verapamil, Calan, Verelan, Verelan PM, Isoptin, Isoptin SR, Covera-HS (cont.)

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PREPARATIONS: Immediate release tablets: 40, 80, and 120 mg; sustained release caplets: 120, 180, 240,and 360 mg; extended release tablets: 100, 120, 180, 200, 240, and 300 mg; Injection: 2.5 mg/mL

STORAGE: Verapamil should be stored at room temperature 15-30 C (59-86 F) in a tight, light- resistant container.

PRESCRIBED FOR: Chest pain (angina) occurs because insufficient oxygen-carrying blood is delivered to the muscles of the heart. Insufficient oxygen-carrying blood may be the result of blockage of blood flow in the coronary arteries due to coronary artery disease or spasm, or an increase in physical exertion that increases the workload of the heart and the demand by the heart for oxygen. Verapamil is used for the treatment and prevention of angina resulting from coronary artery disease and spasm as well as from exertion. Verapamil also is used in the treatment of high blood pressure. Verapamil slows electrical conduction of the electrical impulses through the heart and has been used to in treat abnormally fast heart rhythms such as atrial fibrillation, and in the prevention of recurrent episodes of rapid heart rhythm originating from the atria. Although it is not approved by the FDA for migraines, verapamil is used for preventing migraine.

DOSING: Verapamil can be taken with food.

  • Angina (immediate release formulations): 80-160 mg three times daily. Angina (extended release formulations): 180-540 mg at bedtime.
  • Hypertension (immediate release): 80-320 mg twice daily. Hypertension (extended release): 120-480 mg once or twice daily depending on the brand.
  • Migraine: 160-320 mg three to four times daily.

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