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VERAPAMIL-INJECTION, Isoptin (cont.)

SIDE EFFECTS: Nausea and headache are unlikely but could occur. If these persist or worsen, notify your doctor. Unlikely but report promptly: irregular or very slow heartbeat, fainting or dizziness, difficulty breathing, leg or ankle swelling, rapid weight gain, seizures. Very unlikely but report immediately: fever, malaise, stomach/abdominal pain, yellowing eyes or skin, dark urine, excessive sweating. In the unlikely event of an allergic reaction, notify your doctor immediately. Symptoms of an allergic reaction include: skin rash, hives, itching, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor your medical history, especially of: allergies (especially drug allergies), heart problems, liver problems, kidney disease, very low blood pressure, muscular dystrophy, brain tumors (cancer). Verapamil prolongs and intensifies the effects of alcohol in your system. Avoid (or very carefully limit) alcoholic beverages while using this medication. Caution is advised when this drug is used in the elderly. Caution is advised when this drug is used in neonates and infants. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This drug is excreted into breast milk and a decision should be made whether to stop the drug or avoid breast-feeding. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of all nonprescription or prescription medication you may use, especially of: beta-blockers (e.g., propranolol, timolol- including eye drops), intravenous (IV) calcium, digoxin, high blood pressure drugs (e.g., water pills, ACE inhibitors), quinidine, disopyramide, carbamazepine, lithium, flecainide, theophylline, cyclosporine, neuromuscular blocking drugs (e.g., for surgery), inhaled anesthetics that can decrease the heart's pumping action. Mixing of IV verapamil and IV sodium bicarbonate/saline solutions, nafcillin, albumin, amphotericin B, hydralazine, aminophylline or trimethoprim/sulfa is not recommended (incompatible chemicals). Do not start or stop any medicine without doctor or pharmacist approval.



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