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February 10, 2012
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valproate sodium-injection, Depacon (cont.)

SIDE EFFECTS: Nausea, drowsiness, dizziness, headache, diarrhea, or pain/redness/swelling at the injection site, altered taste, sweating, or nervousness may occur. If any of these effects persist or worsen, notify your doctor promptly. Tell your doctor immediately if any of these serious side effects occur: vomiting, tingling or numbness of the hands/feet, vision changes, stomach/abdominal pain, flu-like symptoms (e.g., fever, chills, sore throat, muscle aches, unusual tiredness/weakness), tremor, loss of coordination, forgetfulness, rash, unusual hair loss, loss of appetite. Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes (e.g., hallucinations, depression), trouble breathing, swelling/weight gain, ringing in the ears. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: severe stomach pain, chest pain, yellowing eyes or skin, dark urine, swelling of the face, unusual bleeding or bruising. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor your medical history, especially of: liver problems, pancreas problems (pancreatitis), blood problems (e.g., thrombocytopenia), metabolism problems (e.g., hyperammonemia, thyroid disorders, urea cycle disorder), seizure history/description, mental retardation, depression, brain disease, recent head trauma, upcoming surgery. This drug may make you dizzy or drowsy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. This medication should be used with caution in children, especially less than 2 years of age, because they may be more likely to have serious side effects (e.g., liver damage) from this medication. Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug. This medication is not recommended for use during pregnancy. Consult your doctor for more details. This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.



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