valsartan/hydrochlorothiazide (Diovan HCT) (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
Patients allergic to sulfa may also be allergic to hydrochlorothiazide because of the similarity in the chemical structure of the two medications.
Hydrochlorothiazide can worsen kidney failure and is used with caution in patients with kidney disease.
Hydrochlorothiazide can lower blood potassium, sodium, and magnesium levels. Low potassium and magnesium levels can lead to abnormalities in heart rhythm, especially in patients already taking digoxin (Lanoxin). During hydrochlorothiazide treatment, supplementation with potassium is common to prevent low potassium levels.
Blood uric acid levels can increase during hydrochlorothiazide treatment, and this elevation may cause an episode of acute gout in some individuals.
GENERIC AVAILABLE: Yes
PREPARATIONS: Tablets: 80/12.5, 160/12.5, 160/25, 320/12.5, and 320 mg/25 mg
STORAGE: Valsartan/hydrochlorothiazide tablets should be stored between 15 C and 30 C (59 and 86 F).
DOSING: The recommended starting dose of valsartan/hydrochlorothiazide is 80/12.5 to 160 mg/ 12.5 mg by mouth once daily. If blood pressure is not controlled, doses may be increased every 1 to 2 weeks to a maximum of 320 mg/25 mg per day.
Medically Reviewed by a Doctor on 12/23/2014
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