verapamil, Calan, Verelan, Verelan PM, Isoptin, Isoptin SR, Covera-HS (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
GENERIC AVAILABLE: Yes
PREPARATIONS: Immediate release tablets: 40, 80, and 120 mg; sustained release caplets: 120, 180, 240,and 360 mg; extended release tablets: 100, 120, 180, 200, 240, and 300 mg; Injection: 2.5 mg/mL
STORAGE: Verapamil should be stored at room temperature 15-30 C (59-86 F) in a tight, light- resistant container.
PRESCRIBED FOR: Chest pain (angina) occurs because insufficient oxygen-carrying blood is delivered to the muscles of the heart. Insufficient oxygen-carrying blood may be the result of blockage of blood flow in the coronary arteries due to coronary artery disease or spasm, or an increase in physical exertion that increases the workload of the heart and the demand by the heart for oxygen. Verapamil is used for the treatment and prevention of angina resulting from coronary artery disease and spasm as well as from exertion. Verapamil also is used in the treatment of high blood pressure. Verapamil slows electrical conduction of the electrical impulses through the heart and has been used to in treat abnormally fast heart rhythms such as atrial fibrillation, and in the prevention of recurrent episodes of rapid heart rhythm originating from the atria. Although it is not approved by the FDA for migraines, verapamil is used for preventing migraine.
DOSING: Verapamil can be taken with food.
DRUG INTERACTIONS: Concurrent use of verapamil with a beta blocker (another class of medications that slow heart rate) can cause profound and dangerous reductions in heart rate. Verapamil can raise the levels of some drugs in blood including digoxin (Lanoxin), theophylline (Slo-Bid), cyclosporin, and carbamazepine (Tegretol). Therefore, monitoring of the levels of these drugs is important to avoid toxicity.
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