valsartan/hydrochlorothiazide (Diovan HCT) (cont.)

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Medical and Pharmacy Editor:

Hydrochlorothiazide is a diuretic (water pill) used for treating high blood pressure and accumulation of fluid. It works by blocking salt and water reabsorption in the kidneys, thus causing increased output of urine containing increased amounts of water and salt (diuresis). The mechanism of its action in lowering high blood pressure is not well understood. The combination of valsartan and hydrochlorothiazide reduces blood pressure more that either drug alone.

The FDA approved valsartan/hydrochlorothiazide in March 1998.

PRESCRIBED FOR: Valsartan/hydrochlorothiazide is used for the treatment of blood pressure in patients with or without a history of congestive heart failure.

SIDE EFFECTS: Side effect of valsartan/hydrochlorothiazide are the same as its individual components.

Valsartan is generally well-tolerated. The most common side effects of valsartan include:

Patients also may experience:

Rare but serious side effects of valsartan are:

  • rhabdomyolysis (inflammation and destruction of muscle), and
  • angioedema (swelling of soft tissues including those of the throat and larynx).

Side effects of hydrochlorothiazide include:

Medically Reviewed by a Doctor on 12/23/2014


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