver oil was once given religiously to children every day as a rich source of vitamins A and D. It was also used to treat children with rickets, a bone disease due to vitamin D deficiency.
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Constipation: Infrequent (and frequently incomplete) bowel movements. The opposite of diarrhea, constipation is commonly caused by irritable bowel syndrome, diverticulosis, and medications (constipation can paradoxically be caused by overuse of laxatives). Colon cancer can narrow the colon and thereby cause constipation. The large bowel (colon) can be visualized by barium enema x-rays, sigmoidoscopy, and colonoscopy. Barring a condition such as cancer, high-fiber diets can frequently relieve the constipation.

Dizziness: Painless head discomfort with many possible causes including disturbances of vision, the brain, balance (vestibular) system of the inner ear, and gastrointestinal system. Dizziness is a medically indistinct term which laypersons use to describe a variety of conditions ranging from lightheadedness, unsteadiness to vertigo.
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Drain: A device for removing fluid from a cavity or wound. A drain is typically a tube or wick. As a verb, to allow fluid to be released from a confined area.

Familial: A condition that is tends to occur more often in family members than expected by chance alone. A familial disease may be genetic (such as cystic fibrosis) or environmental (such as tuberculosis).

FDA: The Food and Drug Administration, an agency within the U.S. Public Health Service, which is a part of the Department of Health and Human Services.
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Flush: (1) A redness of the skin, typically over the cheeks or neck. A flush is usually temporary and brought on by excitement, exercise, fever, or embarrassment. Flushing is an involuntary (uncontrollable) response of the nervous system leading to widening of the capillaries of the involved skin. Also referred to as a blush (or, as a verb, to blush). Flushing may also be caused by medications or other substances that cause widening of the capillaries, such as niacin. (2) Flush also means to wash out a wound or body area.

Generic: 1. The chemical name of a drug. 2. A term referring to the chemical makeup of a drug rather than to the advertised brand name under which the drug may be sold. 3.A term referring to any drug marketed under its chemical name without advertising.

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Herbal: 1. An adjective, referring to herbs, as in an herbal tea.
2. A noun, usually reflecting the botanical or medicinal aspects of herbs; also a book which catalogs and illustrates herbs.
The word "herbal" was pronounced with a silent "h" on both sides of the Atlantic until the 19th century but this usage persists only on the American side.

Hypercalcemia: A higher-than-normal level of calcium in the blood. This can cause a number of nonspecific symptoms, including loss of appetite, nausea, thirst, fatigue, muscle weakness, restlessness, and confusion. Excessive intake of calcium may cause muscle weakness and constipation, affect the conduction of electrical impulses in the heart (heart block) lead to calcium stones (nephrocalcinosis), in the urinary tract, impair kidney function, and interfere with the absorption of iron predisposing to iron deficiency. According to the National Academy of Sciences, adequate intake of calcium is 1 gram daily for both men and women. The upper limit for calcium intake is 2.5 grams daily.

Hypoparathyroidism: Underfunction of the parathyroid glands with deficient production of the hormone parathormone which leads to low blood calcium (hypocalcemia). The parathyroid glands are located adjacent to the thyroid gland. They may be missing due to a birth defect, impaired by autoimmune disease, or surgically removed during thyroid surgery. Treatment is with oral calcium supplements and oral vitamin D. Oral vitamin D increases the gut absorption of calcium in the diet and helps to maintain normal blood calcium levels.

Hypophosphatemia: A less than normal blood level of phosphate. The opposite of hyperphosphatemia.

Itching: An uncomfortable sensation in the skin that feels as if something is crawling on the skin or in the skin, and makes the person want to scratch the affected area.
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Kidney: One of a pair of organs located in the right and left side of the abdomen which clear "poisons" from the blood, regulate acid concentration and maintain water balance in the body by excreting urine. The kidneys are part of the urinary tract. The urine then passes through connecting tubes called "ureters" into the bladder. The bladder stores the urine until it is released during urination.


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Laboratory: A place for doing tests and research procedures and preparing chemicals, etc. Although "laboratory" looks very like the Latin "laboratorium" (a place to labor, a work place), the word "laboratory" came from the Latin "elaborare" (to work out, as a problem, and with great pains), as evidenced by the Old English spelling "elaboratory" designating "a place where learned effort was applied to the solution of scientific problems."

Liver: An organ in the upper abdomen that aids in digestion and removes waste products and worn-out cells from the blood. The liver is the largest solid organ in the body. The liver weighs about three and a half pounds (1.6 kilograms). It measures about 8 inches (20 cm) horizontally (across) and 6.5 inches (17 cm) vertically (down) and is 4.5 inches (12 cm) thick.


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Liver disease: Liver disease refers to any disorder of the liver. The liver is a large organ in the upper right abdomen that aids in digestion and removes waste products from the blood.
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Magnesium: A mineral involved in many processes in the body including nerve signaling, the building of healthy bones, and normal muscle contraction. About 350 enzymes are known to depend on magnesium.
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Malabsorption: The impaired absorption by the intestines of nutrients from food. Malabsorption can be specific and involve sugars, fats, proteins, or vitamins. Alternatively, malabsorption can be general and nonspecific.
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Medical history: 1. In clinical medicine, the patient's past and present which may contain clues bearing on their health past, present, and future. The medical history, being an account of all medical events and problems a person has experienced, including psychiatric illness, is especially helpful when a differential diagnosis is needed.
2. The history of medicine.

Mouth: 1. The upper opening of the digestive tract, beginning with the lips and containing the teeth, gums, and tongue. Foodstuffs are broken down mechanically in the mouth by chewing and saliva is added as a lubricant. Saliva contains amylase, an enzyme that digests starch. 2. Any opening or aperture in the body. The mouth in both senses of the word is also called the os, the Latin word for an opening, or mouth. The o in os is pronounced as in hope. The genitive form of os is oris from which comes the word oral.

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Nutrition: 1) The science or practice of taking in and utilizing foods. 2) A nourishing substance, such as nutritional solutions delivered to hospitalized patients via an IV or IG tube.

Osteomalacia: Softening of bone, particularly in the sense of bone weakened by demineralization (the loss of mineral) and most notably by the depletion of calcium from bone.
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Osteoporosis: Thinning of the bones with reduction in bone mass due to depletion of calcium and bone protein. Osteoporosis predisposes a person to fractures, which are often slow to heal and heal poorly. It is more common in older adults, particularly post-menopausal women; in patients on steroids; and in those who take steroidal drugs. Unchecked osteoporosis can lead to changes in posture, physical abnormality (particularly the form of hunched back known colloquially as "dowager's hump"), and decreased mobility.
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Pharmacist: A professional who fills prescriptions, and in the case of a compounding pharmacist, makes them. Pharmacists are familiar with medication ingredients, interactions, cautions, and hints.
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Phosphate: A form of phosphoric acid. Calcium phosphate makes bones and teeth hard.

Phosphorus: An essential element in the diet and a major component of bone. Phosphorus is also found in the blood, muscles, nerves, and teeth. It is a component of adenosine triphosphate (ATP), the primary energy source in the body.

Poison: Any substance that can cause severe distress or death if ingested, breathed in, or absorbed through the skin. Many substances that normally cause no problems, including water and most vitamins, can be poisonous if taken in too large of a quantity. Poison treatment depends on the substance: if there are treatment instructions on the substance's container and you are sure it contained no other item, follow those directions immediately. Always contact your nearest Poison Control Center if you are concerned about possible poison ingestion.

Poison Control Center: Special information centers set up to inform Americans about how to respond to potential poisoning. These centers maintain a database of poisons and appropriate emergency treatment. The Poison Control Center in your area should be listed with other community service numbers in the front of your telephone book, and can also be reached immediately through any telephone operator.
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Pregnancy: The state of carrying a developing embryo or fetus within the female body. This condition can be indicated by positive results on an over-the-counter urine test, and confirmed through a blood test, ultrasound, detection of fetal heartbeat, or an X-ray. Pregnancy lasts for about nine months, measured from the date of the woman's last menstrual period (LMP). It is conventionally divided into three trimesters, each roughly three months long.
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Prescription: A physician's order for the preparation and administration of a drug or device for a patient. A prescription has several parts. They include the superscription or heading with the symbol "R" or "Rx", which stands for the word recipe (meaning, in Latin, to take); the inscription, which contains the names and quantities of the ingredients; the subscription or directions for compounding the drug; and the signature which is often preceded by the sign "s" standing for signa (Latin for mark), giving the directions to be marked on the container.

Rash: Breaking out (eruption) of the skin. Medically, a rash is referred to as an exanthem.

Recommended Dietary Allowance: The RDA, the estimated amount of a nutrient (or calories) per day considered necessary for the maintenance of good health by the Food and Nutrition Board of the National Research Council/ National Academy of Sciences. The RDA is updated periodically to reflect new knowledge. It is popularly called the Recommended Daily Allowance.

Rickets: A disease of infants and children that disturbs normal bone formation (ossification). Rickets is a failure to mineralize bone. This softens bone (producing osteomalacia) and permits marked bending and distortion of bones. Up through the first third of the 20th century, rickets was largely due to lack of direct exposure to sunlight or lack of vitamin D. Sunlight provides the necessary ultraviolet rays. These rays do not pass through ordinary window glass. Once the role of vitamin D in rickets was discovered, cod liver oil (which is rich in vitamin D) became a favored, if not too tasty, remedy. Thanks to such supplements of vitamin D, nutritional rickets has become relatively rare in industrialized nations. It still occurs, for example, in breast-fed babies whose mothers are underexposed to sunlight and in dark-skinned babies who are not given vitamin D supplements. And in unindustrialized countries, vitamin D deficiency rickets continues to be a problem. Rickets in North America and Europe now is usually not nutritional.
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Sunscreen: A substance that blocks the effect of the sun's harmful rays. Using lotions that contain sunscreens can reduce the risk of skin cancer, including melanoma.

Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
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Syndrome: A set of signs and symptoms that tend to occur together and which reflect the presence of a particular disease or an increased chance of developing a particular disease.
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Tiredness: See: Tired.

Vitamin D: A steroid vitamin which promotes the intestinal absorption and metabolism of calcium and phosphorus. Under normal conditions of sunlight exposure, no dietary supplementation is necessary because sunlight promotes adequate vitamin D synthesis in the skin. Deficiency can lead to bone deformity (rickets) in children and bone weakness (osteomalacia) in adults.
See the entire definition of Vitamin D

Vitamins: The word "vitamin" was coined in 1911 by the Warsaw-born biochemist Casimir Funk (1884-1967). At the Lister Institute in London, Funk isolated a substance that prevented nerve inflammation (neuritis) in chickens raised on a diet deficient in that substance. He named the substance "vitamine" because he believed it was necessary to life and it was a chemical amine. The "e" at the end was later removed when it was recognized that vitamins need not be amines.
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What is rickets?

Rickets is a disorder caused by a deficiency of vitamin D, calcium, or phosphate. It leads to softening and weakening of the bones and is seen most commonly in children 6-24 months of age. There are several subtypes of rickets, including hypophosphatemic rickets (vitamin-D-resistant rickets), kidney rickets (renal osteodystrophy), and, most commonly, nutritional rickets (caused by dietary deficiency of vitamin D, calcium, or phosphate). Classic nutritional rickets is also medically termed osteomalacia.

What is the history of rickets?

Roman descriptions of individuals with rickets can be found as early as the second century, and in the 1640s, the condition was well documented as a common bone ailment across England. Unfortunately, the scientifically proven cause of rickets was not identified until the 1920s, and by the 1930s, public-health initiatives included recommending fortification of milk with vi...

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